Linder, Maria - California State University, Fullerton - Department of Chemistry & Biochemistry

个人简介

Postdoctoral M.I.T. Cambridge, MA Postdoctoral Harvard Medical School, Boston, MA Ph.D. Harvard University, Cambridge, MA B.Sc. Vassar College, Poughkeepsie, NY

研究领域

An expert on mammalian copper and iron metabolism, Dr. Linder is currently focusing her research on mechanisms of copper transport in the period before and after birth, and on the intestinal absorption and storage of iron, using a broad variety of approaches, from cell culture models, transgenic mice and tracer radioisotopes, to isolation, sequencing and characterization of proteins, as well as si/shRNA manipulation of mRNA/protein expression

近期论文

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Linder, M.C. (2010) Nutritional biochemistry of copper, with emphasis on the perinatal period. In: Biochemical Aspects of Human Nutrition (L. Avigliano and L. Rossi, eds.), ISBN 978-81-7895-478-3. Transworld Research Network, Trivandrum, Kerala, India, pp.143-179, in press. Moriya, M., Ho, Y-H., Grana, A., Nguyen, L., Alvarez, A., Jamil,, R., Ackland, M.L., Michalczyk, A., Hamer, P., Ramos,, D. Kim, S., Mercer, J.F.B., and Linder, M.C. (2008) Copper is taken up efficiently from albumin and alpha-2-macroglobulin by cultured human cells by more than one mechanism. Am. J. Physiol. (Cell Physiology) 295: 708-721. Liu, N.M., Lo, L.S.L., Askary, S.H., Jones, L.T., Nguyen, T.T.M., Kidane, T.Z., Goforth, J., Vivas, E., Tsai, M.T., Westbrook, T. and Linder, M.C. (2007) Transcuprein is a macroglobulin regulated by copper availability. J. Nutritional Biochem. 18: 597-608. Kidane,, T.Z., Sauble, E. and Linder, M.C. (2006) In three cell types, release of iron from ferritin requires lysosomal activity. Am. J. Physiol. (Cell Biol.) 291: C445-C455. Donley, S.A., Ilagan, B.J., Rim, H. and Linder, M.C. (2002) Copper transport to mammary gland and milk during lactation in rats. Am. J. Physiol. (Endoc. Metab.), 283, E667-E675.