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M.S. Molecular Biology, University of Milan Ph.D. Genetics and Molecular Biology, University of Milan

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Chiolo, I., Minoda, A., Colmenares, S. U., Polyzos, A., Costes, S. V., Karpen, G. H. (2011). Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair. Cell. Vol. 144 (5), pp. 732-44. Chiolo*, I., Robert*, T., Vanoli*, F., Shubassi, G., Bernstein, K. A., Rothstein, R., Botrugno, O. A., Parazzoli, D., Oldani, A., Minucci, S., Foiani, M. (2011). HDACs link the DNA damage response, processing of double-strand breaks and autophagy. Nature. Vol. 471 (7336), pp. 74-9. *Co-first authors. Costes, S. V., Chiolo, I., Pluth, J. M., Barcellos-Hoff, M. H., Jakob, B. (2010). Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization. Mutation Research. Vol. 704 (1-3), pp. 78-87. Tavecchio, M., Simone, M., Erba, E., Chiolo, I., Liberi, G., Foiani, M., D'Incalci, M., Damia, G. (2008). Role of homologous recombination in trabectedin-induced DNA damage. Eur J Cancer. Vol. 44 (4), pp. 609-18. Chiolo, I., Saponaro, M., Baryshnikova, A., Kim, J., Seo, Y., Liberi, G. (2007). The human F-Box DNA helicase FBH1 faces Saccharomyces cerevisiae Srs2 and postreplication repair pathway roles. Mol Cell Biol. Vol. 27 (21), pp. 7439-50. Chiolo, I., Carotenuto, W., Maffioletti, G., Petrini, J. H., Foiani, M., Liberi, G. (2005). Srs2 and Sgs1 DNA helicases associate with Mre11 in different subcomplexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation. Mol Cell Biol. Vol. 25 (13), pp. 5738-51. Liberi, G., Maffioletti, G., Lucca, C., Chiolo, I., Baryshnikova, A., Cotta-Ramusino, C., Lopes, M., Pellicioli, A., Haber, J. E., Foiani, M. (2005). Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase. Genes Dev. Vol. 19 (3), pp. 339-50. Liberi, G., Chiolo, I., Pellicioli, A., Lopes, M., Plevani, P., Muzi-Falconi, M., Foiani, M. (2000). Srs2 DNA helicase is involved in checkpoint response and its regulation requires a functional Mec1-dependent pathway and Cdk1 activity. EMBO J. Vol. 19 (18), pp. 5027-38.

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