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Shkreta, L., Blanchette, M., Toutant, J., Wilhem, E., Bell, B., Story, B.A., Cochrane, A., Balachandran, A., Cheung, P.K., Harrigan, P.R., Grierson, D. and Chabot, B. (2016). Modulation of the splicing regulatory function of SRSF10 by a novel compound that impairs HIV-1 replication. Nucl. Acids. Res. doi: 10.1093/nar/gkw1223 PMID : 27928057 Shkreta, L., Toutant, J., Durand, M., Manley, J.L. and Chabot, B. (2016). The splicing regulator SRSF10 connects the DNA damage response to the alternative splicing of genes encoding components involved in apoptosis, cell-cycle and DNA repair. Cell Reports 17(8):1990-2003. doi :10:1016/j.celrep.2016.10.071 PMID : 27851963. Bondy-Chorney, E., Crawford, T.E., Ravel-Chapuis, A., Klinck, R., Chabot, B., Jasmin, B.J., and C?té, J. (2016). Staufen1 regulates multiple alternative splicing events either positively or negatively in DM1 indicating its role as a disease modifier. PLoS Genetics. 12(1): e1005827. doi:10.1371 / journal.pgen.1005827 PMID : 26824521. Cheung, P.K., Horant, D., Bandy, L.E., Zamiri, M., Rabea, S.M., Karagiosov, S.K., Matloobi, M., Harrigan, P. R., Chabot, B. and Grierson, D.S. (2016). A parallel synthesis approach leading to the identification of novel diheteroarylamide-based inhibitors of HIV alternative splicing: a new anti-HIV/AIDS strategy replication. J. Med. Chem. 59(5):1869-79 doi:10.1021 / acs.jmedchem.5b01357 PMID: 26878150. Chabot, B. and Shkreta, L. (2016). Defective control of pre-messenger RNA splicing in human disease. J. Cell. Biol. 212 (1):13-27. PMID: 26728853. Shkreta, L. and Chabot, B. (2015). The RNA splicing response to DNA damage. Biomolecules 5(4): 2935-2977. PMID : 26529031. Shkreta, L., Cloutier, A., Toutant, J., Vennin Rendos, H. and Chabot, B. (2015). Regulation of alternative splicing and the case of Bcl-x. Pak. J. Biochem. Mol. Biol. 48(2): 27-38. Bergeron, D., Pal, G., Beaulieu, Y.B., Chabot, B. and Bachand, F. (2015). Regulated intron retention and nuclear pre-mRNA decay contribute to PABPN1 autoregulation. Mol. Cell. Biol. 35(14) 2503-17. PMID: 25963658. Gabriel, M., Delforge, Y., Deward, A., Habraken, Y., Hennuy, B., Piette, J., Klinck, R., Chabot, B., Colige, A. and Lambert, C. (2015). Role of the splicing factor SRSF4 in cisplatin-induced modifications of pre-mRNA splicing and apoptosis. BMC Cancer. 15:227. doi: 10.1186/s12885-015-1259-0. PMID: 25884497. Lemieux, B., Blanchette, M., Monette, A., Mouland, A.J., Wellinger, R.J. and Chabot, B. (2015). A function for hnRNP A1 and A2 in transcription elongation. PLoS One. 10(5):e0126654. doi: 10.1371. PMID: 26011126. Chabot, B. (2015). My road to alternative splicing control: from simple paths to loops and interconnections. Biochem. Cell Biol. dx.doi.org/10.1139/bcb-2014-0161. PMID: 25759250. Chabot, B. (2015). Finding the rules of splicing and using them….alternatively. RNA 21: 582-583(invited essay for the 20th anniversary commemorative issue of the RNA journal). PMID : 25780148. Mauger, O., Klinck, R., Chabot, B., Muchardt, C., Allemand, E. and Batsché, E. (2015). Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions. Nucl. Acids Res. 43:1869-1882 PMID: 25605796. Best,A., James, K., Dalgliesh, C., Hong,E., Kheirolahi-Kouhestani, M., Curk, T., Xu, Y., Danilenko, M., Hussain, R., Keavney, B., Wipat, A., Klinck, R., Cowell, I., Lee, K. C., Austin, C., Venables, J., Chabot, B., Santibanez Koref, M., Tyson-Capper, A. and D. J. Elliott. (2014). Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons. Nature Comm. 5:4760 PMID:25208576 Klinck, R., Fourrier, A., Thibault, P., Toutant, J., Durand, M., Lapointe, E., Caillet-Boudin, M.-L., Sergeant, N.,Gourdon, G., Meola, G., Furling, D., Puymirat, J. and Chabot, B. (2014). RBFOX1 cooperates with MBNL1 to control splicing in muscle, including events altered in myotonic dystrophy type 1. PLoS One 9(9):e107324. PMID: 25211016 Brosseau, J.P., Lucier, J.F., Nwilati, H., Thibault, P., Garneau, D., Durand, M., Couture, S., Lapointe, E., Prinos, P., Klinck, R., Perreault, J.P., Chabot, B. and Abou Elela, S. (2014). Tumor microenvironment associated modifications of alternative splicing. RNA. 20:189-201. Brosseau, J.P., Lucier, J.F., Lamarche, A.A, Shkreta, L., Lapointe, E., Couture, S., Thibault, P., Gendron, D., Paquet, E., Perreault, J.P., Abou Elela, S. and Chabot, B. (2014). Redirecting splicing with bifunctional oligonucleotides. Nucl. Acids Res. 42(6):e40. Covered in Biotechniques. http://www.biotechniques.com/news/Snipping-and-Knitting-in-All-the-Right-Places/biotechniques-351323.html#.U1A488fxshl Venables, J.P., Lapasset, L., Gadea, G., Fort, P., Klinck, R., Irimia, M., Vignal, E., Prinos,P., Chabot, B., Abou Elela, S., Roux, P., Lemaitre, J.M. and Tazi, J. (2013). MBNL1 and RBFOX2 cooperate to change a splicing program involved in pluripotent stem cell differentiation. Nature Comm. 4:2480 doi: 10.1038/ncomms3480. Diaz, Z., Aguilar-Mahecha, A., Paquet, E.R., Basik, M., Orain, M., Camlioglu, E., Constantin, A., Benlimame, N., Bachvarov,, D., Jannot,, G., Simard, M.J., Chabot, B., Gologan, A., Klinck,R., Gagnon-Kugler, T., Lan,C., Przybytkowski, E., Qureshi, S., Rousseau,C., Spatz, A., Têtu,B., Batist, G. (2013). Next-generation biobanking of metastases to enable multidimensional molecular profiling in personalized medicine. Modern Pathology 26: 1413-1424. Shkreta, L., Bell, B., Revil, T., Venables, J.P., Prinos, P., Abou Elela, S. and Chabot, B. (2013). Cancer-associated perturbations in alternative pre-messenger RNA splicing. Cancer Treat Res. 158: 41-94. Venables, J.P., Brosseau, J.P., Gadea, G., Klinck, R., Prinos, P., Beaulieu, J.F., Lapointe, E., Durand, M., Thibault, P., Tremblay, K., Rousset, F., Tazi,J., Abou Elela, S. and Chabot, B. (2013). RBFOX2 is an important regulator of mesenchymal-specific splicing in both normal and cancer tissues. Mol. Cell. Biol. 33:396-405. Prinos, P., Klinck, R., Venables, J.P., Perreault, J.P., Wellinger, R.J., Abou Elela, S. and Chabot, B. (2012). Alternative splicing as a generator of functional diversity in cancer. MSA 1(4):151-165 [In French] Michelle, L., Barbier, J. and Chabot, B. (2012). hnRNP and hnRNP-like proteins in splicing control: molecular mechanisms and implication in human diseases. In RNA binding proteins, edited by Z. J. Lorkovic. Landes Biosciences. pp. 1-25. Lund, N., Milev, M.P., Wong, R., Sanmuganantham, T., Woolaway, K., Chabot, B., Abou Elela, S., Mouland, A.J., Cochrane, A. (2012). Differential effects of hnRNP D/AUF1 isoforms on HIV-1 gene expression. Nucl. Acids Res. 40(8):3663-3675. Michelle, L., Cloutier, A., Toutant, J., Shkreta, L., Thibault, P., Durand, M., Garneau, D., Gendron, D., Lapointe, E., Couture, S., Le Hir, H., Klinck, R., Abou Elela, S., Prinos, P. and Chabot, B.(2012). EJC components modulate the alternative splicing of Bcl-x and other apoptotic genes. Mol. Cell. Biol.32:954-967.

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