研究领域
Supramolecular chemistry applied to problems in materials science, biology and medicine
Research Interests:
Lipids and membranes, drug delivery, drug design, Langmuir-Blodgett films
Teaching Interests:
Lipids and membranes, organic chemistry, undergraduate research en masse
近期论文
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Krause, M.; Daly, T.; Almeida, P. F.; Regen, S. L. Push–Pull Mechanism for Lipid Raft Formation, Langmuir, Article ASAP
Lin, C.; Chen, Q.; Yi, S.; Wang, M.; Regen, S. L. Polyelectrolyte Multilayers on PTMSP as Asymmetric Membranes for Gas Separations: Langmuir–Blodgett versus Self-Assembly Methods of Anchoring, Langmuir, 2014, 30 (3), pp 687–691
Janout, V.; Cline, L. L.; Feuston, B. P.; Klein, L.; O’Brien, A.; Tucker, T.; Yuan, Yu.; O’Neill-Davis, L. A.; Peiffer, R. L.; Nerukar, S. S.; Jadhav, V.; Tellers, D. M.; Regen, S. L. Molecular Umbrella Conjugate for the Ocular Delivery of siRNA, Bioconjugate Chem., 2014, 25 (2), pp 197–201
Wang, M.; Yi, S.; Janout, V.; Regen, S. L. A 7 nm Thick Polymeric Membrane With a H2/CO2 Selectivity of 200 That Reaches the Upper Bound, Chem. Mater., 2013, 25 (19), pp 3785–3787
Wang, M.; Janout, V.; Regen, S. L. Unexpected barrier properties of structurally matched and unmatched polyelectrolyte multilayers, Chem. Commun., 2013, 49, 3576-3578
Krause, M.; Turkyilmaz, S.; Regen, S. L. Surface Occupancy Plays a Major Role in Cholesterol’s Condensing Effect, Langmuir, 2013, 29 (33), pp 10303–10306
Wang, M.; Janout, V.; Regen, S. L. Gas Transport across Hyperthin Membranes, Acc. Chem. Res., 2013, 46 (12), pp 2743-2754
Daly, T. A.; Almeida, P. F.; Regen, S. L. Sorting of Lipidated Peptides in Fluid Bilayers: A Molecular-Level Investigation, J. Am. Chem. Soc., 2012, 134, 17245-17252.
Janout, V.; Daly, T. A.; Cline, L. L.; Kulp, L. J.; Regen, S. L. Stimulated Release of Cholesterol From Liposomal Membranes by a PEGylated Phospholipid, Bioconjugate Chem., 2012, 23,336-339.
Wang, M.; Janout, V.; Regen, S. L. Minimizing Defects in Polymer-based Langmuir-Blodgett Monolayers and Bilayers Via Gluing Langmuir, 2012, 28, 4614-4617.
Daly, T. A.; Wang, M.; Regen, S. L. The Origin of Cholesterol's Condensing Effect Langmuir,2011, 27, 2159-2161.
Cline, L. L.; Janout, V.; Fisher, M.; Juliano, R. L.; Regen, S. L. A Molecular Umbrella Approach to the Intracellular Delivery of siRNA, Bioconjugate Chem., 2011, 22, 2210-2216.
Turkyilmaz, S.; Almeida, P. F.; Regen, S. L. Effects of Isoflurane, Halothane, and Chloroform on the Interactions and Lateral Organization of Lipids in the Liqiod-Ordered Phase, Langmuir,2011, 27, 14380-14385.
Wang, M.; Janout, V.; Regen, S. L. Hyper-thin Organic Membranes with Exceptional H2/CO2Permeation Selectivity: Importance of Ionic Crosslinking and Self-Healing, Chem. Comm.,2011, 47, 2387-2389
Wang, M.; Janout, V.; Regen, S. L. Glued Langmuir-Blodgett Bilayers from Calix[n]arenes: Influence of Calix[n]arene Size on Ionic Cross-Linking, Film Thickness, and Permeation Selectivity, Langmuir, 2010, 26, 12988-12993.
Janout, V.; Turkyilmaz, S.; Wang, M.; Wang, Y.; Manaka, Y.; Regen, S. L. An Upside Down View of Cholesterol's Condensing Effect: Does Surface Occupancy Play a Role? Langmuir,2010, 26, 5316-5318.
Turkyilmaz, S.; Mitomo, H.; Chem, W.-H.; Regen, S. L. Phospholipid Complexation of General Anesthetics in Fluid Bilayers Langmuir, 2010, 26, 5309-5311.
Wang, Y.; Janout, V.; Regen, S. L. Creating Poly(ethylene oxide)-Based Polyelectrolytes for Thin Film Construction Using an Ionic LInker Strategy, Chem. Mater., 2010, 22, 1285-1287.
Chen, W.-H.; Janout, V.; Kondo, M,; Mosoian, A.; Goar, M.; Petrov, R. R.; Klotman, M. E.; Regen, S. L., A Fine Line Between Molecular Umbrella Transport and Ionophoric Activity,Bioconj. Chem., 2009, 20, 1711-1715.
Mitomo, H.; Chen, W.-H.; Regen, S. L., Oxysterol Induced Rearrangement of the Liquid-Ordered Phase: A Possible Link to Alzheimer's Disease?, J. Am. Chem. Soc., 2009, 131,12354-12357.
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