Breton, Sophie - Université de Montréal - Département de sciences biologiques

研究领域

My research program is integrative, using approaches including molecular biology, physiology, genomics, transcriptomics, proteomics and evolutionary biology to address the following questions: How do new species form? How do organisms adapt to their environment? My team is particularly interested to better understand the role of mitochondria and their genomes in speciation. In this perspective, my research aims at better understand the function, structure, expression, evolution and inheritance of mitochondrial genomes, the co-adaptation of mitochondrial and nuclear genomes and the physiological mechanisms of animal adaptation to environmental conditions

近期论文

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Guerra, D., Ghiselli, F., Minali, L., Breton, S., and Passamonti M. (2016) Early replication dynamics of sex-linked mitochondrial DNAs in the doubly uniparental inheritance species Ruditapes philippinarum (Bivalvia Veneridae). Heredity 116: 323-332. Minoiu, I., Burzynski, A., and Breton S. (2016) Analysis of the coding potential of the ORF in the control region of the female-transmitted Mytilus mtDNA. Gene 576: 586-588. Breton, S., and Stewart, D.T. (2015) Atypical mitochondrial inheritance patterns in eukaryotes. Genome 58: 423-431. Capt, C., Passamonti, M., and Breton, S. (2015) The human mitochondrial genome may code for more than 13 proteins. Mitochondrial DNA doi:10.3109/19401736.2014.1003924 Breton, S., Milani, L., Ghiselli, F., Guerra, D., Stewart, D.T., and Passamonti M. (2014) A resourceful genome: updating the functional repertoire and evolutionary role of animal mitochondrial DNAs. Trends Genet. 30: 555-564. Ghiselli, F., Milani, L., Guerra, D., Chang, P.L., Breton, S., Nuzhdin, S.V., and Passamonti M. (2013) Structure, transcription, and variability of metazoan mitochondrial genome: perspectives from an unusual mitochondrial inheritance system. Genome Biol. Evol. 5: 1535-1554. Milani, L., Ghiselli, F., Guerra, D., Breton, S., and Passamonti, M. (2013) A comparative analysis of mitochondrial ORFans: new clues on their origin and role in species with doubly uniparental inheritance of mitochondrial. Genome Biol. Evol. 5: 1408-1434. Yusa, Y., Breton, S., and Hoeh, W.R. (2013) Population genetics of sex determination in Mytilus mussels: re-analyses and a model. J. Hered. 104: 380-385. Stewart, D.T., Jha, M., Breton, S., Hoeh, W.R., and Blier, P.U. (2012) The effects of sperm competition and chemo-attractants on sperm velocity in Mytilus edulis (Bivalvia: Mytilidae). Can. J. Zool. 90: 1291-1296 Shepardson, S., Heard, W.H., Breton, S., and Hoeh, W.R. (2012) Light and transmission electron microscopy of two spermatogenic pathways and unimorphic sperm in Venustaconcha ellipsiformis (Conrad, 1836) (Bivalvia: Unionoida). Malacologia 55: 263-284. Moreira, S., Breton, S., and Burger, G. (2012) Unscrambling genetic information at the RNA level. WIREs RNA 3: 213-228. Breton, S., Ghiselli, F., Passamonti, M., Milani, L., Stewart, D.T., and Hoeh, W.R. (2011) Evidence for a fourteenth mtDNA-encoded protein in the female-transmitted mtDNA of marine mussels (Bivalvia: Mytilidae). PLoS ONE 6: 19365. Breton, S., Stewart, D.T., Shepardson, S., Trdan, R.J., Bogan, A.E., Chapman, E.G., Ruminas, A.J., Piontkivska, H., and Hoeh, W.R. (2011) Novel protein genes in animal mtDNA: a new sex determination system in freshwater mussels (Bivalvia: Unionoida)? Mol. Biol. Evol. 28: 1645-1659. Breton, S., Stewart, D.T., and Hoeh, W.R. (2010) Characterization of a mitochondrial ORF from the gender-associated mtDNAs of Mytilus spp. (Bivalvia: Mytilidae): identification of the "missing" ATPase 8 gene. Mar. Genomics 3: 11-18. Doucet Beaupré, H., Breton, S., Chapman, E.G., Blier, P.U., Bogan, A.E., Stewart, D.T., and Hoeh, W.R. (2010) Mitochondrial Phylogenomics of the Bivalvia (Mollusca): Searching for the Origin and Mitogenomic Correlates of Doubly Uniparental Inheritance of mtDNA. BMC Evol. Biol. 10: 50.