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个人简介

教育经历 [1] 2009.9-2014.6 西南交通大学 材料学 博士研究生毕业 工学博士学位 [2] 2005.9-2008.7 西南交通大学 材料物理与化学 硕士研究生毕业 工学硕士学位 [3] 2001.9-2005.7 南昌航空工业学院 高分子材料与工程 大学本科毕业 工学学士学位 工作经历 [1] 2019.12-至今 西南交通大学 研究员 [2] 2015.4-2019.12 西南交通大学 副教授 杨志禄,工学博士,研究员,博士生导师,西南交通大学“扬华学者”,四川省杰出青年基金获得者。中国生物材料学会科学技术奖一等奖获得者(排名:2/7)。现任KeAi旗下国际期刊Smart Materials in Medicine主编、中国科协旗舰刊Research编委、Bioactive Materials(IF: 14.593,生物材料领域排名第一)编委及Engineered Regeneration编委。目前,担任中国生物材料学会康复器械与生物材料分会常务委员、中国病理生理学会专业委员会青年委员、中国生物材料学会医用金属材料分会委员,中国生物材料学会血液净化材料分会委员,中国生物材料学会生物材料表界面工程分会委员,中国腐蚀与防护学会医用金属材料腐蚀控制分会委员。

研究领域

[1]血管动脉粥样硬化病理发病机制 [2]病理免疫 [3]纳米理疗气体与靶向药物 [4]药物球囊 [5]心血管植入/介入器械 [6]组织再生工程 [7]生物材料表面与界面

近期论文

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Jie Sun, Yingkang Huang, Huan Zhao, Junjie Niu, Xuwei Ling, Can Zhu, Lin Wang, Huilin Yang, Zhilu Yang*, Guoqing Pan*, Qin Shi*. Bio-clickable mussel-inspired peptides improve titanium-based material osseointegration synergistically with immunopolarization-regulation. Bioactive Materials. 2022;9:1-14. Ying Wang, Ranjith Kumar Kankala, Caiwen Ou, Aizheng Chen*, Zhilu Yang*. Advances in hydrogel-based vascularized tissues for tissue repair and drug screening. Bioactive Materials. 2022;9:198-220. Yin Chen#, Peng Gao#, Lu Huang, Xing Tan, Ningling Zhou, Tong Yang, Hua Qiu, Xin Dai, Sean Michael, Qiufen Tu, Nan Huang, Zhihong Guo, Jianhua Zhou*, Zhilu Yang*, Hongkai Wu*. A tough nitric oxide-eluting hydrogel coating suppresses neointimal hyperplasia on vascular stent. Nature Communications. 2021;12:7079. Qing Ma#, Xiuying Shi#, Xing Tan, Rui Wang, Kaiqin Xiong, Manfred F. Maitz, Yuanyuan Cui, Zhangmei Hu, Qiufen Tu*, Nan Huang, Li Shen*, Zhilu Yang*. Durable endothelium-mimicking coating for surface bioengineering cardiovascular stents. Bioactive Materials. 2021;12:4786-4800. Han Yu#, Hua Qiu#, Wenmei Ma, Manfred F. Maitz, Qiufen Tu, Kaiqin Xiong, Jiang Chen*, Nan Huang*, Zhilu Yang*. Endothelium-Mimicking Surface Combats Thrombosis and Biofouling via Synergistic Long- and Short-Distance Defense Strategy. Small. 2021;2100729. Hua Qiu, Qiufen Tu, Peng Gao, Xiangyang Li, Manfred F. Maitz, Kaiqin Xiong*, Nan Huang, Zhilu Yang*. Phenolic-amine chemistry mediated synergistic modification with polyphenols and thrombin inhibitor for combating the thrombosis and inflammation of cardiovascular stents. Biomaterials. 2021; 269:120626. Han Yu, Shaoxing Yu, Hua Qiu, Peng Gao, Yingzhong Chen, Xin Zhao, Qiufen Tu, Minggang Zhou*, Lin Cai, Nan Huang, Kaiqin Xiong*, Zhilu Yang*. Nitric oxide-generating compound and bio-clickable peptide mimic for synergistically tailoring surface anti-thrombogenic and anti-microbial dual-functions. Bioactive Materials. 2021;6:1618–1627. Nan Lyu, Zeyu Du, Hua Qiu, Peng Gao, Qin Yao, Kaiqin Xiong, Qiufen Tu, Xiangyang Li, Binghai Chen, Guoqing Pan*, Nan Huang*, Zhilu Yang*. Mimicking the Nitric Oxide-Releasing and Glycocalyx Functions of Endothelium on Vascular Stent Surfaces. Advanced Science. 2020;7:202002330. Zhilu Yang#, Xin Zhao#, Rui Hao, Qiufen Tu, Xiaohua Tian, Yu Xiao, Kaiqin Xiong, Miao Wang, Yonghai Feng, Nan Huang*, Guoqing Pan*. Bio-clickable and Mussel Adhesive Peptide Mimics for Engineering Vascular Stent Surfaces. PNAS. 2020;117:16127-16137. Yu Xiao, Wenxuan Wang, Xiaohua Tian, Xing Tan, Tong Yang, Peng Gao, Kaiqing Xiong, Qiufen Tu, Miao Wang, Manfred F. Maitz, Nan Huang, Guoqing Pan*, Zhilu Yang*. A Versatile Surface Bioengineering Strategy Based on Mussel-Inspired and Bioclickable Peptide Mimic. Research. 2020;2020:7236946. Ying Yang, Peng Gao, Juan Wang, Qiufen Tu, Long Bai, Kaiqin Xiong, Hua Qiu, Xin Zhao, Manfred F. Maitz, Huaiyu Wang, Xiangyang Li, Qiang Zhao, Yin Xiao, Nan Huang*, Zhilu Yang*. Endothelium-Mimicking Multifunctional Coating Modified Cardiovascular Stents via a Stepwise Metal-Catechol-(Amine) Surface Engineering Strategy. Research. 2020;2020:9203906. Peng Gao, Hua Qiu, Kaiqin Xiong, Xiangyang Li, Qiufen Tu, Huaiyu Wang, Nan Lyu, Xiao Chen, Nan Huang*, Zhilu Yang*. Metal-Catechol-(Amine) Networks for Surface Synergistic Catalytic Modification: Therapeutic Gas Generation and Biomolecule Grafting. Biomaterials. 2020;248:119981. Tong Yang, Zeyu Du, Hua Qiu, Peng Gao, Xin Zhao, Huaiyu Wang, Qiufen Tu, Kaiqin Xiong, Nan Huang, Zhilu Yang*. From surface to bulk modification: Plasma polymerization of amine-bearing coating by synergic strategy of biomolecule grafting and nitric oxide loading. Bioactive Materials. 2020;5:17-25. Xiangyang Li#, Jingxia Liu#, Tong Yang, Hua Qiu, Lei Lu, Qiufen Tu, Kaiqing Xiong, Nan Huang*, Zhilu Yang*. Mussel-inspired “built-up” surface chemistry for combining nitric oxide catalytic and vascular cell selective properties. Biomaterials. 2020;241:119904. Hua Qiu#, Pengkai Qi#, Xing Tan, Yu Xiao, Jingxia Liu, Lei Lu, Peng Gao, Ying Yang, Nan Huang*, Zhilu Yang*. Biomimetic Engineering Endothelium-like Coating on Cardiovascular Stent through Heparin and Nitric Oxide-Generating Compound Synergic Modification Strategy. Biomaterials. 2019;207:10-22. Feng Zhang#, Qiang Zhang#, Xiangyang Li, Nan Huang, Xin Zhao*, Zhilu Yang*. Mussel-inspired dopamine-CuII coatings for sustained in situ generation of nitric oxide for prevention of stent thrombosis and restenosis. Biomaterials. 2019;194:117-129. Zhilu Yang*, Ying Yang, Kaiqin Xiong, Jin Wang, Haeshin Lee*, Nan Huang*, Metal-Phenolic Surfaces for Generating Therapeutic Nitric Oxide Gas. Chemistry of Materials. 2018;30:5220-5226. Zhilu Yang*, Ying Yang, Li Zhang, Kaiqin Xiong, Xiangyang Li, Feng Zhang, Jin Wang, Xin Zhao*, Nan Huang*, Mussel-inspired Catalytic Selenocystamine-Dopamine Coatings for Long-Term Generation of Therapeutic Gas on Cardiovascular Stents. Biomaterials. 2018;178:1-10. Zhilu Yang*, Ying Yang, Kaiqin Xiong, Xiangyang Li, Pengkai Qi, Qiufen Tu, Fengjuan Jing, Yajun Weng, Jin Wang*, Nan Huang*. Nitric oxide producing coating mimicking endothelium function for multifunctional vascular stents. Biomaterials. 2015;63:80-92.

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