Maréchal, Alexandre - Université de Sherbrooke

个人简介

Ph. D. Biochimie, Université de Montréal (2009) Postdoctorat, Harvard Medical School, Massachusetts General Hospital Cancer Center (2010-2014)

近期论文

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Maréchal, A. et Zou, L. 2015. RPA-Coated Single-Stranded DNA As a Platform for Post-translational Modifications in the DNA Damage Response. Cell Research 25: 9-23. Maréchal, A. et Zou, L. 2014.A LARGe Surprise Links ATR and Rho. Cell Cycle 13: 3627. Wu, CS., Ouyang, J., Mori, E., Nguyen, HD., Maréchal, A., Hallet, A., Chen, DJ. et Zou, L. 2014. SUMOylation of ATRIP Potentiates DNA Damage Signaling by Boosting Multiple Protein Interactions in the ATR Pathway. Genes and Development 28: 1472-1484. Maréchal, A., Li, J-M, Ji, XY, Wu, CS., Yazinski, SA., Nguyen, HD., Liu, S., Jiménez, AE., et Zou, L. 2014. The PRP19 splicing factor transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry. Molecular Cell. 23: 235-246.