个人简介
Awards:
Patrick S.C. Poon Endowed Professorship (since 2013)
Natural Science Award (Second Class) by the Ministry of Education (2013)
研究领域
We are interested in the development of inhibitors for bacterial proteins as antimicrobial agents, and the construction of biosensors to screen those inhibitors. Our group is also interested in new materials and catalysts for green chemistry and energy.
近期论文
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Cheung, K.C.; Wong, W.L.; So, M.H.; Zhou, Z.Y.; Yan, S.C.; Wong, K.Y. A Dinuclear Ruthenium Catalyst with Confined Cavity: Selectivity in the Addition of Aliphatic Carboxylic Acids to Phenylacetylene. Chemical Communications, 2013, 49 (7), 710 – 712.
Chan, F.Y.; Sun, N.; Neves, M.A. C.; Lam, P.C.H.; Chung, W.H.; Wong, L.K.; Chow, H.Y.; Ma, D.L.; Chan, P.H.; Leung, Y.C.; Chan, T.H.; Abagyan, R.; Wong, K.Y. Identification of a New Class of FtsZ Inhibitors by Structure-Based Design and in Vitro Screening. Journal of Chemical Information and Modeling, 2013, 53(8), 2131-2140.
Ha, E.; Lee, L.Y.S.; Wang, J.; Li, F.; Wong, K.Y.; Tsang, S.C.E. Significant Enhancement in Photocatalytic Reduction of Water to Hydrogen by Au/Cu2ZnSnS4 Advanced Materials, 2014, 26 (21), 3496-3500.
Wang, Y.; Chan, F.Y.; Sun, N.; Lui, H. K.; So, P.K.; Yan, S.C.; Chan, K.F.; Chiou, J.; Chen, S.; Abagyan, R.; Leung, Y.C.; Wong, K.Y. Structure-based Design, Synthesis, and Biological Evaluation of Insatin Derivatives as Potential Glycosyltransferase Inhibitors. Chemical Biology and Drug Design, 2014, 84(6), 685-696.
Chan, F.Y.; Sun, N.; Leung, Y.C.; Wong, K.Y. Antimicrobial activity of a quinuclidine-based FtsZ inhibitor and its synergistic potential with β-lactam antibiotics. The Journal of Antibiotics, 2015, 68(4), 253-258.
Ha, E.; Lee, L.Y.S.; Man, H.W.; Tsang, S.C.E.; Wong, K.Y. Morphology-Controlled Synthesis of Au/Cu2FeSnS4 Core-Shell Nanostructures for Plasmon-Enhanced Photocatalytic Hydrogen Generation. ACS Applied Materials & Interfaces, 2015, 7(17), 9072-9077.
Peng, X.; Hu, L.; Wang, L.; Zhang, X.; Fu, J.; Huo, K.; Lee, L.Y.S.; Wong, K.Y.; Chu, P.K. Vanadium carbide nanoparticles encapsulated in graphitic carbon network nanosheets: A high-efficiency electrocatalyst for hydrogen evolution reaction. Nano Energy, 2016, 26, 603-609.
Hu, ; Yap, H.K.; Fung, Y.H.; Wang, Y.; Cheong, W.L.; So, L.Y.; Tsang, C.S.; Lee, L.Y.S.; Lo, W.K.C.; Yuan, J.; Sun, N.; Leung, Y.C.; Yang, G.; Wong, K.Y. Light up' protein-protein interaction through bioorthogonal incorporation of a turn-on fluorescent probe into β-lactamase. Molecular BioSystems, 2016, 12(12),3544-3549.
Sun, N.; Lu, Y.J.; Chan, F.Y.; Du, R.L.; Zheng, Y.Y.; Zhang, K.; So, L.Y.; Abagyan, R.; Zhuo, C.; Leung, Y.C.; Wong, K.Y. A Thiazole Orange Derivative Targeting the Bacterial Protein FtsZ Shows Potent Antibacterial Activity. Frontiers in Microbiology, 2017, 8, 855.
Zhu, Jing; Ha, Enna; Zhao, Guoliang; Zhou, Yang; Huang, Deshun; Yue, Guozong; Hu, Liangsheng; Sun, Ning; Wang, Yong; Lee, Lawrence Yoon Suk; Xu, Chen; Wong, Kwok-Yin; Astruc, Didier; Zhao, Pengxiang. Recent advance in MXenes: A promising 2D material for catalysis, sensor and chemical adsorption Coordination Chemistry Reviews, 2017, 352, 306-327.