个人简介

B.S. Chemistry, 1990, University of Hamburg, Germany Visiting Scholar, 1991, University of Reading, Reading, UK Diploma Chemistry, 1993, University of Hamburg, Germany Visiting Scholar, 1994 and 1995, University of Aix-Marseille III, Marseille, France Ph.D. Chemistry, 1995, University of Hamburg, Germany Postdoctoral Fellow, 1996-1997, University of Illinois Scientist, 1998-2000, SmithKine Beecham Pharmaceuticals, Philadelphia.

研究领域

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Stereochemistry; Stereodynamic chemistry of chiral compounds; Asymmetric catalysis; Enantioselective sensing; Palladium-catalyzed cross-coupling reactions; High-throughput screening; Solid state chemistry; Development of new antimalarial drugs.

Students involved in research activities will gain expertise in many areas of organic, bioorganic and analytical chemistry, chiral recognition studies, investigation of the stereodynamics of chiral compounds using variable-temperature NMR and dynamic chromatography, high-throughput screening of chiral catalysts, transition metal-catalyzed cross-coupling reactions, drug discovery and development, and chiral chromatography. Our routine bench work includes the handling of reactive compounds under inert atmosphere and cryogenic conditions as well as purification of reaction products by flash chromatography and other techniques. In addition, we use various techniques such as NMR, IR, CD, fluorescence spectroscopy, a microwave for synthesis, GC, LC, GC-MS, LC-MS, elemental analysis, X-ray crystallography, and enantioselective chromatography (GC, HPLC, or SFC) and electrophoresis to characterize and explore the properties of rationally designed organic compounds.