研究领域

Biochemistry

The molecular mechanism of estrogen-like activities of bisphenol A: Activity reinforcement of bisphenol A-bound estrogen receptors (ER) by estrogen-related receptors (ERR) keyword : bisphenol A, estrogen-related receptor, estrogen receptor, estrogen-like activities, activity reinforcement 2012.04. Specific transcription activity of halogen-containing bisphenols for estrogen receptor subtypes keyword : bisphenol, estrogen receptor, halogen bond, transfection activity 2008.04. Structural requirements of the human nuclear receptor ERRγ in its specific binding of bisphenol A keyword : bisphenol A, estrogen-related receptor, endocrine disruptor, nuclear receptor, low does effects 2006.10.

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LIU, X., MATSUSHIMA, A., SHIMOHIGASHI, M., SHIMOHIGASHI, Y.,A Characteristic Back Support Structure in the Bisphenol　A-Binding Pocket in the Human Nuclear Receptor ERRgamma,PLoS ONE,Vol.9(6): e101252. ,2014.06. Liu, X., Nishimura, H., Fujiyama, A., Matsushima, A., Shimohigashi, Y.,Constitutive α-helix-peptides required for functional dimerization of estrogen-related receptor γ (ERRγ),Peptide Science 2013,2014.03. Matsuyama, Y., Liu, X., Nishimura, H., Matsushima, A., Shimohigashi, Y.,Three-dimensional docking modeling to human nuclear receptors for exploration of bisphenol-A targeting receptors,Peptide Science 2013,2014.03. Matsuo, A., Umeno, S., Matsuyama, Y., Nakamura, M., Takeda, Y., Sumiyoshi, M., Liu, X., Matsushima, A., Shimohigashi, M., Shimohigashi, Y.,Bisphenol A-induced epigenetic mutations in circadian pacemaker neuropeptide mRNAs of hyperactive Drosophila fruit flies,Peptide Science 2013,2014.03. Umeno, S., Matsuo, A., Matsuyama, Y., Nakamura, M., Takeda, Y., Sumiyoshi, M., Liu, X., Matsushima, A., Shimohigashi, M., Shimohigashi, Y.,Influence analysis of the circadian evening pacemaker neuropeptide hugγ gene in the bisphenol A-exposed fruit fly Drosophila Brain,Peptide Science 2013,2014.03. Sugiyama, M., Matsuo, A., Saito, T., Uchimura, E., Liu, X., Matsushima, A., Shimohigashi, Y.,Expression and mutation analyses of brain neuropeptide genes of endocrine-disrupting bisphenol A-exposed hypoactive mouse,Peptide Science 2013,2014.03.