Kerr, Stephen - MCPHS University-Boston

个人简介

PhD in Medicinal Chemistry, University at Buffalo (SUNY) BS (Pharmaceutical Technology), Department of Chemical Technology, Bombay University BS (Chemistry), St. Xavier's College, Bombay University Post-doctoral Fellow, Yale University School of Medicine Honors 2014 Faculty Scholarship Showcase Award (Integration) 2014 Phi Kappa Phi – Charter Member 2012 Distinguished Trustees Award for Teaching Excellence 2011 Pharmaceutical Sciences Teacher of the Year Award 2010 Scholarly Publication Award (Basic Sciences) - MCPHS 2010 One Year Faculty Service Award, MCPHS 2007 Long Term Faculty Service Award, MCPHS 2007 Phi Lambda Sigma (National Pharmacy Leadership Society) - Faculty Inductee 2004 Short Term Faculty Service Award, MCPHS 2003 Rho Chi (Academic Honor Society in Pharmacy) - Faculty Inductee 2002 Sigma Xi (Scientific Research Society) - Inductee 1999 Scholarly Publication Award (Basic Sciences) - MCPHS 1992 -1996 Post-doctoral Research Fellowship, Yale University School of Medicine

近期论文

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Silva MA, Chuong M, Kerr S, Cabrera A. (2013) “Stability of two long acting insulin formulations after 28 days” J Pharmacy Practice and Research, 43, 37-40. Kerr, S.G. (2012) “Drug Discovery Through Enzyme Inhibition” In Foye’s Principles of Medicinal Chemistry. Eds. T. Lemke and D.W. Williams. (7th. ed . Lippincott, Williams and Wilkins, Baltimore, USA) Chen M, Howe, D, LeDuc, B, Kerr, SG and Williams, DA. (2010) "Identification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of Chloramphenicol." Drug Metab. Dispos. 38: 368 - 375. R. Sarangarajan, G. Acquaah-Mensah, K. A. Hoey, S. Kerr (2009). Transition From Primary To Metastatic Melanoma Is Associated With Differential Expression Of Genes Regulating Intracellular Levels Of Glutathione (GSH). Melanoma and Pigment Cell Research, 22 (7),PP10-3, 317, 2009. G. Acquaah-Mensah, K. A. Hoey, S. Kerr and R. Sarangarajan.(2009) "Transcriptional regulatory relationships involving Glutathione S-Transferase (GST) and oxidative stress related gene products: targets influencing melanotoxicity of substituted phenols." The Toxicologist CD - An official Journal of the Society of Toxicology, Volume 102, Number S-1, PS 935, March 2009. K. A. Hoey, S. Kerr and R. Sarangarajan (2009). "Expression/activity of Glutathione S-Transferase isoform (GST-?) is associated with increased sensitivity to 4-tertiary butylphenol (4-TBP) toxicity: implications for occupational vitiligo." The Toxicologist CD - An official Journal of the Society of Toxicology, Volume 102, Number S-1, PS 1054, March 2009. Sarangarajan, R., Friel, C and Kerr, S (2008) . "Characterization of the interaction between antioxidants and 4-TBP in the etiology of occupational vitiligo." Melanoma and Pigment Cell Research, 21 (7),PP10-3, 317, 2008. Kerr, S.G. (2007) "Drug Discovery Through Enzyme Inhibition" in Foye's Principles of Medicinal Chemistry. Eds. T. Lemke and D.W. Williams. (6th. ed . Lippincott, Williams and Wilkins, Baltimore, USA) Chen M, Howe, D, LeDuc, B, Kerr, SG and Williams, DA. (2007). "Identification and Characterization of Two Chloramphenicol Glucuronides from the in vitro Glucuronidation of Chloramphenicol in Human Liver Microsomes." Xenobiotica 37 (9): 954 -971. Kerr SG and Anderson KS. (1997) "Pre-Steady State Kinetic Characterization of Wild Type and 3'-Azido-3'-deoxythymidine (AZT) Resistant Immunodeficiency Virus Type 1 Reverse Transcriptase: Implication of RNA Directed DNA Polymerization in the Mechanism of AZT Resistance." Biochemistry 36, 14064 - 14070. Kerr SG and Anderson, KS. (1997) “RNA Dependent DNA Replication Fidelity of HIV-1 Reverse Transcriptase: Evidence of Discrimination Between DNA and RNA Substrates.” Biochemistry 36, 14056 – 14063. Kerr, S. G. and Kalman, T.I. (1994) “N4-(Dialkylamino)methylene Derivatives of 2’-deoxycytidine and Arabinosyl Cytosine: Physicochemical Studies for Potential Prodrug Applications.” J. Pharm. Sci. 83: 582 586. Kerr, S. G. and Kalman, T.I. (1992) "Highly Water Soluble Lipophilic Prodrugs of the Anti-HIV Nucleoside Analogue 2',3'-Dideoxycytidine (ddC) and it's 3'-Fluoro Derivative." J. Med. Chem. 35: 1996 - 2001.