Kaysen, George A. - University of California, Davis - Department of Biochemistry and Molecular Medicine

研究领域

Roles of nutrition and inflammation in establishing plasma protein composition and body composition in humans. Albumin metabolism in nephrotic syndrome; regulation of hepatic gene express. Mechanism of hyperlipidemia in renal disease, consequence and cause of inflammation in dialysis, effects of inflammation on vascular endothelial structure and function, regulation of plasma protein composition.

近期论文

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Lower C-reactive protein and better hemodialysis survival are associated with regular exercise activity: Longitudinal outcomes from the ACTIVE-ADIPOSE special study. Kutner NG, Zhang R, Huang Y, Kaysen GA, Park J. Hemodial Int. 2016 Jul;20(3):473-83. doi: 10.1111/hdi.12408. PMID: 2695472 Associations of Trimethylamine N-Oxide With Nutritional and Inflammatory Biomarkers and Cardiovascular Outcomes in Patients New to Dialysis. Kaysen GA, Johansen KL, Chertow GM, Dalrymple LS, Kornak J, Grimes B, Dwyer T, Chassy AW, Fiehn O. J Ren Nutr. 2015 Jul;25(4):351-6. doi: 10.1053/j.jrn.2015.02.006. PMID: 25802017 Agreement of single- and multi-frequency bioimpedance measurements in hemodialysis patients: an ancillary study of the Frequent Hemodialysis Network Daily Trial. Raimann JG, Abbas SR, Liu L, Zhu F, Larive B, Kotanko P, Levin NW, Kaysen GA; FHN Trial.. Nephron Clin Pract. 2014;128(1-2):115-26. doi: 10.1159/000366447. PMID: 25402657 Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial. Langefeld CD, Divers J, Pajewski NM, Hawfield AT, Reboussin DM, Bild DE, Kaysen GA, Kimmel PL, Raj DS, Ricardo AC, Wright JT Jr, Sedor JR, Rocco MV, Freedman BI; Systolic Blood Pressure Intervention Trial (SPRINT).. Kidney Int. 2015 Jan;87(1):169-75. doi: 10.1038/ki.2014.254. PMID: 25029429 Effect of change in fluid distribution in segments in hemodialysis patients at different ultrafiltration rates on accuracy of whole body bioimpedance measurement. Abbas SR, Zhu F, Kaysen GA, Kotanko P, Levin NW. J Appl Physiol (1985). 2014 Jun 1;116(11):1382-9. doi: 10.1152/japplphysiol.01361.2013. PMID: 24674858 Association between body composition and frailty among prevalent hemodialysis patients: a US Renal Data System special study. Johansen KL, Dalrymple LS, Delgado C, Kaysen GA, Kornak J, Grimes B, Chertow GM. J Am Soc Nephrol. 2014 Feb;25(2):381-9. doi: 10.1681/ASN.2013040431. PMID: 2415898 Comparison of fluid volume estimates in chronic hemodialysis patients by bioimpedance, direct isotopic, and dilution methods. Raimann JG, Zhu F, Wang J, Thijssen S, Kuhlmann MK, Kotanko P, Levin NW, Kaysen GA. Kidney Int. 2014 Apr;85(4):898-908. doi: 10.1038/ki.2013.358. PMID: 24067432 Changes in serum inflammatory markers are associated with changes in apolipoprotein A1 but not B after the initiation of dialysis. Kaysen GA, Dalrymple LS, Grimes B, Chertow GM, Kornak J, Johansen KL. Nephrol Dial Transplant. 2014 Feb;29(2):430-7. doi: 10.1093/ndt/gft370. PMID: 24009290 Comparison of bioimpedance and dual-energy x-ray absorptiometry for measurement of fat mass in hemodialysis patients. Molfino A, Don BR, Kaysen GA. Nephron Clin Pract. 2012;122(3-4):127-33. doi: 10.1159/000350817. PMID: 23689544 Prealbumin is associated with visceral fat mass in patients receiving hemodialysis. Molfino A, Heymsfield SB, Zhu F, Kotanko P, Levin NW, Dwyer T, Kaysen GA. J Ren Nutr. 2013 Nov;23(6):406-10. doi: 10.1053/j.jrn.2013.02.007. PMID: 23623396 Modeling time-varying effects with generalized and unsynchronized longitudinal data. Şentürk D, Dalrymple LS, Mohammed SM, Kaysen GA, Nguyen DV. Stat Med. 2013 Jul 30;32(17):2971-87. doi: 10.1002/sim.5740. PMID: 23335196 Association of physical activity with survival among ambulatory patients on dialysis: the Comprehensive Dialysis Study. Johansen KL, Kaysen GA, Dalrymple LS, Grimes BA, Glidden DV, Anand S, Chertow GM. Clin J Am Soc Nephrol. 2013 Feb;8(2):248-53. doi: 10.2215/CJN.08560812. PMID: 23124787 Longitudinal measures of serum albumin and prealbumin concentrations in incident dialysis patients: the comprehensive dialysis study. Dalrymple LS, Johansen KL, Chertow GM, Grimes B, Anand S, McCulloch CE, Kaysen GA. J Ren Nutr. 2013 Mar;23(2):91-7. doi: 10.1053/j.jrn.2012.03.001. PMID: 22633987 The effect of frequent hemodialysis on nutrition and body composition: frequent Hemodialysis Network Trial. Kaysen GA, Greene T, Larive B, Mehta RL, Lindsay RM, Depner TA, Hall YN, Daugirdas JT, Chertow GM; FHN Trial Group..Kidney Int. 2012 Jul;82(1):90-9. doi: 10.1038/ki.2012.75. PMID: 22456602 Effects of six versus three times per week hemodialysis on physical performance, health, and functioning: Frequent Hemodialysis Network (FHN) randomized trials. Hall YN, Larive B, Painter P, Kaysen GA, Lindsay RM, Nissenson AR, Unruh ML, Rocco MV, Chertow GM; Frequent Hemodialysis Network Trial Group.. Clin J Am Soc Nephrol. 2012 May;7(5):782-94. doi: 10.2215/CJN.10601011. PMID: 22422538 Risk of cardiovascular events after infection-related hospitalizations in older patients on dialysis.Dalrymple LS, Mohammed SM, Mu Y, Johansen KL, Chertow GM, Grimes B, Kaysen GA, Nguyen DV. Clin J Am Soc Nephrol. 2011 Jul;6(7):1708-13. doi: 10.2215/CJN.10151110. PMID: 21566109 Kaysen GA. Lipid and lipoprotein metabolism in chronic kidney disease. J Ren Nutr, 2009. 19(1): 73-7. Kaysen GA. New insights into lipid metabolism in chronic kidney disease: what are the practical implications? Blood Purif, 2009. 27(1): 86-91. Kutner NG, Johansen KL, Kaysen GA, Pederson S, Chen SC, Agodoa LY, Eggers PW, Chertow GM. The comprehensive dialysis study (CDS): a USRDS special study. Clin J Am Soc Nephrol, 2009. 4(3): 645-50. Anderson S, Halter JB, Hazzard WR, Himmelfarb J, Horne FM, Kaysen GA, Kusek JW, Nayfield SG, Schmader K, Tian Y, Ashworth JR, Clayton CP, Parker RP, Tarver ED, Woolard NF, High KP,. Prediction, progression, and outcomes of chronic kidney disease in older adults. J Am Soc Nephrol, 2009. 20(6): 1199-209. Kaysen GA. Potential restoration of HDL function with apolipoprotein A-I mimetic peptide in end-stage renal disease. Kidney Int, 2009. 76(4): 359-61. Kaysen GA, Kotanko P, Zhu F, Sarkar SR, Heymsfield SB, Kuhlmann MK, Dwyer T, Usvyat L, Havel P, Levin NW. Relationship between adiposity and cardiovascular risk factors in prevalent hemodialysis patients. J Ren Nutr, 2009. 19(5): 357-64. Hsu J, Johansen KL, Hsu CY, Kaysen GA, Chertow GM. Higher serum creatinine concentrations in black patients with chronic kidney disease: beyond nutritional status and body composition. Clin J Am Soc Nephrol, 2008. 3(4): 992-7. Kaysen GA, Kotanko P, Zhu F ,Sarkar S, Heymsfield SB, Kuhlmann MK, Levin NW. Estimation of adipose pools in hemodialysis patients from anthropometric measures. J Renal Nutrition. 2008.