Wong, David - University of California, Los Angeles

个人简介

David T.W. Wong, D.M.D., D.M.Sc. is the Felix and Mildred Yip Endowed Chair in Dentistry and a Professor in the Section of Oral Biology in the Division of Oral Biology and Medicine. He is the Associate Dean of Research and the Director of the UCLA Center for Oral/Head and Neck Research. He is an active scientist in oral cancer and saliva diagnostics research. He has authored over 230 peer reviewed scientific publications. He is a fellow of the American Association for the Advancement of Sciences (AAAS), past member of the ADA Council of Scientific Affairs and the past president of American Association of Dental Research (AADR).

研究领域

My laboratory currently has three research directions in head and neck cancer research: Discoveries, Pathogenesis and a Translational portfolio of oral fluid-based molecular diagnostics.

近期论文

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Deshpande, A M, Khalid, O, Kim, J J, Kim, Y, Lindgren, A, Clark, A T, and Wong, D T Cdk2ap2 is a novel regulator for self-renewal of murine embryonic stem cells. Stem Cells Dev, 2012; 21: 3010-3018. PMCID: 3475145. Kim, J J, Khalid, O, Vo, S, Sun, H H, Wong, D T, and Kim, Y A novel regulatory factor recruits the nucleosome remodeling complex to wingless integrated (wnt) signaling gene promoters in mouse embryonic stem cells. J Biol Chem, 2012; 287: 41103-41117. PMCID: 3510811. Spielmann, N, Ilsley, D, Gu, J, Lea, K, Brockman, J, Heater, S, Setterquist, R, and Wong, D T The human salivary RNA transcriptome revealed by massively parallel sequencing. Clin Chem, 2012; 58: 1314-1321. Zhang, L, Farrell, J J, Zhou, H, Elashoff, D, Akin, D, Park, N H, Chia, D, and Wong, D T Salivary Transcriptomic Biomarkers for Detection of Resectable Pancreatic Cancer. Gastroenterology, 2010; 138: 949-957 e947. PMCID: PMC2831159. Matse, J H, Yoshizawa, J, Wang, X, Elashoff, D, Bolsher, J G, Veerman, E C, Bloemena, E, and Wong, D T Discovery and pre-validation of salivary extracellular microRNA biomarkers panel for the non-invasive detection of benign and malignant parotid gland tumors. Clin Cancer Res, 2013, in press.