Iglesia, Horacio de la - University of Washington

个人简介

Horacio de la Iglesia finished his undergraduate studies in Biology at the University of Buenos Aires, Argentina. He got his PhD in Neuroscience and Behavior at the University of Massachusetts, Amherst, where working with Eric Bittman he studied the neuroanatomical interactions between the master circadian clock of mammals and the brain centers that control reproduction . He then continued his research on the neural control of circadian rhythms as a Post-doctoral Fellow and as an Instructor in the laboratory of William Schwartz at the University of Massachusetts Medical School. He was also an Instructor at Harvard University where he taught a course on Stem Cells. Dr. de la Iglesia joined the University of Washington Department of Biology in 2003.

研究领域

Our laboratory is interested in understanding how neural systems encode time and generate rhythmic physiological and behavioral outputs to adapt to the temporal structure of the environment. We use a comparative approach that capitalizes on animal models that range from the laboratory mouse to humans. Virtually all living species have biological clocks that generate and control the daily cyclic variations in physiology and behavior, such us the sleep-wake cycle, rhythms in locomotor activity, core body temperature and hormonal secretion. In mammals, the master control of these so-called circadian rhythms is exerted by a biological clock located within the suprachiasmatic nucleus (SCN) of the brain. We use behavioral, physiological and molecular techniques in order to understand how the SCN, in concert with other circadian oscillators in the brain, generates and orchestrates this array of circadian rhythms. We also study human circadian rhthms through non-invasive methods to assess the effect of electric light and the urban environment on the timing and quality of sleep.

近期论文

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Song Song, Jiaguang Zhang (co-first author), Gökalp Gözaydin, Ning Yan* Production of Terephthalic Acid from Corn Stover Lignin Angewandte Chemie, International Edition, Accepted Manuscript (HOT Article) Huiying Yang, Gökalp Gözaydin (co-first author), Ricca Rahman Nasaruddin, Jie Ren Gerald Har, Xi Chen, Xiaonan Wang*, and Ning Yan* Towards the Shell Biorefinery: Processing Crustacean Shell Waste Using Hot Water and Carbonic Acid ACS Sustainable Chemistry and Engineering, Accepted Manuscript Abdelnaby M. Elshahawy , Cao Guan* , Wenjie Zang , Shipeng Ding, Zongkui Kou , Stephen J. Pennycook, Ning Yan , and John Wang*Phospo-oxynitride Layer Protected Cobalt Phosphonitride Nanowire Arrays for High-Rate and Stable Supercapacitators ied Energy Materials, Accepted Manuscript Thuy Trang Pham, Gökalp Gözaydin, Tilo Söhnel, Ning Yan, Jon Sperry* Oxidative Ring-Expansion of a Chitin-Derived Platform Enables Access to Unexplored 2-Aminosugar Chemical Space European Journal of Organic Chemistry, Accepted Manuscript Yunzhu Wang, Shinya Furukawa, Zhang Zhang, Laura Torrente-Murciano, Saif A. A Khan, Ning Yan* Oxidant free conversion of alcohols to nitriles over Ni-based catalysts Catalysis Science and Technology, 2019, 9, 86-96 Ricca Rahman Nasaruddin, Qiaofeng Yao, Tiankai Chen, Max J. Hülsey, Ning Yan*, Jianping Xie* Hydride-Induced Ligand Dynamic and Structural Transformation of Gold Nanoclusters during Catalytic Reaction Nanoscale, 2018, 10, 23113-23121 Yu Zhou, Zhipan Ma (co-first author), Junjie Tang, Ning Yan*, Yonghua Du, Shibo Xi, Kai Wang, Wei Zhang, Haimeng Wen, Jun Wang* Immediate hydroxylation of arenes to phenols via V-containing all-silica ZSM-22 zeolite triggered non-radical mechanism Nature Communications, 2018, 9, 2931 Jiaguang Zhang, Loris Lombardo (co-first author), Gökalp Gözaydin, Paul J. Dyson, Ning Yan* Single-step conversion of lignon monomers to phenol: Bridging the gap between lignin and high-value chemicals Chinese Journal of Catalysis, 2018, 39 (9), 1445-1452 Safak Bulut, Sviatlana Valery Siankevich, Antoine Philippe van Muyden, Duncan Alexander, Georgios Savoglidis, Jiaguang Zhang, Vassily Hatzimanikatis, Ning Yan, Paul Dyson* Efficient cleavage of aryl ether C−O linkages by Rh-Ni and Ru-Ni nanoscale catalysts operating in water hemical Science, 2018, 9, 5530-5535 Max J. Hülsey, Jiaguang Zhang, Ning Yan* Harnessing the Wisdom in Colloidal Chemistry to Make Stable Single-Atom Catalysts Advanced Materials, 2018, 30, 1802304 Song Song, Yunzhu Wang, Ning Yan* A remarkable solvent effect on reductive amination of ketones Molecular Catalysis, 2018, 454, 87-93 Weiping Deng, Yunzhu Wang (co-first author), Sui Zhang, Krishna M. Gupta, Max J. Hülsey, Hiroyuki Asakura, Lingmei Liu, Yu Han, Eric M. Karp, Gregg T. Beckham, Paul J. Dyson, Jianwen Jiang, Tsunehiro Tanaka, Ye Wang and Ning Yan* Catalytic amino acid production from biomass-derived intermediates Proceedings of the National Academy of Sciences, 2018, 115, 5093-5098 Ricca Rahman Nasaruddin, Tiankai Chen, Ning Yan*, Jianping Xie* Roles of thiolate ligands in the synthesis, properties and catalytic application of gold nanoclusters Coordination Chemistry Reviews, 2018, 368, 60-79 Ning Yan*, Karine Philippot* Transformation of CO 2 by using nanoscale metal catalysts: cases studies on the formation of formic acid and dimethylether Current Opinion in Chemical Engineering, 2018, 20, 86-92 Max J. Hülsey, Huiying Yang, Ning Yan* Sustainable Routes for the Synthesis of Renewable Heteroatom-Containing Chemicals ACS Sustainable Chemistry and Engineering, 2018, 6, 5694-5707 Thuy Trang Pham, Xi Chen, Ning Yan, Jonathan Sperry* A novel dihydrodifuropyridine scaffold derived from ketones and the chitin-derived heterocycle 3-acetamido-5-acetylfuran Monatshefte für Chemie - Chemical Monthly, 2018, 149 (4), 857-861 Sudipta De, Maria V. Babak, Max J. Hülsey, Wee Han Ang*, Ning Yan* Designed precursor for the controlled synthesis of highly active atomic and sub-nanometric platinum catalysts on mesoporous silica Chemistry - An Asian Journal, 2018, 13, 1053-1059 Alejandro D. Sadiq, Xi Chen, Ning Yan, Jonathan Sperry* Towards the Shell Biorefinery: Sustainable Synthesis of the Anti-Cancer Alkaloid Proximicin A from Chitin ChemSusChem, 2018, 11, 532 Ricca Rahman Nasaruddin, Tiankai Chen, Jingguo Li, Nirmal Goswami, Jiaguang Zhang, Ning Yan*, Jianping Xie* Ligands modulate reaction pathway in 4-nitrophenol hydrogenation catalyzed by gold nanoclusters ChemCatChem, 2018, 10, 395-402 George Margoutidis, Valerie H. Parsons, Christina S. Bottaro, Ning Yan, Francesca M. Kerton* Mechanochemical Amorphization of α-Chitin and Conversion into Oligomers of N-Acetyl-D-glucosamine ACS Sustainable Chemistry and Engineering, 2018, 6(2), 1662-1669