研究领域

Bioorganic Chemistry

Synthesis of ladder-shaped polyethers for elucidating mode-of-action keyword : ladder-shaped polyether, membrane protein, chemical synthesis, elucidation of mode-of-action 2009.04～2011.03.

近期论文

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Ebine, Makoto; Kanemoto, Mitsunori; Manabe, Yoshiyuki; Konno, Yosuke; Sakai, Ken; Matsumori, Nobuaki; Murata, Michio; Oishi, Tohru ,Synthesis and Structure Revision of the C43-​C67 Part of Amphidinol 3,Organic Letters ,Vol.15,No.11,pp.2846-2849,2013.05. Matsumori, Nobuaki; Hiradate, Yuki; Shibata, Hajime; Oishi, Tohru; Shimma, Shuichi; Toyoda, Michisato; Hayashi, Fumiaki; Yoshida, Manabu; Murata, Michio; Morisawa, Masaaki ,A Novel Sperm-​Activating and Attracting Factor from the Ascidian Ascidia sydneiensis,Organic Letters ,Vol.15,No.2,pp.294-297,2013.01. Nobuaki Matsumori, Norio Tanada, Kohei Nozu, Hiroki Okazaki, Tohru Oishi, Michio Murata ,Design and Synthesis of Sphingomyelin-Cholesterol Conjugates and Their Formation of Ordered Membranes,Chemistry--A European Journal,Vol.17,No.31,pp.8568-8575,2011.07. Keisuke Maruyoshi, Toshiyuki Yamaguchi, Tetsuo Demura, Nobuaki Matsumori, Tohru Oishi, Michio Murata ,Conformations of spermine in adenosine triphosphate complex: The structural basis for weak bimolecular interactions of major cellular electrolytes,Chemistry--A European Journal,Vol.17,No.17,pp.4788-4795,2011.03. Respati T. Swasono, Mitsunori Kanemoto, Nobuaki Matsumori, Tohru Oishi, Michio Murata ,Structural reevaluations of amphidinol 3, a potent antifungal compound from dinoflagellate, Heterocycles ,Vol.82,No.2,pp.1359-1369,2011.01. Yusuke Kasai, Nobuaki Matsumori, Hiroyuki Ueno, Kenichi Nonomura, Shinya Yano, Murata Michio, Tohru Oishi ,Synthesis of 6-F-ergosterol and its influence on membrane-permeabilization of amphotericin B and amphidinol 3,Organic & Biomolecular Chemistry ,Vol.9,No.5,pp.1437-1442,2011.01. Satoru Ujihara, Tohru Oishi, Ryota Mouri, Rie Tamate, Keiichi Konoki, Nobuaki Matsumori, Michio Murata, Yasukatsu Oshima, Naoyuki Sugiyama, Masaru Tomita, Yasushi Ishihama,Detection of Rap1A as a yessotoxin binding protein from blood cell membranes.,Bioorg. Med. Chem. Lett.,Vol.20,pp.6443-6446,2010.01. Respati Swasono, Ryota Mouri, Nagy Morsy, Nobuaki Matsumori, Tohru Oishi, Michio Murata,Sterol Effect on Interaction between Amphidinol 3 and Liposomal Membrane as Evidenced by Surface Plasmon Resonance.,Bioorg. Med. Chem. Lett.,Vol.20,pp.2215-2218,2010.01. Tohru Oishi, Kouichiro Ootou, Hajime Shibata, Michio Murata,Second-Generation Synthesis of Endogenous Sperm-Activating and Attracting Factor (SAAF) Isolated from the Ascidian Ciona intestinalis.,Tetrahedron Lett.,Vol.51,pp.2600-2602,2010.01. Tohru Oishi, Tomoyoshi Imaizumi, Michio Murata,Reductive Etherification under Microfluidic Conditions: Application to Practical Synthesis of the FGHIJ-Ring System of Yessotoxin.,Chem. Lett.,Vol.39,No.2,pp.108-109,2010.01. Naohiro Matsushita, Yukiko Matsuo, Hiroshi Tsuchikawa, Nobuaki Matsumori, Michio Murata, Tohru Oishi,Synthesis of 25-13C-Amphotericin B Methyl Ester: A Molecular Probe for Solid-state NMR Measurements.,Chem. Lett.,Vol.38,pp.114-115,2009.01. Keisuke Maruyoshi, Kaori Nonaka, Takeshi Sagane, Tetsuo Demura, Toshiyuki Yamaguchi, Nobuaki Matsumori, Tohru Oishi, Michio Murata,Conformational Change of Spermidine upon Interaction with Adenosine Triphosphate in Aqueous Solution.,Chem. Eur. J.,Vol.15,pp.1618-1626,2009.01. Keiichi Konoki, Masaki Hashimoto, Kaori Honda, Kazuo Tachibana, Rie Tamate, Futoshi Hasegawa, Tohru Oishi, Michio Murata,Maitotoxin-Photoactive Probe Binds to Membrane Proteins in Blood Cells.,Heterocycles,Vol.79,pp.1007-1017,2009.01. Ryota Mouri, Tohru Oishi, Kohei Torikai, Satoru Ujihara, Nobuaki Matsumori, Michio Murata, Yasukatsu Oshima,Surface Plasmon Resonance-Based Detection of Ladder-Shaped Polyethers by Inhibition Detection Method.,Bioorg. Med. Chem. Lett.,Vol.19,pp.2824-2828,2009.01. Michio Murata, Yusuke Kasai, Yuichi Umegawa, Naohiro Matsushita, Hiroshi Tsuchikawa, Nobuaki Matsumori, Tohru Oishi,Ion Channel Complex of Antibiotics as Viewed by NMR.,Pure Appl. Chem.,Vol.81,pp.1123–1129,2009.01. Nobuaki Matsumori, Kazuaki Tahara, Hiroko Yamamoto, Atsushi Morooka, Mototsugu Doi, Tohru Oishi, Michio Murata,Direct Interaction between Amphotericin B and Ergosterol in Lipid Bilayers As Revealed by 2H NMR Spectroscopy.,J. Am. Chem. Soc.,Vol.131,pp.11855–11860,2009.01. Mitsunori Kanemoto, Michio Murata, Tohru Oishi,Stereoselective Synthesis of the C31-C40/C43-C52 Unit of Amphidinol 3,J. Org. Chem.,Vol.74,pp.8810–8813,2009.01. Nobuaki Matsumori, Yusuke Kasai, Tohru Oishi, Michio Murata, Kaoru Nomura,Orientation of Fluorinated Cholesterol in Lipid Bilayers Analyzed by 19F Tensor Calculation and Solid-State NMR.,J. Am. Chem. Soc.,Vol.130,pp.4757-4766,2008.01. Nagy Morsy, Toshihiro Houdai, Keiichi Konoki, Nobuaki Matsumori, Tohru Oishi, Michio Murata,Effects of Lipid Constituents on Membrane-Permeabilizing Activity of Amphidinols.,Bioorg. Med. Chem.,Vol.16,pp.3084-3090,2008.01. Yusuke Kasai, Nobuaki Matsumori, Yuichi Umegawa, Shigeru Matsuoka, Hiroyuki Ueno, Hiroki Ikeuchi, Tohru Oishi, Michio Murata,Self-Assembled Amphotericin B is Probably Surrounded by Ergosterol: Bimolecular Interactions as Evidenced by Solid-State NMR and CD Spectra.,Chem. Eur. J.,Vol.14,pp.1178-1185,2008.01