Cumsky, Michael G. - University of California, Irvine - Department of Molecular Biology and Biochemistry

研究领域

Mitochondrial protein import; regulation of gene expression in yeast

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Pam16 has an essential role in the mitochondrial protein import motor. Frazier AE, Dudek J, Guiard B, Voos W, Li Y, Lind M, Meisinger C, Geissler A, Sickmann A, Meyer HE, Bilanchone V, Cumsky MG, Truscott KN, Pfanner N, Rehling P. Nat Struct Mol Biol. 2004 Mar;11(3):226-33. Epub 2004 Feb 15. Gartner, F., W. Voos, A. Querol, B.R. Miller, E. Craig, M.G. Cumsky, and N. Pfanner. 1995. Mitochondrial import of cytochrome c oxidase subunit Va characterized with yeast mutants: independence from surface receptors but requirement for the translocase function of mitochondrial hsp70. J. Biol. Chem. 270:3788-3795. Lambert, J.R., V. W. Bilanchone, and M.G. Cumsky. 1994. The ORD1 gene encodes a transcription factor involved in oxygen regulation and is identical to IXR1, a gene that confers cisplatin sensitivity to Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 91:7345-7349.