Ristenpart, William - University of California, Davis - Department of Chemical Engineering

个人简介

B.S. 1999, University of California, Davis Ph. D. 2005, Princeton University

研究领域

High speed imaging of charge transfer events in drops CAREER Award, National Science Foundation (CBET) The main scientific goal of this research is to answer the question: how do droplets acquire charge? Recent work by the PI has revealed the existence of a critical electric charge density above which oppositely charged drops do not coalesce (Ristenpart et al., Nature 2009). Strikingly, there are no extant models that accurately predict the amount of charge transferred to a liquid drop upon contact with an electrified surface. Our experimental framework allows groundbreaking, fundamental studies of charge transfer dynamics in emulsions by combining simultaneous high- speed visualization and chronocoulometric techniques. Influence of Oxidative Stress on Shear-Induced Mechanotransduction in Red Blood Cells Current support: NIH DEB Fellowship The main scientific goal of this proposal is to answer the question: how does oxidative stress affect the response of red blood cells to shear stress? Recent work by the PI and colleagues has established an in vitro microfluidic technique for probing how blood cells respond to sudden changes in shear stress (Wan et al., PNAS 2008). Oxidative chemicals are known to affect the `fluidity’ of red blood cell membranes, but little is known about their influence on the dynamic response to changes in shear stress. This research allows fundamental studies of the dynamics of shear-induced deformations in red blood cells under conditions of oxidative stress.

近期论文

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B. Hamlin and W. D. Ristenpart, “Transient reduction of the drag coefficient of charged droplets via the convective reversal of stagnant caps,” Physics of Fluids 24, 012101 (2012). W. D. Ristenpart & H. A. Stone, “Michaelis-Menten kinetics in shear flow: Similarity solutions for multi-stepreactions,” Biomicrofluidics 6, 014108 (2012). S. Asavasanti, P. Stroeve, D. M. Barrett, and W. D. Ristenpart, “Enhanced electroporation in plant tissues via low frequency pulsed electric fields: Influence of cytoplasmic streaming,” Biotechnology Progress, in press Q. Zhou, W. D. Ristenpart, P. Stroeve, “Magnetically induced decrease in droplet contact angle on nanostructured surfaces,” Langmuir 27, 11747-11571 (2011). S. Asavasanti, W. D. Ristenpart, P. Stroeve, and D. M. Barrett, “Permeabilization of plant tissues bymonopolar pulsed electric fields: Effect of frequency,” Journal of Food Science 76, 98-111 (2011). A. G. Bick, W. D. Ristenpart, E. van Nierop, and H. A. Stone, “Mechanical inhibition of foam formation via arotating nozzle,” Journal of Fluids Engineering 133, 044503 (2011). S. Asavasanti, S. Ersus, W. D. Ristenpart, P. Stroeve, and D. M. Barrett, “Critical electric field strengths of onion tissues treated by pulsed electric fields,” Journal of Food Science 75, 433-443 (2010). C. R. Vigo and W. D. Ristenpart, “Aggregation and coalescence of oil droplets via electrohydrodynamic flows,” Langmuir 26, 10703-10707 (2010). A. M. Forsyth, J. D. Wan, W. D. Ristenpart, and H. A. Stone, “The dynamic behavior of chemically ‘stiffened’ red blood cells in microchannel flows,” Microvascular Research 80, 37-43 (2010). W. D. Ristenpart, O. Vincent, S. Lecuyer and H. A. Stone, “Dynamic angular segregation of vesicles in electrohydrodynamic flows,” Langmuir 26, 9429-9436 (2010).