个人简介
1985年获复旦大学生物系学士,1990、1993年分获美国耶鲁大学病毒学硕士、博士。1993-1997美国美国耶鲁大学从事病毒学博士后工作,1998年起美国加州大学洛杉矶分校(UCLA)分别担任助理教授、副教授、教授。现为美国加州大学洛杉矶分校(UCLA)教授、博士生导师。美国加州大学洛杉矶分校医学院(UCLA David Geffen School of Medicine)副院长。肿瘤相关病毒以及病毒基因研究领域国际知名专家;美国微生物学会、病毒学会、肿瘤学会成员,并担任多家国际期刊编委;承担多项美国NIH研究项目; 浙江大学医学院顾问;浙江大学永谦讲座教授,博士生导师。
研究领域
肿瘤相关病毒复制机理/肿瘤相关病毒疫苗研究/病毒系统生物学
近期论文
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Qi Hangfei, Chu Virginia, Wu Nicholas C, Chen Zugen, Truong Shawna, Brar Gurpreet, Su Sheng-Yao, Du Yushen, Arumugaswami Vaithilingaraja, Olson C Anders, Chen Shu-Hua, Lin Chung-Yen, Wu Ting-Ting, Sun Ren Systematic identification of anti-interferon function on hepatitis C virus genome reveals p7 as an immune evasion proteinProceedings of the National Academy of Sciences of the United States of America, 2017; 114(8): 2018-2023.
Dai Xinghong, Li Zhihai, Lai Mason, Shu Sara, Du Yushen, Zhou Z Hong, Sun Ren In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus Nature, 2017; 541(7635): 112-116.
Gong Danyang, Kim Yong Hoon, Xiao Yuchen, Du Yushen, Xie Yafang, Lee Kevin K, Feng Jun, Farhat Nisar, Zhao Dawei, Shu Sara, Dai Xinghong, Chanda Sumit K, Rana Tariq M, Krogan Nevan J, Sun Ren, Wu Ting-Ting A Herpesvirus Protein Selectively Inhibits Cellular mRNA Nuclear Export Cell host & microbe, 2016; 20(5): 642-653.
Du Yushen, Wu Nicholas C, Jiang Lin, Zhang Tianhao, Gong Danyang, Shu Sara, Wu Ting-Ting, Sun Ren Annotating Protein Functional Residues by Coupling High-Throughput Fitness Profile and Homologous-Structure Analysis mBio, 2016; 7(6): 642-653.
Wu Nicholas C, Dai Lei, Olson C Anders, Lloyd-Smith James O, Sun Ren Adaptation in protein fitness landscapes is facilitated by indirect paths eLife, 2016; 5(17): 19895-904.
Zhang Tian-Hao, Wu Nicholas C, Sun Ren A benchmark study on error-correction by read-pairing and tag-clustering in amplicon-based deep sequencing BMC genomics, 2016; 17(17): 108.
Wu Nicholas C, Olson C Anders, Sun Ren High-throughput identification of protein mutant stability computed from a double mutant fitness landscape Protein science : a publication of the Protein Society, 2016; 25(2): 530-9.
Wu Nicholas C, Du Yushen, Le Shuai, Young Arthur P, Zhang Tian-Hao, Wang Yuanyuan, Zhou Jian, Yoshizawa Janice M, Dong Ling, Li Xinmin, Wu Ting-Ting, Sun Ren Coupling high-throughput genetics with phylogenetic information reveals an epistatic interaction on the influenza A virus M segment BMC genomics, 2016; 17(2): 46.
Feng Jiaying, Gong Danyang, Fu Xudong, Wu Ting-ting, Wang Jane, Chang Jennifer, Zhou Jingting, Lu Gang, Wang Yibin, Sun Ren M1 of Murine Gamma-Herpesvirus 68 Induces Endoplasmic Reticulum Chaperone Production Scientific reports, 2015; 5(7): 17228.