Ekstrom, Arne - University of California, Davis - College of Biological Sciences

研究领域

The primary mission of the lab is to better understand the neurophysiological basis of human memory. Our particular focus is on spatial memory and attempting to understand the cognitive and neural components underlying it. We employ several different recording methodologies to better understand spatial memory, including intracranial EEG, fMRI, and scalp EEG. Studies in the lab focus on how human hippocampal theta oscillations code for aspects of a spatial layout, which brain areas are involved in overview and first-person representations, how navigation and memory processing are represented in overlapping or unique brain systems, and how the different recording modalities we use tie together or provide complementary information about underlying brain processes.

近期论文

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Ekstrom AD. (2010) How and when the fMRI BOLD signal relates to underlying neural activity: The danger in dissociation. Brain Research Reviews, 62(2):233-44. PMID: 20026191. Ekstrom AD, Bazih AJ, Suthana NA, Al-Hakim R, Ogura K, Zeineh M, & Bookheimer SY. (2009). Advances in High-Resolution Imaging and Computational Unfolding of the Human Hippocampus. Neuroimage. 47, 42-49. PMID: 19303448. Suthana NA, Ekstrom AD, Moshirvaziri S, Knowlton B, & Bookheimer, SY. (2009). Human Hippocampal CA1 Involvement During Allocentric Encoding of Spatial Information. Journal of Neuroscience, 26, 10512-10519. PMID: 19710304. Ekstrom AD, Suthana NA, Millet D, Fried I, & Bookheimer SY. (2009). Correlation Between BOLD fMRI and Theta-band Local Field Potentials In the Human Hippocampal Area. Journal of Neurophysiology, 101, 2668-2678. PMID: 19244353. Ekstrom AD and Bookheimer SY. (2007). Spatial and Temporal Episodic Memory Retrieval Recruit Dissociable Functional Networks in the Human Brain. Learning and Memory, 14, 645-654. PMID: 17893237. Ekstrom AD, Kahana MJ, Caplan JB, Fields TA, Isham EA, Newman E, & Fried I. (2003). Cellular Networks Underlying Human Spatial Navigation. Nature, 425, 184-188. PMID: 12968182. Ekstrom AD, Meltzer J, McNaughton BL, & Barnes CA. (2001). NMDA Receptor Antagonism Blocks Experience-Dependent Expansion of Hippocampal “Place Fields”. Neuron, 31, 631-638. PMID: 11545721.