Chen, Daniel - University of Saskatchewan - Department of Biomedical Engineering

个人简介

Dr. Daniel Chen is a Professor with the Department of Mechanical Engineering and the Division of Biomedical Engineering. He is also the leader of Tissue Engineering Research Group that consists of a number of researchers spanning both engineering and life sciences, with a long-term research goal of developing advanced technologies for the production of various scaffold-guided tissue or organ substitutes. He is the recipient of the New Research Award 2012 of the University of Saskatchewan, recognizing his significant contributions to knowledge through research. Dr. Chen received his Ph.D. degree in mechanical engineering from the University of Saskatchewan (UofS) in 2002. He was then working on his Post-Doctorate with Queen's University, Canada. In 2003 he was appointed as an Assistant Professor with the Department of Mechanical Engineering, UofS, where he was promoted to an Associate Professor and a full Professor in 2007 and 2010, respectively. Dr. Chen's research interests include Tissue Engineering, Scaffold Bio-fabrication, Mechatronics, and Nano-Positioning. His research has been supporting by the Natural Sciences and Engineering Research Council (NSERC) of Canada, the Canadian Institutes of Health Research (CIHR), the Canada Foundation for Innovation (CFI), the Saskatchewan Health Research Foundation (SHRF), and the National Natural Science Foundation of China (NSFC). He teaches undergraduate and graduate courses in the areas of control systems, mechatronics, and tissue engineering.

研究领域

Bio-Engineering of Scaffolds for the Surgical Repair of Spinal Cord Injury Bio-Manufacturing of Tissue Engineering Scaffolds Design, Modeling, and Control of Piezoelectric Actuators for Nanopositioning Fabrication of Living-Cell Scaffolds for Spinal Cord Injury Repair On-Line Monitoring of Drill Wear to Inform Tool Replacement Tissue Engineering Group - Phase II Bio-Engineering of Scaffolds for the Surgical Repair of Spinal Cord Injury Bio-Manufacturing of Tissue Engineering Scaffolds Design, Modeling, and Control of Piezoelectric Actuators for Nanopositioning Tissue Engineering Group - Phase II

近期论文

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Zheng, H.X., Tian, W.M., Yan, H.J., Jiang, H.D., Liu, S.S., Yu, L., Han, F., Wei, L.J., Chen, D. and Li, Y. (2012). Expression of Estrogen Receptor á in Human Breast Cancer Cells Regulates Mitochondrial Oxidative Stress under Simulated Microgravity, Advances in Space Research, 49(10), 1432-1440. Cao, Y., Cheng, L., Peng, J.Y. and Chen, D. (2012). An Inversion-Based Model Predictive Control with an Integral-of-Error State Variable for Piezoelectric-Actuators, IEEE/ASME Transactions on Mechatronics, . (Accepted) Cao, N., Chen, D. and Schreyer, D. (2012). Influence of Calcium Ions on Cell Survival and Proliferation in the Context of an Alginate Hydrogel, ISRN Chemical Engineering, 2012, 516461-9. Zheng, H., Tian, W.M., Yan, H.J., Yue, L., Zhang, Y., Han, F.T., Chen, D. and Li, Y. (2012). Rotary Culture Promotes the Proliferation of MCF-7 Cells Encapsulated in Three-Dimensional Collagen-Alginate Hydrogels via Activation of ERK1/2-MAPK Pathway, Biomedical Materials, 7(1), 01500301-01500310. Yan, X., Chen, D. and Bergstrom, D.J. (2011). Modeling of the flow within scaffolds in perfusion bioreactors, American Journal of Biomedical Engineering, 1(2), 72-77. Zhu, N., Chen, D., Chapman, D. and Cooper, D. (2011). X-ray Diffraction Enhanced Imaging as a Novel Method to Visualize Low Density Scaffolds in Soft Tissue Engineering, Tissue Engineering Part C, 17(11), 1071-1080. Li, M.G., Tian, X.Y., Schreyer, D.J. and Chen, D. (2011). Effect of Needle Geometry on Flow Rate and Cell Damage in the Dispensing-Based Biofabrication Process, Biotechnology Progress, 27(6), 1777-1784. Peng, J.Y. and Chen, D. (2011). Modeling of Piezoelectric Actuators Based on a New Rate-Independent Hysteresis Model, Modern Mechanical Engineering, 1(2), 25-30. Little, C.J., Bawolin, N.K. and Chen, D. (2011). Mechanical Properties of Natural Cartilage and Tissue Engineered Constructs, Tissue Engineering Part B, 17(4), 213-227. Wang, M.D., Zhai, P., Chen, D., Schreyer, D.J., Xun, X.D. and Cui, F.Z. (2011). Bioengineered Scaffolds for Spinal Cord Repair," Tissue Engineering Part B, Tissue Engineering Part B, 17(3), 177-194. Zhu, N., Li, M.G., Cooper, D. and Chen, D. (2011). Development of Novel Hybrid Poly (L-lactide)/Chitosan Scaffolds Using Rapid Freeze Prototyping Technique, Biofabrication, 3(3), 034105-034113. Li, M.G., Tian, X.Y. and Chen, D. (2011). Temperature Effect on the Shear-Induced Cell Damage in Biofabrication, Artificial Organs, 35(7), 741-746. Zhang, Z.M., An, Q., Zhang, W.J., Yang, Q., Tang, Y.J. and Chen, D. (2011). Modeling of Directional Friction on a Fully Lubricated Surface with Regular Anisotropic Asperities, Meccanica, 46(3), 535-545. Bai, X.P., Zheng, H.X., Fang, R., Wang, T.R., Hou, X.L., Li, Y., Chen, D. and Tian, W.M. (2011). Fabrication of Engineered Heart Tissue Grafts from Alginate/Collagen Barium Composite Microbeads, Biomedical Materials, 6(4), 045002-045011. Peng, J.Y. and Chen, D. (2011). Modeling of Piezoelectric-Driven Stick-Slip Actuators, IEEE/ASME Transactions on Mechatronics, 16(2), 394-399. Li, J.W., Chen, D. and Zhang, W. (2011). Axiomatic Design Theory Based Approach to Modeling Linear High Order System Dynamics, IEEE/ASME Transactions on Mechatronics, 16(2), 341-350. Bawolin, N.K., Li, M.G., Chen, D. and Zhang, W. (2010). Modeling Material-Degradation-Induced Elastic Property of Tissue Engineering Scaffolds, ASME Journal of Biomechanical Engineering, 132(11), 111001-7. Zhu, N., Chen, D. and Chapman, D. (2010). A Brief Review of Visualization Techniques for Nerve Tissue Engineering Applications, Journal of Biomimetics, Biomaterials, and Tissue Engineering, 7, 81-99. Li, J.W., Matias, E., Chen, N., Kim, C.Y., Wang, J., Gorin, J., He, F., Thorpe, P., Lu, Y., Chen, W.F., Grochulski, P., Chen, D. and Zhang, W. (2010). Investigations of Mechanical Vibrations for beamlines at the Canadian Light Source, Journal of Synchrotron Radiation, 18, 109-116. Zhu, N., Li, M.G., Guan, Y.J., Schreyer, D.J. and Chen, D. (2010). Effect of Laminin Blended with Chitosan on Axon Guidance on Patterned Substrates, Biofabrication, 2, 045002-045009. Bawolin, N.K., Zhang, W. and Chen, D. (2010). A Brief Review of the Modelling of the Time Dependent Mechanical Properties of Tissue Engineering Scaffolds, Journal of Biomimetics, Biomaterials, and Tissue Engineering, 6, 19-33. Li, J.W., Chen, D. and Zhang, W. (2010). A New Approach to Modeling System Dynamics - in the Case of Piezoelectric Actuator with a Host System, IEEE/ASME Transactions on Mechatronics, 15(3), 371-380. Li, M.G., Tian, X.Y., Zhu, N., Schreyer, D.J. and Chen, D. (2010). Modeling Process-Induced Cell Damage in the Bio-Dispensing Process, Tissue Engineering Part C, 16(3), 533-42. Tian, X.Y., Li, M.G., Cao, N., Li, J.W. and Chen, D. (2009). Characterization of Flow Behaviours of Alginate/Hydroxyapaptite Mixtures for Tissue Scaffold Fabrication, Biofabrication, 1(4), 0450051-8. Li, M.G., Tian, X.Y. and Chen, D. (2009). A Brief Review of Dispensing-Based Rapid Prototyping Techniques in Tissue Scaffold Fabrication, Biofabrication, 1, 032001-032010.