研究领域

Biochemistry, Cell Biology, Genetics

Biosynthetic regulation and intracellular transport of phospholipids keyword : Biological Membranes, Phospholipids, Biosynthetic Regulation, Intracellular Transport 2000.01.

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Motohiro Tani, Osamu Kuge,Involvement of Sac1 phosphoinositide phosphatase in the metabolism of phosphatidylserine in the yeast Saccharomyces cerevisiae.,Yeast,2014.02. Yasushi Tamura, Yoshihiro Harada, Shuh-ichi Nishikawa, Koji Yamano, Megumi Kamiya, Takuya Shiota, Takuya Kuroda, Osamu Kuge, Hiromi Sesaki, Kenichiro Imai, Kentaro Tomii, Toshiya Endo,Tam41 Is a CDP-Diacylglycerol Synthase Required for Cardiolipin Biosynthesis in Mitochondria,CELL METABOLISM,Vol.17,No.5,pp.709-718,2013.05. Tani Motohiro, Kuge Osamu,Involvement of complex sphingolipids and phosphatidylserine in endosomal trafficking in yeast Saccharomyces cerevisiae,MOLECULAR MICROBIOLOGY,Vol.86,No.5,pp.1262-1280,2012.12. Lee Shoken, Uchida Yasunori, Emoto Kazuo, Umeda, Masato, Kuge Osamu, Taguchi Tomohiko, Arai Hiroyuki,Impaired retrograde membrane traffic through endosomes in a mutant CHO cell defective in phosphatidylserine synthesis,GENES TO CELLS,Vol.17,No.8,pp.728-736,2012.08. Tani M, Kuge O.,Hydroxylation state of fatty acid and long-chain base moieties of sphingolipid determine the sensitivity to growth inhibition due to AUR1 repression in Saccharomyces cerevisiae.,Biochem Biophys Res Commun.,Vol.417,No.2,pp.673-678,2012.01. Kuroda T, Tani M, Moriguchi A, Tokunaga S, Higuchi T, Kitada S, Kuge O.,FMP30 is required for the maintenance of a normal cardiolipin level and mitochondrial morphology in the absence of mitochondrial phosphatidylethanolamine synthesis.,Mol Microbiol.,Vol.80,No.1,pp.248-265,2011.04. Tani M, Kuge O.,Requirement of a specific group of sphingolipid-metabolizing enzyme for growth of yeast Saccharomyces cerevisiae under impaired metabolism of glycerophospholipids.,Mol Microbiol. ,Vol.78,No.2,pp.395-413,2010.09. Tani M, Kuge O.,Defect of synthesis of very long-chain fatty acids confers resistance to growth inhibition by inositol phosphorylceramide synthase repression in yeast Saccharomyces cerevisiae.,J Biochem.,Vol.148,No.5,pp.565-571,2010.11. Gilquin, B., Taillebourg, E., Cherradi, N., Hubstenberger, A., Gay, O., Merle, N., Assard, N., Fauvarque, M.-O., Tomohiro, S., Kuge, O., and Baudier, J.,The AAA+ ATPase ATAD3A controls mitochondrial dynamics at the interface of the inner and outer membranes.,Mol Cell Biol.,Vol.30,No.8,pp.1984-1996,2010.04. Kuroda, T., Tani, M., Moriguchi, A., Tokunaga, S., Higuchi, T., Kitada, S., and Kuge, O.,Identification of a novel gene involved in cardiolipin metabolism and mitochondrial morphology in the yeast Saccharomyces cerevisiae,Chemistry and Physics of Lipids,Vol.160, Supplement,pp.S29,2009.08. Motohiro Tani, Osamu Kuge,Sphingomyelin synthase 2 is palmitoylated at the COOH-terminal tail, which is involved in its localization in plasma membrane,Biochem. Biophys. Res. Commun.,Vol.381,No.3,pp.328-332,2009.04. Shiho Tomohiro, Ayako Kawaguti, Yukiyo Kawabe, Sakae Kitada, Osamu Kuge,Purification and characterization of human phosphatidylserine synthases 1 and 2,Biochem. J.,2009.03. Kazuhisa Yoshino, Hiroshi Munakata, Osamu Kuge, Akio Ito, and Tadashi Ogishima,Haeme-regulated degradation of δ-aminolevulinate synthase 1 in rat liver mitochondria,J. Biochem.,142, 453-458,2007.11. Kitada S, Abe Y, Shimada H, Kusaka Y, Matsuo Y, Katayama H, Okumura S, Akao T, Mizuki E, Kuge O, Sasaguri Y, Ohba M, Ito A,Cytocydal actions of parasporin-2, an anti-tumor crystal toxin from Bacillus thuringiensis,J Biol Chem.,281 (36) 26350-26360,2006.09. Kyoko Saito, Masahiro Nishijima, Osamu Kuge,Phosphatidylserine is involved in gene expression from Sindbis virus subgenomic promoter,Biochem Biophys Res Commun.,2006.06. Qizong Lao, Toshihiko Fukamachi, Hiromi Saito, Osamu Kuge, Masahiro Nishijima, Hiroshi Kobayashi,Requirement of an IkappaB-COOH terminal region protein for acidic-adaptation in CHO cells,Journal of Cellular Physiology,207, 238-243,2006.04. Qizong Lao, Osamu Kuge, Toshihiko Fukamachi, Kakegawa Tomohiro, Hiromi Saito, Masahiro Nishijima, and Hiroshi Kobayashi,An IκB-β COOH terminal region protein is essential for the proliferation of CHO cells under acidic stress,Journal of Cellular Physiology,Vol.203,No.1,Vol. 203, pp186-192,2004.01. Tomoko Ohsawa, Masahiro Nishijimam and Osamu Kuge,Functional analysis of Cinese hamster phosphatidylserine synthase 1 trough systematic alanine mutagenesis,Biochem. J.,Vol.381,Vol. 381, pp853-859,2004.01. Osamu Kuge, Kazuhide Hasegawa, Tomoko Ohsawa, Kyoko Saito, and Masahiro Nishijima,Purification and characterization of Chinese hamster phosphatidylserine synthase 2,J. Biol. Chem.,Vol.278,No.43,Vol. 278, No. 43, pp. 42692-42698,2003.10. Osamu Kuge, Yoshio Yamakawa, and Masahiro Nishijima,Enhancement of transport-dependent decarboxylation of phosphatidylserine by S100B protein in permeabilized Chinese hamster ovary cells,J.Biol. Chem.,Vol. 276, No. 26, pp.23700-23706,2001.06.