Hui, Elliot - University of California, Irvine - Department of Biomedical Engineering

个人简介

Education B.S., MIT, Physics B.S., MIT, Electrical Engineering and Computer Science Ph.D., UC Berkeley, Electrical Engineering

研究领域

The Hui Lab is focused on leveraging microtechnology to understand and improve human health. Spatial Cell Biology - How does the spatial organization of cells within tissue determine the emergent biological function? Our platforms allow dynamic manipulation of tissue organization during cell culture, enabling unconventional experiments and new insights into cell-cell interaction. We are engaged in problems such as tumor angiogenesis during cancer progression, and the determination of cellular fate in stem cell development. Global Health Diagnostics - How can we bring hospital laboratory tests into the homes of families living in limited-resource settings? We are building computers that run on air pressure instead of electricity. We envision automated laboratories on a microchip that can be cheaply stamped out of plastic

近期论文

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Jones KA, Li DJ, Hui EE, Sellmyer MA, Prescher JA (2015). Visualizing Cell Proximity with Genetically Encoded Bioluminescent Reporters. ACS Chemical Biology, in press. Duncan PN, Ahrar S, Hui EE (2015). Scaling of Pneumatic Digital Logic Circuits. Lab on a Chip, 15:1360-1365. Huntsman MAH, Olivares FJ, Tran CP, Billimek J, Hui EE (2014). Pain Reduction and Financial Incentives to Improve Glucose Monitoring Adherence in a Community Health Center. PLoS ONE 9(12):e114875. doi: 10.1371/journal.pone.0114875 Spencer KH, Kim MY, Hughes CCW, Hui EE (2014). A Screen for Short-Range Paracrine Interactions. Integrative Biology, 6(4):382-7. [Cover Article] Kim MY, Li DJ, Pham LK, Wong BG, Hui EE (2014). Microfabrication of High-Resolution Porous Membranes for Cell Culture. Journal of Membrane Science, 452(2):460-9. Ahrar S, Hwang M, Duncan PN, Hui EE (2014). Microfluidic Serial Dilution Ladder. Analyst, 139(1):187-90 Duncan PN, Nguyen TV, Hui EE (2013). Pneumatic Oscillator Circuits for Timing and Control of Integrated Microfluidics. Proceedings of the National Academy of Sciences 110(45):18104-09. [Featured in PNAS First Look.] Rao N, Grover GN, Vincent LG, Evans SC, Choi YS, Spencer KH, Hui EE, Engler AJ, Christman KL (2013). A co-culture device with a tunable stiffness to understand combinatorial cell-cell and cell-matrix interactions. Integrative Biology 5(11):1344-54. [Cover Article] Hui EE, Li C, Agrawal A, Bhatia SN (2013). Macro-to-micro interface for the control of cellular organization. Journal of Microelectromechanical Systems. 10.1109/JMEMS.2013.2278813, In press. Wong BG, Paz A, Corrado MA, Ramos BR, Cinquin A, Cinquin O, Hui EE (2013). Live imaging reveals active infiltration of mitotic zone by its stem cell niche. Integrative Biology 5(7):976-82. Ahrar S, Nguyen TV, Shi Y, Ikrar T, Xu X, Hui EE (2013). Optical stimulation and imaging of functional brain circuitry in a segmented laminar flow chamber. Lab Chip 13(4):536-41. Rao N, Evans S, Stewart D, Spencer KH, Sheikh F, Hui EE, Christman KL (2013). Fibroblasts influence muscle progenitor differentiation and alignment in contact independent and dependent manners in organized co-culture devices. Biomedical Microdevices 15(1):161-9.