Kelson, Eric - California State University, Northridge - Department of Chemistry and Biochemistry

个人简介

B.S., University of Utah, 1988 Ph.D., California Institute of Technology, 1993 NIH Postdoctoral Research Associate, Princeton University, 1993-95

研究领域

The research underway in the Kelson laboratories is focused on the development of bifunctional ketone transfer hydrogenation catalysts with potential application for environmentally friendly and deliberately specific pharmaceutical synthesis. These catalysts are polypyridine supported ruthenium complexes designed to bind substrates and support hydrogen transfer through inter-ligand interactions. The novel design of these catalysts also render them tolerant of oxygen and independent of basic co-catalysts. Efforts are underway to extend the inter-ligand interactions beyond simple steric strategies to achieve selectivity and enantioselectivity in ketone transfer hydrogenation. As part of this work, the Kelson group has also developed single-flask methodologies for preparing novel polypyridine ligands for our designer catalysts that may also have potential as anti-tumor agents.

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

"Rad10-YFP Focus Induction in Response to UV Depends on RAD14 in Yeast," Mardiros, A., Benoun, J. M, Haughton, R., Baxter, K., Kelson, E., Fischhaber, P. Acta Histochemica (2010) (in press). "Bis(3-methoxy-2-pyridonato)aqua(2,2':6',2"-terpyridine)ruthenium(II), Hydrate, Acetonitrile (1/1/1)," Kelson, E. P., Dean, N. S., Algarin, E. Acta Crystalographica C (2007) C63, m108-m110. "FTIR Spectroscopy of Flavones in Argon and Methanol: Argon Matrices at 10K. Reexamination of the Carbonyl Stretch Frequency of 3-Hydroxyflavone," Petroski, J. M., Valente, C. D. S., Kelson, E. P., Collins, S. J. Phys. Chem. A (2002) 106, 11714-11718. "Chloro(2-pyridinecarboxaldehyde)(2,2':6',2"-terpyridine)ruthenium(II) Perchlorate, Chloro(2-pyridinecarboxylic acid) (2,2':6',2"-terpyridine)ruthenium(II) Perchlorate, Chloroform, Hydrate (1.8/0.2/1/1)," Kelson, E. P., Phengsy, P. P., Arif, A. M. Acta. Cryst. C (2001) C57, 517-519. "Synthesis and Structure of a Ruthenium(II) Complex Incorporating kN Bound 2-Pyridonato Ligands; A New Catalytic System for Transfer Hydrogenation of Ketones," Kelson, E. P., Phengsy, P. P. J. Chem. Soc., Dalton Trans. (2000), 4023-4024. "Kinetic Study of 2-Propanol and Benzyl Alcohol Oxidation by Alkane Hexacyanoferrate(III) Catalyzed by a Terpyridiyl Ruthenium Complex," Kelson, E. P., Phensy, P. P. Int. J. Chem. Kinet. (2000) 32(12), 760-770. "Electrocatalytic Oxidation by Binuclear Ruthenium Complexes Incorporating the Anionic Tripod Ligand {( 5-C5H5)Co[(CH3O)2P=O]3}-," Kelson, E.P., Henling, L.M., Schaefer, W.P., Labinger, J.A., Bercaw, J.E. Inorg. Chem. (1993) 32(13), 2863-73.