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个人简介

Education BS, University of California, San Diego, 1997 PhD, John Hopkins University, 2004 Post-doctoral fellow, Stanford University, 2004-2006 Research Fellow, Stanford University, 2006-2008 Positions Visiting Scientist, University of Auckland, Bioengineering Institute, Auckland MRI Research Group, 2008 (Winter)

研究领域

Professor Ennis is interested in both the basic science and clinical applications of MRI for evaluating cardiovascular structure, function, and remodeling. Work in his laboratory uses a principled combination of theory, simulation, and experimental work to bring improvements to the imaging speed and accuracy of cardiovascular MRI exams. In particular, his group is currently focused on developing advanced methods for pediatric cardiovascular exams that may improve patient acceptance, while maintaining or improving diagnostic image quality. His group is also focused on developing quantitative imaging methods that can provide insight to changes in cardiovascular structure and function during the progression of disease or in response to pharmacologic therapy. Scientists in his group also work to better understand the risks associated with MRI scanning of patients with implanted devices and technical approaches to mitigating these risks by modifying the MRI exam. Researchers in the Ennis Lab are also developing methods that provide insight to myocardial microstructural remodeling in disease by evaluating changes microstructural organization that can be measured with DT-MRI and evaluated with tensor-field image processing methods. These same studies lend themselves to the building of computational models of cardiac electrophysiology, which can be used to better understand electrical abnormalities of the heart.

近期论文

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Zhou W, Yamakawa K, Benharash P, Ajijola OA, Ennis DB, Hadaya J, Vaseghi M, Shivkumar K, Mahajan A. Effect of Stellate Ganglia Stimulation on Global and Regional Left Ventricular Function Assessed by Speckle Tracking Echocardiography. Am J Physiol Heart Circ Physiol 2013 [PMID 23335795]. Reyhan M, Ennis DB. Quantitative assessment of systolic and diastolic left ventricular twist using Fourier Analysis of Stimulated echoes (FAST) and CSPAMM. J Magn Reson Imaging 2013;37(3):678-683 [PMID 23371791]. Middione MJ, Ennis DB. Chemical shift-induced phase errors in phase-contrast MRI [ISMRM Young Investigator Award Winner]. Magn Reson Med 2013;69(2):391-401 [PMID 22488490]. Zhan L, Jahanshad N, Ennis DB, Jin Y, Bernstein MA, Borowski BJ, Jack CR, Jr., Toga AW, Leow AD, Thompson PM. Angular versus spatial resolution trade-offs for diffusion imaging under time constraints. Hum Brain Mapp 2012 [PMID 22522814]. Wang VY, Ennis DB, Cowan BR, Young AA, Nash MP. Myocardial contractility and regional work throughout the cardiac cycle using FEM and MRI. Proceedings of the Second international conference on Statistical Atlases and Computational Models of the Heart: imaging and modelling challenges. Toronto, ON, Canada: Springer-Verlag;2012. p 149-159. Reyhan M, Natsuaki Y, Ennis DB. Fourier analysis of STimulated echoes (FAST) for the quantitative analysis of left ventricular twist. J Magn Reson Imaging 2012;35(3):587-593 [PMID 22069227]. Moriarty JM, Kung GL, Ramos Y, Moghaddam AN, Ennis DB, Finn JP. Injection of gadolinium contrast through pediatric central venous catheters: a safety study. Pediatr Radiol 2012;42(9):1064-1069 [PMID 22526282]. Langman DA, Goldberg IB, Judy J, Paul Finn J, Ennis DB. The dependence of radiofrequency induced pacemaker lead tip heating on the electrical conductivity of the medium at the lead tip. Magn Reson Med 2012;68(2):606-613 [PMID 22213610]. Langman D, Finn JP, Ennis D. Letters to the Editor. Pacing Clin Electrophysiol 2012 [PMID 22229942]. Itoh A, Stephens EH, Ennis DB, Carlhall CJ, Bothe W, Nguyen TC, Swanson JC, Miller DC, Ingels NB, Jr. Contribution of myocardium overlying the anterolateral papillary muscle to left ventricular deformation. Am J Physiol Heart Circ Physiol 2012;302(1):H180-187 [PMID 22037187].

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