Nunnari, Jodi - University of California, Davis - College of Biological Sciences

研究领域

My laboratory is interested in the mechanisms that govern the behavior of mitochondria in cells.

近期论文

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Hoppins S and Nunnari J. (2012) Mitochondrial dynamics and apoptosis--the ER connection. Science. 337:1052-4 Lackner LL, Ping H, Graef M, Murley A, Nunnari J. (2013) Endoplasmic reticulum-associated mitochondria-cortex tether functions in the distribution and inheritance of mitochondria. Proc Natl Acad Sci U S A. 110:E458-67. Murley A, Lackner LL, Osman C, West M, Voeltz GK, Walter P, Nunnari J. (2013) ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast. eLife May 14 Meeusen, S., McCaffrey, J.M., and Nunnari, J. (2004) Mitochondrial fusion intermediates revealed in vitro. Science, 305:1747-52 Ingerman E, Perkins EM, Marino M, Mears JA, McCaffery JM, Hinshaw JE, Nunnari J. Dnm1 forms spirals that are structurally tailored to fit mitochondria. J Cell Biol. 2005 Sep 26;170(7):1021-7. Meeusen S, DeVay R, Block J, Cassidy-Stone A, Wayson S, McCaffery JM, Nunnari J. Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1. Cell. 2006 Oct 20;127(2):383-95. Hoppins, S., Lackner, L. and Nunnari, J. 2007 The machines that fuse and divide mitochondria. Annual Review of Biochemistry, 76: 751-80. Cassidy-Stone, A., Chipuk, J.E., Ingerman, E., Song, C., Yoo, C., Kuwana, T., Kurth, M.J., Shaw. J., Hinshaw. J.E., Green, D.R., and Nunnari, J. 2008 Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak dependent mitochondrial outer membrane permeabilization. Developmental Cell, 14:193-204. Kornmann B, Currie E, Collins SR, Schuldiner M, Nunnari J, Weissman JS, Walter P. (2009) An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science 325:477-81. Lacker, LL, Horner, J and Nunnari, J. (2009) Mechanistic analysis of a dynamin effector, Science, 325(5942):874-7. Hoppins, S, Edlich, F., Cleland, M. Banerjee, S., McCaffery, J.M., Youle, R. and Nunnari J. (2011) The soluble form of Bax regulates fusion via MFN2 homotypic complexes. Molecular Cell, 41:150-60. Graef M. and Nunnari J. (2011)Mitochondria regulate autophagy by conserved signaling pathways. EMBO J. 30 2101-14 Friedman J.R., Lackner L.L., West M., DiBenedetto J.R., Nunnari J. and Voeltz, G. (2011) ER tubules mark sites of mitochondrial division. Science 334(6054) 358-62 Ford M.G.J., Jenni S. and Nunnari J. (2011) The crystal structure of dynamin. Nature 477 561-6 Hoppins S., Collins S.R., Cassidy-Stone A., Hummel E., DeVay R.M., Lackner L.L., Westermann B., Schuldiner M., Weissman J.S. and Nunnari J. (2011) A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. J. Cell Biol. 195(2) 323-40 Nunnari J. and Suomalainen A. (2012) Mitochondria: in sickness and in health. Cell 148 1145-59