个人简介
发酵工程工学博士,教授,博士生导师,天津市特聘教授。国家技术发明奖二等奖第一完成人,酶高效表达国家工程实验室副主任。教育部新世纪优秀人才,天津市劳动模范,天津市有突出贡献专家,全国先进科技工作者。南非德班理工大学兼职研究生导师,博、硕士学位论文国际评审专家。
研究领域
1. 工业微生物菌种选育;
2. 工业酶制剂的分子改造、高效表达与高效制备;
3. 工业微生物资源与开发利用。
近期论文
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1. Chen XZ,Zhou Li, Tian KM, Kumar A, Singh S, Prior BA, Wang Z-X* (2013). Metabolic engineering of Escherichia coli: A sustainable industrial platform for bio-based chemical production. Biotechnology Advances, 31: 1200-1223. (IF 9.848)
2. Wang Z-X, Zhuge J, Fang HY, and Prior BA (2001). Glycerol production by microbial fermentation: A review. Biotechnology Advances, 19: 201-223. (IF 9.848)
3. Chen XZ, Tian KM, Niu DD, Shen W, Algasan G, Singh S and Wang Z-X* (2014). Efficient bioconversion of crude glycerol from biodiesel to optically pure D-lactate by metabolically engineered Escherichia coli. Green Chemistry, 16(1): 342-350. (IF 8.506)
4. Zhou L, Niu DD, Tian KM, Chen XZ, Prior BA, Shen W, Shi GY, Singh S, Wang Z-X* (2012). Genetically switched D-lactate production in Escherichia coli. Metabolic Engineering, 14(5): 560-568. (IF 8.201)
5. Tian KM, Niu DD*, Liu XG, Prior BA, Zhou L, Lu FP, Singh S, Wang Z-X* (2016). Limitation of thiamine pyrophosphate supply to growing Escherichia coli switches metabolism to efficient D-lactate formation. Biotechnology Bioengineering, 113(1): 181-188. (IF 4.243)
6. Niu DD, Zuo ZR, Shi GY, Wang Z-X*(2009). High yield recombinant thermostable α-amylaseproduction using an improved Bacillus licheniformissystem. Microbial Cell Factories, 8:1-7. (IF 4.221)
7. Chen XZ, Xia Y, Shen W, Fan Y, Govender A, Wang Z-X* (2014). Engineering glycolysis branch pathways of Escherichia coli to improve heterologous protein expression. Process Biochemistry, 49(12):2063-2070. (IF 2.516)
8. Zhou L, Shen W, Niu DD, Tian KM, Prior BA,Shi GY, Singh S, Wang Z-X* (2012). Fine tuning the transcription of ldhA for D-lactate production. Journal of Industrial Microbiology and Biotechnology, 39(1):1209-1217. (IF 2.416)
9. Niu DD and Wang Z-X* (2007). Development of a pair of bifunctional expression vectors for Escherichia coli and Bacillus licheniformis.Journal of Microbiology and Biotechnology, 34:357-362. (IF 2.416)
10. 田康明,周丽,陈献忠,沈微,石贵阳,Suren Singh,路福平,王正祥*.利用温度调节实现新型重组菌高效转化甘油为D-乳酸[J].生物工程学报,2013,29(1):111-114
11. 田康明,石贵阳,路福平,Suren Singh,王正祥*.代谢工程大肠杆菌利用甘油高效合成L-乳酸[J].生物工程学报,2013,29(9):1268-1277
12. 周丽,田康明,左志锐,陈献忠,石贵阳,Suren Singh,王正祥*.大肠杆菌琥珀酸和乙酸合成途径的删除及其重组菌株的D-乳酸发酵[J].生物工程学报,2011,27(1):31-40