Garnier, Alain - Université Laval - Département de génie chimique

个人简介

B. Ing., École Polytechnique de Montréal, 1985 M.Sc. génie chimique, École Polytechnique de Montréal, 1987 Ph.D. génie chimique, École Polytechnique de Montréal, 1992

近期论文

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Hoesli CA, Juneau PM, Chevallier P, Duchesne C, Garnier A, Laroche G (2014), "A fluorophore-tagged RGD peptide to control endothelial cell adhesion to micropatterned surfaces". Biomaterials, 35(3), 879-890. Segura MM, Mangion M, Gaillet B, Garnier A (2013), "New developments in lentiviral vector design, production and purification". Expert Opin Biol Ther, 13(7):987-1011. Juneau PM, Garnier A, Duchesne C (2013), "Selection and tuning of a fast and simple phase-contrast microscopy image segmentation algorithm for measuring myoblast growth kinetics in an automated manner". Microsc Microanal, 19(4), 855-866. Michaud FT, Havugimana PC, Duchesne C, Sanschagrin F, Bernier A, Lévesque RC, Garnier A (2012), "Cell culture tracking by multivariate analysis of raw LCMS data". Appl Biochem Biotechnol, 167(3):474-488. Leysi-Derilou Y, Duchesne C, Garnier A, Pineault N (2012), "Single Cell Level Analysis of Megakaryocyte Growth and Development". Differentiation, 83:200-209. Robert A, Cortin V, Garnier A, Pineault N (2012), "Megakaryocyte and platelet production from human cord blood stem cells". Methods Mol Biol, 788:219-247. Pineault N, Cortin V, Boyer L, Garnier A, Robert A, Thérien C, Roy DC (2010), "Individual and synergistic cytokine effects controlling the expansion of cord blood CD34+ cells and megakaryocyte progenitors in culture". Cytotherapy, 13(4):467-480. Gaillet B, Gilbert R, Broussau S, Pilotte A, Malenfant F, Mullick A, Garnier A, Massie B (2010), "High-level recombinant protein production in CHO cells using lentiviral vectors and the cumate gene-switch". Biotechnol Bioeng, 106(2):203-215. Leysi-Derilou Y, Robert A, Duchesne C, Garnier A, Boyer L, Pineault N (2010), « Polyploid megakaryocytes can complete cytokinesis ». Cell Cycle, 9(13):2587-2597. Caron AW, Nicolas C, Gaillet B, Ba I, Pinard M, Garnier A, Massie B, Gilbert R (2009), "Fluorescent labeling in semi-solid medium for selection of mammalian cells secreting high-levels of recombinant proteins". BMC Biotechnol, 9:42-52. Michaud, FT, Garnier, A, Lemieux, L, Duchesne, C (2008), "Multivariate analysis of single quadrupole LCMS spectra for routine characterization and quantification of intact proteins". Proteomics Proteomics, 9 (3):746-756. Segura MM, Garnier A, Di Falco MR, Whissell G, Meneses-Acosta A, Arcand N, Kamen A (2007), " Identification of host proteins associated with retroviral vector particles by proteomic analysis of highly purified vector preparations". J Virol, 82:1107-1117. Segura MM, Garnier A, Durocher Y, Coelho H, Kamen A (2007), "Production of Lentiviral Vectors by Large-Scale Transient Transfection of Suspension Cultures and Affinity Chromatography Purification". Biotechnol Bioeng, 98 (4), 789-799. Gilbert PA, Kamen A, Bernier A, Garnier A (2007), "A simple macroscopic model for the diffusion and adsorption kinetics of r-adenovirus". Biotechnol Bioeng., 98:239:251. Gaillet B, Gilbert R, Amziani R, Guilbault C, Gadoury C, Mullick A, Garnier A, Massie, B (2007), "High-level recombinant protein production in CHO cells using an adenoviral vector and the cumate gene-switch". Biotechnol Prog, 23(1):200-209. Paradis-Bleau C, Cloutier I, Lemieux L, Sanschagrin F, Laroche J, Auger M, Garnier A, Levesque R (2007), "Peptidoglycan lytic activity of the Pseudomonas aeruginosa phage PhiKZ gp144 lytic transglycosylase". FEMS Microbiol Lett, 266:201-209. Segura MM, Kamen A, Lavoie M-C, Garnier A (2007), "Exploiting heparin-binding properties of MoMLV-based retroviral vectors for affinity chromatography". J Chrom B, 846:124-131. Ghani K, Garnier A, Coelho H, Transfiguracion J, Trudel P, Kamen A (2005), "Retroviral vector production using suspension-adapted 293GPG cells in a 3L acoustic filter-based perfusion bioreactor". Biotechnol Bioeng, 95(4):653-660. Segura, MM, Garnier, A, Kamen, A (2006), "Purification and characterization of retrovirus vector particles by rate zonal ultracentrifugation". J Virol Methods, 133:82-91. Segura MM, Kamen A, Garnier A (2005), "Downstream processing of oncoretroviral and lentiviral gene therapy vectors". Biotechnol Adv, 24(3):321-337. Segura, MM, Kamen, A, Trudel, P, Garnier, A (2005), "A novel purification strategy for retrovirus gene therapy vectors using heparin affinity chromatography". Biotechnol Bioeng, 90(4):391-404. Michaud, FT, Parent, V, Garnier, A, Duchesne, C (2005), "On the Proper Use of Statistical Design of Experiments". Exp Hematol, 33(11):1271-1272. Cortin, V, Garnier, A, Pineault, N, Boyer, L, Lemieux, R, Proulx, C (2005), "Efficient In Vitro Megakaryocyte Maturation Using Cytokine Cocktails Optimized by Statistical Experimental Design". Exp Hematol, 33 (10): 1182-1191. Cortin, V, Thibault, J, Jacob, D, Garnier, A (2004), "Recombinant High-titer adenovirus vector production in 293S cell perfusion culture." Biotechnol Progress, 20(3):858-63. Jardon, M, Garnier, A (2003), "Effect of pH, PCO2, and Temperature on Recombinant Adenovirus Production". Biotechnol Prog, 19:202-208.