Gomes, Aldrin - University of California, Davis - College of Biological Sciences

研究领域

Muscle Physiology and Proteomics Laboratory

近期论文

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Gilda JE, Lai X, Witzmann FA, Gomes AV. (2016) Delineation of molecular pathways involved in cardiomyopathies caused by troponin T mutations. Molecular and Cellular Proteomics. 15(6):1962-81. Ghosh R, Hwang SM, Cui Z, Gilda JE, Gomes AV. (2016) Different effects of the nonsteroidal anti-inflammatory drugs meclofenamate sodium and naproxen sodium on proteasome activity in cardiac cells. Journal of Molecular and Cellular Cardiology. 94:131-144. Ghosh R, Goswami SK, Feitoza LF, Hammock B, Gomes AV. (2016) Diclofenac induces proteasome and mitochondrial dysfunction in murine cardiomyocytes and hearts. Int J Cardiol. 223:923-935. Landry M, Gomes AV. (2016) Antibodies: Half of samples fail protein-blot tests. Nature. 529(7584):25 Gilda JE, Xu Q, Martinez ME, Nguyen ST, Chase PB, Gomes AV. (2016) The functional significance of the last 5 residues of the C-terminus of cardiac troponin I. Arch Biochem Biophys. 601:88-96. West DW, Baehr LM, Marcotte GR, Chason CM, Tolento L, Gomes AV, Bodine SC, Baar K. (2016) Acute resistance exercise activates rapamycin-sensitive and -insensitive mechanisms that control translational activity and capacity in skeletal muscle. J Physiol. 15;594(2):453-68. Klionsky DJ et al. (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12(1):1-222. Lindsey ML, Mayr M, Gomes AV, Delles C, Arrell DK, Murphy AM, Lange RA, Costello CE, Jin YF, Laskowitz DT, Sam F, Terzic A, Van Eyk J, Srinivas PR; (2015) Transformative Impact of Proteomics on Cardiovascular Health and Disease: A Scientific Statement From the American Heart Association. AHA Council on Functional Genomics and Translational Biology, Council on Cardiovascular Disease in the Young, Council on Clinical Cardiology, Council on Cardiovascular and Stroke Nursing, Council on Hypertension, and Stroke Council. Circulation. 132(9):852-72. Gomes AV, Kazmierczak K, Cheah JX, Gilda JE, Yuan CC, Zhou Z, Szczesna-Cordary D. (2015) Proteomic analysis of physiological versus pathological cardiac remodeling in animal models expressing mutations in myosin essential light chains. J Muscle Res Cell Motil. 36(6):447-61. Gilda JE, Ghosh R, Cheah JX, West TM, Bodine SC, Gomes AV. (2015) Western Blotting Inaccuracies with Unverified Antibodies: Need for a Western Blotting Minimal Reporting Standard (WBMRS). PLoS One. 2015 10(8):e0135392. Carbonell T, Gomes AV. (2015) Dynamic regulation of the proteasome by systolic overload. Journal of Molecular and Cellular Cardiology 87:1-3. Negroni JA, Morotti S, Lascano EC, Gomes AV, Grandi E, Puglisi JL, Bers DM. (2015) β-adrenergic effects on cardiac myofilaments and contraction in an integrated rabbit ventricular myocyte model. Journal of Molecular and Cellular Cardiology 81:162-75. Gomes AV, Rajasekaran NS, Pi X. (2015) Redox Signaling and the Cardiovascular and Skeletal Muscle System. Oxid Med Cell Longev. 2015:849095. Ghosh R, Alajbegovic A, Gomes AV. (2015) NSAIDs and Cardiovascular Diseases: Role of Reactive Oxygen Species. Oxidative Medicine and Cellular Longevity. 2015:536962. Gilda JE, Gomes AV. (2015) Western blotting using in-gel protein labeling as a normalization control: stain-free technology. Methods Mol Biol. 1295: 381 -91. Jamart C, Gomes AV, Dewey S, Deldicque L, Raymackers JM, Francaux M. (2014) Regulation of ubiquitin-proteasome and autophagy pathways after acute LPS and epoxomicin administration in mice. BMC Musculoskelet Disord.15:166. Ghosh R, Gilda JE, Gomes AV. (2014) The necessity of and strategies for improving confidence in the accuracy of western blots. Expert Rev Proteomics. 11(5):549-60. Cui, Z., Scruggs, S.B., Gilda, J.E., Ping, P., Gomes, A.V. (2014) Regulation of cardiac proteasomes by ubiquitination, SUMOylation, and beyond. J Mol Cell Cardiol. 71:32-42. Cui, Z., Hwang, S.M., and Gomes A.V. (2014) Identification of the immunoproteasome as a novel regulator of skeletal muscle differentiation. Mol Cell Biol. 34(1):96-109. Narashimhan M., Hong J., Atieno N., Muthusamy V.R., Davidson C.J., Abu-Rmaileh N., Richardson R., Gomes A.V., Hoidal J.R., Rajasekaran N.S. (2014) Nrf2 Deficiency Promotes Apoptosis and Impairs Pax7/MyoD Expression in Aging Skeletal Muscle Cells. Free Radical Biology and Medicine. 71:402-14. Wecksler A.T., Hwang S.H., Wettersten H.I., Gilda J.E., Patton A., Leon L.J., Carraway K.L. 3rd, Gomes A.V, Baar K., Weiss R.H., Hammock B.D. (2014) Novel sorafenib-based structural analogues: in-vitro anticancer evaluation of t-MTUCB and t-AUCMB. Anticancer Drugs. 25(4):433-46. Puglisi JL, Goldspink PH, Gomes AV, Utter MS, Bers DM, Solaro RJ. (2014) Influence of a constitutive increase in myofilament calcium-sensitivity on calcium-fluxes and contraction of mouse heart ventricular myocytes. Arch Biochem Biophys. 15;552-553 Domenighetti AA, Chu PH, Wu T, Sheikh F, Gokhin DS, Guo LT, Cui Z, Peter AK, Christodoulou DC, Parfenov MG, Gorham JM, Li DY, Banerjee I, Lai X, Witzmann FA, Seidman CE, Seidman JG, Gomes AV, Shelton GD, Lieber RL, Chen J. (2014) Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice. Human Molecular Genetics. 23(1):209-225. Cui Z, Gilda JE, Gomes AV. (2014) Crude and purified proteasome activity assays are affected by type of microplate. Anal Biochem. 446: 44–52. Dewey, S., Lai, X., Witzmann,F., Sohal, M., Gomes, A.V. (2013) Proteomic Analysis of Hearts from Akita Mice Suggests Increases in Soluble Epoxide Hydrolase and Antioxidative Programming are Key Changes in Early Stages of Diabetic Cardiomyopathy. Journal of Proteome Research, 12(9): 3920–3933.