Recanzone, Gregg - University of California, Davis

研究领域

Our research involves investigating the role of the cerebral cortex in the perception of auditory signals, with a current emphasis on the effects of aging. Age-related hearing deficits affect the majority of American retirees, and virtually all Americans over the age of 75. These deficits go beyond a simple loss of hearing, but also result in a poor ability to tell where different sounds are coming from, and in understanding speech. Our research investigates how natural aging affects the cerebral cortex, the neural structure that is necessary for one to perceive, and appreciate, different sound qualities. Our ultimate objective is to better understand cortical processing mechanisms in young and aged brains in order to develop effective remedial therapies to circumvent age-related hearing loss.

近期论文

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Ng, C.W., Navarro, X.O., Engle, J.R. and Recanzone, G.H. (2015) Age-related changes of auditory brainstem responses in non-human primates. J. Neurophysiol. 114:455-467. Gray, D.T., Engle, J.R. and Recanzone, G.H. (2014) Age-related neurochemical changes in the rhesus macaque cochlear nucleus. J. Comp. Neurol. 522:1527-1541. Gray, D.T., Engle, J.R., Rudolph, M.L. and Recanzone, G.H. (2014) Regional and age-related differences in GAD67 expression of parvalbumin0 and calbindin-expressing neurnos in teh rhesus macaque auditory midbrain and brainstem. J. Comp. Neurol. 522:4074-4084. Engle, J.R., Tinling, S. and Recanzone, G.H. (2013) Age-related hearing loss in rhesus monkeys is correlated with cochlear histopathologies. PLoS One e55092. Engle, J.R. and Recanzone, G.H. (2013) Characterizing spatial tuning functions of neurons in the auditory cortex of young and aged monkeys: a new perspective on old data. Front. Aging Neurosci. 4:36. Gray, D.T., Engle, J.R. and Recanzone, G.H. (2013) Age-related neurochemical changs in teh rhesus macaque superior olivary complex. J. Comp. Neurol. 522:573-591. Recanzone, G.H., Engle, J.R. and Juarez-Salinas, D.L. (2011) Spatial and temporal processing of single auditory cortical neurons and populations of neurons in the macaque monkey. Hear. Res. 271:115-22. Recanzone, G.H. (2011) Perception of auditory signals. Ann. N.Y.Acad. Sci. 1224:96-108. Juarez-Salinas D.L., Engle J.R., Navarro X.O. and Recanzone, G.H. (2010) Hierarchical and serial processing in the spatial auditory cortical pathway is degraded by natural aging. J. Neurosci. 30:14795-804. Recanzone, G.H. and Cohen, Y.E. (2010) Serial and parallel processing in the primate auditory cortex revisited. Beh. Brain Res. 206:1-7. Miller, L.M., and Recanzone, G.H.(2009) Populations of auditory cortical neurons can accurately encode acoustic space across stimulus intensity. Proc. Natl. Acad. Sci. 106:5931-5. Recanzone, G.H. (2009) Interactions of auditory and visual stimuli in space and time. Hear Res. 258:89-99.