Powers, Ted - University of California, Davis - College of Biological Sciences

研究领域

Signal Transduction and Cell Growth Control

近期论文

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Vlahakis, A., Lopez Muniozguren, N., and Powers, T. (2017) Mitochondrial respiration links TOR Complex 2 signaling to calcium regulation and autophagy. Autophagy (in press) DOI 10.1080/15548627.2017.1299314 Vlahakis, A., Lopez Muniozguren, N., and Powers, T. (2016) Calcium channel regulator Mid1 links TORC2-mediated changes in mitochondrial respiration to autophagy. J. Cell Biol. 215, 779-788. Klionsky, D., et al (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12, 1554-8627. Stauffer, B. and Powers, T. (2016) Target of rapamycin signaling mediates vacuolar fragmentation. Current Genetics (in press) DOI 10.1007/s00294-016-0616-0 Stauffer, B. and Powers, T. (2015) Target of rapamycin signaling mediates vacuolar fission caused by endoplasmic reticulum stress in S. cerevisiae. Mol. Bio. Cell 26, 4618-4630 . Fresques, T., Niles, B., Aronova, S., Mogri, H., Rakhshandehroo, T., and Powers, T. (2015) Regulation of ceramide synthase by casein kinase 2-dependent phosphorylation in S. cerevisiae. J. Biol. Chem. 290, 1395-1403. Vlahakis, A. and Powers, T. (2014) A role for TOR complex 2 signaling in promoting autophagy. Autophagy 10, 2085-2086. Niles, B.J. and Powers, T. (2014) TOR Complex 2-Ypk1 signaling regulates actin polarization via reactive oxygen species (ROS). Mol. Biol. Cell 25, 3962-3972. Vlahakis, A., Graef, M., Nunnari, J., and Powers, T. (2014) TOR complex 2-Ypk1 signaling is an essential positive regulator of the general amino acid control response and autophagy. Proc Natl Acad Sci USA 111, 10586-10591. Niles, B.J., Joslin, A.C., Fresques, T., and Powers, T. (2014) TOR Complex 2-Ypk1 signaling maintains sphingolipid homeostasis by sensing and regulating ROS accumulation. Cell Reports, 6, 541-552. Niles, B.J. & Powers, T. (2012) Plasma membrane proteins Slm1 and Slm2 mediate activation of the AGC kinase Ypk1 by TORC2 and sphingolipids in S. cerevisiae. Cell Cycle 11, 3745-3749 Niles, B.J., Mogri, H., Hill, A., Vlahakis, A., and Powers, T. (2012) Plasma membrane recruitment and activation of the AGC kinase Ypk1 is mediated by target of rapamycin complex 2 (TORC2) and its effector proteins Slm1 and Slm2. Proc. Natl Acad Sci USA 109, 1536-1541 Liu, Q, Ren, T, Fresques, T, Oppliger, W, Niles, BJ, Hur, W, Sabatini, DM, Hall, MN, Powers, T, Gray, NS. (2012) Selective ATP-Competitive Inhibitors of TOR Suppress Rapamycin-Insensitive Function of TORC2 in Saccharomyces cerevisiae. ACS chemical biology, 7(6): 982-7. Powers, T., Arovona, S, and Niles, B. (2010) TORC2 and sphingolipid biosynthesis: Lessons from budding yeast. The Enzymes, Vol. XXVII, 177-197. Powers, T. (2008) Cell growth control: mTOR takes on fat. Mol. Cell 31, 775-776 Aronova, S., Wedaman, K., Aronov, P.A., Fontes, K., Ramos, K., Hammock, B.D., and Powers, T. (2008) Regulation of ceramide biosynthesis by TOR Complex 2. Cell Metabolism 7, 148-158. Powers, T. (2007) TOR Signaling and S6 Kinase 1: Yeast Catches Up. Cell Metabolism 6, 1-2. Aronova, S., Wedaman, K.P., Anderson, S., Yates, J. III, and Powers, T. (2007) Probing the membrane environment of the TOR kinases reveals functional interactions between TORC1, actin, and membrane trafficking in S. cerevisae. Mol. Biol. Cell 18, 2779-2794. Martin, D.E., Powers, T., and Hall, M.N. (2006) Regulation of ribosome biogenesis; Where is TOR? Cell Metabolism 4, 259-260. Reinke, A., Chen, J.C.-Y., Aronova, S., and Powers, T. (2006) Caffeine targets TOR complex I and provides evidence for a regulatory link between the FRB and kinase domains of Tor1p. J. Biol. Chem. 281, 31616-31626. Chen, C.-Y. & Powers, T. (2006) Coordinate regulation of multiple and distinct biosynthetic pathways by TOR and PKA kinases in S. cerevisiae. Current Genetics 49, 281-293 Dilova, I. & Powers, T. (2006) Accounting for strain-specific differences during RTG target gene regulation in Saccharomyces cerevisiae. FEMS Yeast Research Jan 6(1):112-9. Powers, T. (2004) Ribosome biogenesis: Giant steps for a giant problem. Cell 119, 901-902. Powers T, Dilova I, Chen CY, Wedaman K (2004) Yeast TOR signaling: a mechanism for metabolic regulation. Curr Top Microbiol Immunol. 279, 39-51 Powers, T., Chen, C.-Y., Dilova, D., Reinke, A., and Wedaman, K.P. (2004) Tor-signaling and Tor-interacting proteins in yeast. Topics in Current Genetics 7, 201-223.