Zhao, Weian - University of California, Irvine - Department of Biological Chemistry

个人简介

Academic Distinctions Editorial Board Member of Journal Stem Cell International Editorial Board Member of Journal Nanotechnology Selected participant of the 60th Meeting of Nobel Laureates, Lindau, Germany Executive board member of the 35th Northeast Bioengineering Conference, Boston, Materials Research Society (MRS) Graduate Student Silver Award Chinese Government Award for Outstanding Self-Financed Student Abroad Student competition award in 89th Canadian Chemistry Conference and Exhibition Future Star scholarship, Shandong University Appointments Human Frontier Science Program Postdoctoral Fellow Harvard Medical School Brigham and Women's Hospital Harvard-MIT Division of Health Science & Technology Harvard Stem Cell Institute

研究领域

My research aims to understand and ultimately control the fate of the transplanted stem cells in the body (i.e. where they go and what they do), which will lead to effective and safe clinical medicine. We study the biological, therapeutic and detrimental functions of transplanted stem cells in vivo, which will eventually allow us to better utilize them to treat a variety of diseases including cancer and stroke. Furthermore, we are developing bioengineered tools including microfluidics, nanoparticles and aptamers to tackle unmet challenges in disease diagnosis and global health.

近期论文

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Debanjan Sarkar, Sebastian Schaefer, Joel A. Spencer, Weian Zhao, Dawn P. Spelke, Rohit Karnit, Charles P. Lin, Jeffrey M. Karp.* Engineered cell homing. 2011, Blood. In press Weian Zhao,* Jeffrey M. Karp*. Bioengineering nanotechnology: towards the clinic. Nanotechnology, 2011, In press (Editorial) Chenjie Xu, Luye Mu, Isaac Roes, David Miranda-Nieves, Weian Zhao, Jeffrey M. Karp. Tracking of Transplanted Cells in Cell Therapy with Nanoparticle-based Imaging Probes. Nanotechnology, 2011, In press (Special Issue of Bioengineered Nanotechnology). Weian Zhao, Sebastian Schafer, Jonghoon Choi, Yvonne J. Yamanaka, Maria L. Lombardi, Suman Bose, Alicia L. Carlson, Joseph A. Phillips, Weisuong Teo, Ilia A. Droujinine, Cheryl Cui, Rakesh K. Jain, Jan Lammerding, J. Christopher Love, Charles P. Lin, Debanjan Sarkar, Rohit Karnik, and Jeffrey M. Karp.* Cell surface sensors for real-time probing of cellular environments. Nature Nanotechnology, 2011, 6, 524-531. Highlighted in Nature Biotechnology. Weian Zhao, Weili Loh, Ilia A. Droujinine, Weisuong Teo, Namit Kumar, Sebastian Schafer, Cheryl Cui, Liang Zhang, Debanjan Sarkar, Rohit Karnik and Jeffrey M. Karp.* Mimicking the inflammatory cell adhesion cascade by nucleic acid aptamer programmed cell-cell interactions. The FASEB Journal, 2011, 25, 3045-3056. Weian Zhao, Grace Teo, Namit Kumar, Jeffrey M. Karp,* Chemistry and material science at the cell surface. Materials Today, 2010, 13, 14-21. Invited review. Debanjan Sarkar, Praveen Kumar Vemula, Weian Zhao, Ashish Gupta, Jeffrey M. Karp.* Surface Modification of mesenchymal stem cells with self-assembled vesicles for systemic cell targeting. Biomaterials, 2010, 31, 5266-5274. C. Keith Ozaki,* Dimitrios Mitsouras, Praveen K. Vemula, Dia Smiley, Ming Tao, Peng Yu, Christina Campagna, Weian Zhao, Robert V. Mulkern, Jeffrey M. Karp, Frank Rybicki. Novel Implantable vein graft contrast yields enhanced outer wall definition in magnetic resonance imaging. Journal of Vascular Surgery, 2010, 51, 533. Weian Zhao, Jeffrey M. Karp.* Control cell fate in vivo. ChemBioChem, 2009, 10, 2308-2310. Highlight article. Weian Zhao, Jeffrey M. Karp.* Tumour targeting: Nanoantennas heat up. Nature Materials 2009, 8, 453-454. News and Views article in Special issue on biomaterials. Weian Zhao, Elodie Pacard, Carole Chaix-Bauvais, Christian Pichot, Michael A. Brook*. Covalent assembly of silica nanoparticle aggregates for oligonucleotide synthesis. Colloids and Surface A, 2009, 339, 26-34. Weian Zhao,* Albert van der Berg.* Lab on Paper, Lab Chip. 2008, 8, 1988-91. Commentary article in Special Issue on point-of-care diagnostics. Weian Zhao, Monsur M. Ali, Sergio D. Aguirre, Michael A. Brook* and Yingfu Li*. Paper-based bioassays using gold nanoparticle colorimetric probes. Anal. Chem. 2008, 80, 8431-7. Weian Zhao, Michael A. Brook,* Yingfu Li*. Design of gold nanoparticle based colorimetric biosensing assays. ChembioChem 2008, 9, 2363-71. Review article. Most accessed articles in 2008-2009; Most cited in 2010. Weian Zhao, Monsur M. Ali, Michael A. Brook* and Yingfu Li*. Rolling circle amplification: new applications in nanotechnology and functional nucleic acid-based biodection. Angew. Chem. Int. Ed. 2008, 47, 6330-6337. Review article.