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Molecular genetics detoxification mechanisms in bacteria and flies; insecticide and antibiotic resistance.

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Syvanen, M., Z. Zhou, J. Wharton, C. Goldsbury, A. Clark. Heterogeneity of the glutathione transferase genes encoding enzymes responsible for insecticide degradation in the housefly. J. Molec. Evol. 1996 Sep;43:236-240. Zhou, Z. and M. Syvanen. A complex glutathione transferase gene family in the housefly Musca domestica. Molecular and General Genetics, 1997 Sep;256:187-194. Syvanen, M. Insertion sequences and their evolutionary role. In: Bacterial Genomes, Physical Structure and Analysis, 1998 F. deBruijn, J.R. Lupski, G.M. Weinstock (eds.), Chapman-Hall, Chapter 20, pg. 213-220. Turner, K.O., M. Syvanen and S. Meizel. The human acrosome reaction is highly sensitive to inhibition by cyclodiene insecticides. Journal of Andrology, 1997 Nov-Dec;18:571-575. Syvanen, M. and C. Kado, editors, Horizontal Gene Transfer, 1998 Chapman & Hall, London. 474 pgs. Syvanen, M. Temporal patterns of land plant evolution suggest extensive polyphyly. 1999 Pp. 376-386, In: From Symbiosis to Eukaryotism-Endocytobiology VII, (eds. Wagner, E., Normann, J., Greppin, H., Hackstein, J.H.P., Herrmann, R.G., Kowallik, K.v., Schenk, H.E.A., and Seckbach, J.), Geneva University Press. Syvanen, M. and C. Kado eds. Horizontal Gene Transfer (2nd Edition), 2002 Academic Press, New York, London 445 pp. Syvanen, M. Temporal patterns of eukaryotic evolution suggest extensive polyphyly. In: Horizontal Gene Transfer (2nd Edition), 2002 Academic Press, New York, London. pp 383-395. Syvanen, M. On the occurrence of horizontal gene transfer among an arbitrarily chosen group of 26 genes. Journal of Molecular Evolution. 2002 Feb;54:258-66 Syvanen M. Rates of Ribosomal RNA Evolution Are Uniquely Accelerated in Eukaryotes. J. Mol. Evol. 2002 Jul;55:85-91. Syanen, M. Recent emergence of the modern genetic code: a proposal. Trends Genet. 2002 May;18 (5): 245-8. Syvanen, M. Churning out safer microbes for drug delivery, Nat Biotechnol. 2003 Jul;21(7):758-9. Syvanen, M. Modification of Helicobacter pylori outer membrane protein expression during experimental infection of rhesus macaques. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):2106-11. Syvanen, M. Transcription profile of Helicobacter pylori in the human stomach reflects its physiology in vivo. J Infect Dis. 2004 Sep 1;190(5):946-56.

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