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个人简介

教育背景: 1987.8-1991.7,南开大学,化学系,学士 1991.9-1993.12,南大大学,高分子化学与物理,硕士 1994.9-1997.7,南开大学,高分子化学与物理,博士 工作经历: 2000.6-2002.6,天津大学,博士后 2008.8-2008.12,Virigina commonwealth University,化学与生物医药工程学院,访问学者 2012.3-2012.9,Floride State University,生命与工程学院,访问学者 2002.7-2013.6,天津大学,材料科学与工程学院,副教授 2013.6-至今,天津大学,材料科学与工程学院,教授 承担项目: 1.“多肽修饰的功能化外泌体共投递系统和对肿瘤的抑制研究”,天津市面上项目,2018~2021。 2.“肿瘤靶向外泌体的工程化构建及共投递microRNA/吉非替尼抑制分子靶向治疗耐药研究”,国家基金面上项目,2017~2020。 3.“煤矿充填用高分子材料研究”,校企横向合作项目,2015~2016。 4.“相选择性凝胶组装和凝胶化效应研究”,天津市面上项目,2014~2015。 5.“新型含硫,硒螺噁嗪类光致变色材料合成和应用研究”,国家基金面上项目,2012~2013。 6.“新型有机光电材料的研究与开发”,校企横向合作项目,2010~2012。 7. “新型复合功能高分子材料的研制和开发”,校企横向合作项目,2010~2012。 8.“新型自粘防水卷材改性研究”,校企横向合作项目,2010。 9.“镀锌钢材表面装饰漆的优化及性能研究”,校企横向合作项目,2007。 代表性著作: 《材料科学基础》,靳正国,郭瑞松,侯信,师春生,天津大学出版社,2015.

研究领域

肿瘤靶向外泌体的共投递,药物辅料设计与合成,高分子复合材料

近期论文

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Microstructure-united heterogeneous sodium alginate doped injectable hydrogel for stable hemostasis in dynamic mechanical environments Yuwei Zhou , Meiru Li , Weicheng Gao , Xueping Li , Lixia Long , Xin Hou , Jin Zhao , Sidi Li , Xubo Yuan International Journal of Biological Macromolecules,Volume 248, 1 September 2023, 125877 Highly stretchable, injectable hydrogels with cyclic endurance and shape-stability in dynamic mechanical environments, by microunit reformation Journal of Materials Chemistry B 2023 | Journal article DOI: 10.1039/D2TB02738K CONTRIBUTORS: Meiru Li; Yuwei Zhou; Xueping Li; Sidi Li; Jin Zhao; Xin Hou; Xubo Yuan Entangled, Hofmeister effect‐enhanced macromolecular adhesives for effective bonding in dynamic seawater Sun Peng,Wang Qingxi,Wang Yongyu,Yuan Xubo,Zhao Jin,Long Lixia,Li Sidi,Hou Xin ISSN:0947-6539 2023 Container-title:Chemistry – A European Journal A Quenched Double‐Hydrophilic Coating for the Enhancement of Water Retention of Hydrogels Advanced Functional Materials 2023-08 | Journal article DOI: 10.1002/adfm.202303306 CONTRIBUTORS: Weicheng Gao; Jie Chang; Xueping Li; Sidi Li; Yuwei Zhou; Xin Hou; Lixia Long; Jin Zhao; Xubo Yuan Synthesis of magnetic NaY zeolite for plasma proteomics application Xiaodong Zhu , Congcong Ma , Xubo Yuan , Jin Zhao , Xin Hou https://doi.org/10.1016/j.mtcomm.2023.106219 SCIMP: A Novel Targeted Gene for Postmenopausal Osteoporosis Progression Orthopaedic Surgery 2023-05 | Journal article DOI: 10.1111/os.13715 CONTRIBUTORS: Xiaolei Sun; Aixian Tian; Peng Li; Jin Zhao; Xin Hou; Xinlong Ma; Xubo Yuan Sequential Delivery of Different MicroRNA Nanocarriers Facilitates the M1-to-M2 Transition of Macrophages ACS Omega 2022-03-08 | Journal article DOI: 10.1021/acsomega.2c00297 CONTRIBUTORS: Xueping Li; Suling Xue; Qi Zhan; Xiaolei Sun; Ning Chen; Sidi Li; Jin Zhao; Xin Hou; Xubo Yuan Phosphatidylcholine‐Engineered Exosomes for Enhanced Tumor Cell Uptake and Intracellular Antitumor Drug Delivery Macromolecular Bioscience 2021-08 | Journal article DOI: 10.1002/mabi.202100042 CONTRIBUTORS: Qi Zhan; Kaikai Yi; Xueping Li; Xiaoteng Cui; Eryan Yang; Ning Chen; Xubo Yuan; Jin Zhao; Xin Hou; Chunsheng Kang Bioinspired Double‐Dynamic‐Bond Crosslinked Bioadhesive Enables Post‐Wound Closure Care Advanced Functional Materials 2020-04 | Journal article DOI: 10.1002/adfm.202000130 CONTRIBUTORS: Sidi Li; Ning Chen; Xueping Li; Yang Li; Zhipeng Xie; Zhenyu Ma; Jin Zhao; Xin Hou; Xubo Yuan Environment‐Dependent Adhesive Behaviors of Mussel‐Inspired Coordinate‐Crosslinked Bioadhesives Macromolecular Materials and Engineering 2020-01 | Journal article DOI: 10.1002/mame.201900620 CONTRIBUTORS: Sidi Li; Ning Chen; Yang Li; Jin Zhao; Xin Hou; Xubo Yuan MiR-21 nanocapsules promote early bone repair of osteoporotic fractures by stimulating the osteogenic differentiation of bone marrow mesenchymal stem cells Journal of Orthopaedic Translation 2020-09 | Journal article DOI: 10.1016/j.jot.2020.04.007 CONTRIBUTORS: Xiaolei Sun; Xueping Li; Hongzhao Qi; Xin Hou; Jin Zhao; Xubo Yuan; Xinlong Ma A sorbitol‐based phase‐selective organogelator for crude oil spills treatment Journal of Applied Polymer Science 2019-02-10 | Journal article DOI: 10.1002/app.47052 CONTRIBUTORS: Cailing Zhuan; Yun Li; Xubo Yuan; Jin Zhao; Xin Hou Sidi Li, Ning Chen, Yang Li, Xueping Li, Qi Zhan, Jiamin Ban, Jin Zhao*,Xin Hou, Xubo Yuan. Metal-crosslinked ɛ-poly-L-lysine Tissue Adhesives with High Adhesive Performance: Inspiration from Mussel Adhesive Environment. International Journal of Biological Macromolecules,2020, 153: 1251-1261.IF=4.784 Ying Du,Xin Hou*, Jin Zhao*, Xubo Yuan. Effect of Neutralization on Physicochemical/Mechanical Properties of Hydroxypropylmethylcellulose Acetate Succinate. Materials Chemistry and Physics,2020, 249: 122963.IF=2.781 Qi Zhan, Kaikai Yi, Hongzhao Qi, Sidi Li, Xueping Li, Qixue Wang, Yunfei Wang, Chaoyong Liu, Mingzhe Qiu, Xubo Yuan, Jin Zhao*,Xin Hou*, Chunsheng Kang*, Engineering blood exosomes for tumor-targeting efficient gene/chemo combination therapy. Theranostics,2020, doi:10.7150/thno.45028. IF=8.063, TOP期刊 Sidi Li, Luyang Chen, Kai Huang, Ning Chen, Qi Zhan, Kaikai Yi, Hongzhao Qi, Chaoyong Liu, Yanli Tan,Xin Hou, Yunfeng Lu, Jin Zhao*, Xubo Yuan*, Chunsheng Kang*. Tumor Microenvironment‐Tailored Weakly Cell‐Interacted Extracellular Delivery Platform Enables Precise Antibody Release and Function. Advanced Functional Materials,2019: 1903296.IF=15.621, TOP期刊 Yang Lijun, Han Donglin, Zhan Qi, Li Xueping, Zhao Jin,Hou Xin, Yuan Xubo*, Qi Hongzhao*,Blood TfR plus exosomes separated by a pH-responsive method deliver chemotherapeutics for tumor therapy, Theranostics, 2019,9(25):7680-7696 IF=8.063, TOP期刊

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