Wu, Benjamin M - University of California, Los Angeles

个人简介

Education DDS, University of Pacific, 1987 Residency in Prosthodontics, Harvard University, 1995 PhD, Materials Engineering, Massachusetts Institute of Technology, 1998 Awards and Recognitions Active Fellow, Academy of Prosthodontics, 2007 – present Northrop Grumman Teaching Award, UCLA School of Engineering, 2004 Faculty Service Award, UCLA Biomedical Engineering Student Society, 2003 Research Enhancement Initiative Award, UCLA Academic Senate, 2001 Dentist Scientist Award, NIH, 1992-1997 Faculty Member, California NanoSystems Institute Faculty Member, UCLA Cardiovascular Stem Cell Research Center Faculty Member, UCLA Brain Research Institute Co-Director, Weintraub Center for Reconstructive Biotechnology

研究领域

Benjamin Wu, D.D.S., Ph.D., is a practicing clinician and biomaterial scientist. His research brings to bear bioengineering approaches to regenerate lost tissues based on the following biomimetic strategy: (i) learn from natural developmental biology, wound healing, and tissue remodeling; (ii) copy nature and engineer biomimetic microenvironments to promote tissue repair; and (iii) investigate the mechanisms by which progenitor cells and biomolecules interact with engineered microenvironments, which can be formed with a combination of surface bound and/or diffusible biochemical signals and/or biomechanical signals. The projects summarized below demonstrate the application of this general strategy to solve significant clinical problems.

近期论文

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Transplantation of Enteric Cells Expressing p75 in the Rodent Stomach. Geisbauer CL, Chapin JC, Wu BM, Dunn JC. J Surg Res. 2012 May; 174(2):257-65. Epub 2011 Jan 8. Stability comparison between commercially available mini-implants and a novel design. Hong C, Lee H, Webster R, Kwak J, Wu BM, Moon W. Angle Orthod. 2011 Jul; 81(4):692-9. Epub 2011 Feb 9. Nell-1 enhances bone regeneration in a rat critical-sized femoral segmental defect model. Li W, Zara JN, Siu RK, Lee M, Aghaloo T, Zhang X, Wu BM, Gertzman AA, Ting K, Soo C. Plast Reconstr Surg. 2011 Feb;127(2):580-7. High Doses of Bone Morphogenetic Protein 2 Induce Structurally Abnormal Bone and Inflammation In Vivo. Zara JN, Siu RK, Zhang X, Shen J, Ngo R, Lee M, Li W, Chiang M, Chung J, Kwak J, Wu BM, Ting K, Soo C. Tissue Eng Part A. 2011 May; 17(9-10):1389-99. Epub 2011 Mar 3. Osteoblast interactions within a biomimetic apatite microenvironment. Tsang EJ, Arakawa CK, Zuk PA, Wu BM. Ann Biomed Eng. 2011 Apr;39(4):1186-200. Epub 2011 Jan 14. The enhancement of VEGF-mediated angiogenesis by polycaprolactone scaffolds with surface cross-linked heparin. Singh S, Wu BM, Dunn JC. Biomaterials. 2011 Mar;32(8):2059-69. Epub 2010 Dec 13. Nell-1 protein promotes bone formation in a sheep spinal fusion model. Siu RK, Lu SS, Li W, Whang J, McNeill G, Zhang X, Wu BM, Turner AS, Seim HB, Hoang P, Wang JC, Gertzman AA, Ting K, Soo C. Tissue Eng Part A. 2011 Apr;17(7-8):1123-35. Epub 2011 Feb 8. Enhancing the lateral-flow immunoassay for viral detection using an aqueous two-phase micellar system. Mashayekhi F, Chiu RY, Le AM, Chao FC, Wu BM, Kamei DT. Anal Bioanal Chem. 2010 Dec;398(7-8):2955-61. Epub 2010 Sep 24. Incorporation of multicellular spheroids into 3-D polymeric scaffolds provides an improved tumor model for screening anticancer drugs. Ho WJ, Pham EA, Kim JW, Ng CW, Kim JH, Kamei DT, Wu BM. Cancer Sci. 2010 Dec;101(12):2637-43. Adipose-derived stem cells and BMP2: part 2. BMP2 may not influence the osteogenic fate of human adipose-derived stem cells. Zuk P, Chou YF, Mussano F, Benhaim P, Wu BM. Connect Tissue Res. 2011 Apr;52(2):119-32. Epub 2010 Aug 11.