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个人简介

B.Sc. (Hons) University of Manitoba (1984) Ph.D. University of Manitoba (1988)

研究领域

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Receptor tyrosine kinase (RTK) overexpression is frequently observed in many human cancers and drives cell division and cell survival. One major pathway activated by these receptors is the phosphatidylinositol 3-kinase (PI3K)/Akt pathway. PI3K activity consists of a p110 catalytic protein that phosphorylates lipids that in turn activate Akt signaling. The p110 protein is stabilized and regulated by another protein, p85.

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