Narayanaswami, Vasanthy - California State University, Long Beach

个人简介

PhD, Indian Institute of Technology (Madras), Chennai, India Post doctoral fellow, Alexander von Humboldt fellow, University of Dusseldorf, Germany Post doctoral fellow, University of Alberta, Edmonton, Canada Associate Scientist, Children.s Hospital Oakland Research Institute, Oakland, CA

研究领域

Apolipoprotein E and Cholesterol Transport in Aging and Disease Disease

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Kim, S. H., Cruz, S., Adhikari, B. B., Schramm, M. P., Vinson, J. A. & Narayanaswami, V. (2015) Targeted Intracellular Delivery of Resveratrol to Glioblastoma Cells using Apolipoprotein E-Containing Reconstituted HDL as a Nanovehicle. PLoS ONE 10(8): e0135130. doi:10.1371/journal.pone.0135130 Kim, S. H., Kothari, S., Patel, A. B., Bielicki, J. K. & Narayanaswami, V. (2014) A Pyrene Based Fluorescence Approach to Study Conformation of Apolipoprotein E3 in Macrophage-generated Nascent High Density Lipoprotein. Biochem. Biophys. Res. Commun. doi: 10.1016/j.bbrc.2014.05.071. [Epub ahead of print] Tran, T. N., Kosaraju, M. G., Tamamizu-Kato, S., Akintunde, O., Zheng, Y., Bielicki, J. K., Pinkerton, K, Uchida, K., Lee, Y. Y. & Narayanaswami, V. (2014) Acrolein Modification Impairs Key Functional Features of Rat Apolipoprotein E: Identification of Modified Sites by Mass Spectrometry. Biochemistry 53, 361-375 (PMCID # PMC3937454). Zheng, Y., Patel, A. B., Narayanaswami, V. & Bielicki, J. K. (2013) Retention of .-helical structure by HDL mimetic peptide ATI-5261 upon extensive dilution represents an important determinant for stimulating ABCA1 cholesterol efflux with high efficiency. Biochem. Biophys. Res. Commun. 441, 71-76 (PMID # 24129191- PubMed In Process). Tran, T. N., Kim, S. H., Gallo, C., Amaya, M., Kyees, J. and Narayanaswami, V. (2013) Biochemical and Biophysical Characterization of Recombinant Rat Apolipoprotein E: Similarities to Human Apolipoprotein E3. Arch. Biochem. Biophys. 259, 18-25 (PMCID: PMC3543869) Zheng, Y., Kim, S. H., Patel, A. B., Narayanaswami, V, Iavarone, A. T., Hura, G. L. & Bielicki, J. K. (2012) The positional specificity of EXXK motifs within an amphipathic .-helix dictates preferential lysine modification by acrolein: Implications for the design of high-density lipoprotein mimetic peptides. Biochemistry DOI 10.1021/bi300626g Bains, G. K., Kim, S. H., Sorin, E. J. and Narayanaswami, V. (2012) Extent of pyrene excimer fluorescence emission is a reflector of distance and flexibility: Analysis of the segment linking the LDL Receptor-binding and tetramerization domains of apolipoprotein E3. Biochemistry DOI: 10.1021/bi3005285 Bains, G., Patel, A. B. and Narayanaswami, V. (2011) Pyrene: A probe to study protein conformation and conformational changes. Molecules 16, 7909-7935 Zheng, Y.,* Patel A. B.*, Narayanaswami, V., Hura, G. L., Hang, B., and Bielicki, J. K. (2011) HDL mimetic peptide ATI-5261 forms an oligomeric assembly in solution that dissociates to monomers upon dilution. Biochemistry 50, 4068-4076 (*equal contribution) Khumsupan, P., Ramirez, R., Khumsupan, D. and Narayanaswami, V. (2011) Apolipoprotein E LDL receptor-binding domain-containing high-density lipoprotein: A nanovehicle to transport curcumin, an antioxidant and anti-amyloid bioflavonoid. Biochim Biophys Acta 1808, 352-359. Hauser, P. S., Narayanaswami, V. and Ryan, R. O. (2011) Apolipoprotein E: From lipid transport to neurobiology. Prog. Lipid Res. 50, 62-74. Narayanaswami, V., Kiss, R. S. and Weers, P. M. (2010) The helix bundle: a reversible lipid binding motif. Comparative Biochem. Physiol. A Mol. Integr. Physiol. 155, 123-133. Bielicki, J. K., Zhang, H., Cortez, Y., Narayanaswami, V., Patel, A. B., Johansson, J. and Azhar, S. (2010) A new HDL mimetic peptide that stimulates cellular cholesterol efflux with high efficiency greatly reduces atherosclerosis in mice. J. Lipid Res. 51, 1496-1503. Patel, A. B., Khumsupan, P. and Narayanaswami, V. (2010) Pyrene Fluorescence Analysis Offers New Insights into the Conformation of the Lipoprotein-Binding Domain of Human Apolipoprotein E. Biochemistry 49, 1766-1775. Crutcher, K. A., Lilley, H. N., Anthony, S. R., Zhou, W. and Narayanaswami, V. (2010) Full-length apolipoprotein E protects against the neurotoxicity of an apoE-related peptide. Brain Research 1306, 106-115. Cerf, E., Sarroukh, R., Tamamizu-Kato, S., Derclaye, S., Dufrêne, Y., Narayanaswami, V., Goormaghtigh, E., Ruysschaert, J.-M. and Raussens, V. (2009) Anti-parallel beta-sheet - A signature structure of the oligomeric amyloid-beta peptide. Biochemical J. 421, 415-423.