XIE, Jianping - National University of Singapore - Department of Chemical and Biomolecular Engineering

个人简介

Education 07.2003 – 12.2007 PhD in Molecular Engineering of Biological and Chemical Systems (MEBCS), Singapore-MIT Alliance (SMA) 07.1999 – 06.2002 MS in Chemical Engineering, Tsinghua University, China 09.1995 – 06.1999 BS in Chemical Engineering, Tsinghua University, China Employment History 01.2023 Professor, Department of Chemical & Biomolecular Engineering, NUS 01.2017 – 12.2022 Associate Professor (Dean’s Chair), Department of Chemical & Biomolecular Engineering, NUS 07.2010 – 12.2016 Assistant Professor, Department of Chemical & Biomolecular Engineering, NUS 02.2010 – 07.2010 Visiting Scientist, Department of Materials Science and Engineering, MIT 01.2008 – 12.2009 Postdoctoral Fellow, Institute of Bioengineering and Nanotechnology (IBN), A*STAR, Singapore

研究领域

(a) Overarching Theme: Engineering noble metal nanoclusters for biomedical and catalytic applications (b) Research Contributions: Dr. Xie is well known for his seminal works on subnanometer-sized metal nanoclusters, an emerging class of functional materials for biomedical and catalytic applications. He is pivotal in developing a number of novel pathways for the synthesis of fluorescent and atomically precise metal nanoclusters, all of which are now widely used in the nanocluster community. Dr. Xie was the first to propose the concept of “total synthesis” for metal nanoclusters, revealing the formation chemistry of metal nanoclusters at the atomic level and elucidating the luminescence fundamentals of metal nanoclusters at the molecular level. On the application front, Dr. Xie pioneered the design of metal nanocluster radiosensitizers for cancer radiotherapy and traceable antimicrobial agents. Dr. Xie’s publications in prestigious journals and keynote/invited talks at international conferences on materials, chemistry and chemical engineering over the past nine years have raised NUS’ global reputation in contributions to research on noble metal nanoclusters. Specific contributions are elaborated below:

近期论文

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Surface Dynamics Promoted Supercrystal Engineering of Atomically Precise Gold Nanoparticles.Q Yao#, L Liu#, S Malola#, M Ge, H Xu, Z Wu, T Chen, Y Cao, M Matus, A Pihlajamäki, Y Han* H. Häkkinen, J Xie* Accepted by Nature Chemistry. Achieving efficient and stable electrochemical nitrate removal by in-situ reconstruction of Cu2O/Cu electroactive nanocatalysts on Cu foam.J Zhou, F Pan, Q Yao, Y Zhu*, H Ma, J Niu, J Xie*.Applied Catalysis B: Environmental 2022, 317, 121811. Identification of Chemical Compositions from “Featureless” Optical Absorption Spectra: Machine Learning Predictions and Experimental Validations.T Chen, J Li, P Cai, Q Yao, Z Ren, Y Zhu, S Khan, J Xie*, X Wang*. Nano Research, accepted. Gold nanocluster with AIE: A novel photodynamic antibacterial and deodorant molecule.H Zhu, S Wang, Y Wang, C Song, Q Yao, X Yuan, J Xie* Biomaterials 2022, 288, 121695. Aggregation-Induced Emission of Gold Nanoclusters by Ionic Liquids for White Light-Emitting Diode and Multiple-Ion Probe Applications.M Zhu, Q Yao*, Z Liu, J Liu, M Liu, M Long, J Xie* The Journal of Physical Chemistry Letters 2022, 13, 7722-7730. Bis-Schiff base linkage-triggered highly bright luminescence of gold nanoclusters in aqueous solution at the single-cluster level.H Deng, K Huang, L Xiu, W Sun, Q Yao, X Fang, X Huang, J Xie* W Chen*. Nature Communications 2022,13, 1-9. Interactions of metal nanoclusters with light: fundamentals and applications.T Chen, H Lin, Y Cao, Q Yao, J Xie*. Advanced Materials 2022, 34, 2103918. Atomic-precision Pt6 nanoclusters for enhanced hydrogen electro-oxidation.X Wang, L Zhao, X Li, Y Liu, Y Wang, Q Yao, J Xie, Q Xue, Z Yan, X Yuan*, W Xing*. Nature Communications 2022, 13, 1-10. Atom-precision engineering chemistry of noble metal nanoparticles.Q Yao, Q Zhang, J Xie* Industrial & Engineering Chemistry Research 2022, 61, 7594-7612. In Situ Synthesis of Bismuth Nanoclusters within Carbon Nano‐Bundles from Metal–Organic Framework for Chloride‐Driven Electrochemical Deionization.Y Liu, L Wang, Q Yao, X Gao, X Du, X Dou, H Zhu, X Yuan*, J Xie* Advanced Functional Materials 2022 32, 2110087. Zn‐MOFs Derived Ordered Mesoporous Carbon‐based Nanostructure for High‐performance and Universal Multivalent Metal Ion Storage.H Zhang, H Wang, Z Pan, Z Wu, Y Deng, J Xie*, J Wang, X Han, W Hu* Advanced Materials, 2022, 2206277. Cation polymer-induced aggregation of water-soluble Au (i)–thiolate complexes and their photoluminescence properties.N Hao, Y Cao, R Li, H Lin, H Shan, T Chen, OJH Chai, Q Yao, X Chen, J Xie* Chemical Communications 2022 58, 8234-8237 Gold nanocluster based nanocomposites for combinatorial antibacterial therapy for eradicating biofilm forming pathogens.YG Srinivasulu, A Mozhi, N Goswami, Q Yao, J Xie* Materials Chemistry Frontiers 2022, 6, 689-706. Revealing the composition-dependent structural evolution fundamentals of bimetallic nanoparticles through an inter-particle alloying reaction.Y Lin, Y Cao, Q Yao, J Xie* Chemical Science 2022 13, 4598-4607. Enhancing catalytic properties of ligand-protected gold-based 25-metal atom nanoclusters by silver doping.RR Nasaruddin, MJ Hülsey, J Xie* Molecular Catalysis 2022 518, 112095 Surface engineering assisted size and structure modulation of gold nanoclusters by ionic liquid cations. Zhu, M.; Yao, Q.;* Liu, Z.; Zhang, B.; Lin, Y.; Liu, J.; Long, M.; Xie, J.* Angewandte Chemie – International Edition 2021. In situ synthesis of bismuth nanoclusters within carbon nano-bundles from metal-organic framework for chloride-driven electrochemical deionization Liu, Y.; Wang, L.; Yao, Q.; Gao, X.; Du, X.; Dou, X.; Zhu, H.; Yuan, X.;* Xie, J.*Advanced Functional Materials 2021, 2110087 Diversification of metallic molecules through derivatization chemistry of Au25 nanoclusters Cao, Y.; Chen, T.; Yao, Q.; Xie, J.*Accounts of Chemical Research 2021, 54, 4142 Cluster materials as traceable antibacterial agents Zheng, K.; Xie, J.* Accounts of Materials Research 2021, 2, 1104 All hydroxyl-thiol-protected gold nanoclusters with near-neutral surface charge Chai, O. J. H.; Wu, Z.; Xie, J.* Journal of Physical Chemistry Letters 2021, 12, 9882 The bright future of gold nanoclusters in theranostics Cifuentes-Rius, A.;* Deepagan, V. G.; Xie, J.; Voelcker, N. H.* ACS Applied Materials & Interfaces 2021, 13, 49581 Engineering metal nanoclusters for targeted therapeutics: from targeting strategies to therapeutic applications Lin, Z.; Goswami, N.; Xue, T.; Chai, O. J. H.; Xu, H.; Liu, Y.; Su, Y.; Xie, J.* Advanced Functional Materials 2021, 2105662. Interactions of metal nanoclusters with light: fundamentals and applications Chen, T.; Lin, H.; Cao, Y.; Yao, Q.; Xie, J.* Advanced Materials 2021, 2103918 Shining photocatalysis by gold-based nanomaterials Zhu, H.; Yuan, X.;* Yao, Q.;* Xie, J.* Nano Energy 2021, 106306 Reversible isomerization of metal nanoclusters induced by intermolecular interaction Cao, Y.; Malola, S.; Matus, M. F.; Chen, T.; Yao, Q.; Shi, R.; Häkkinen, H.;* Xie, J.* Chem 2021, 7, 2227 Revealing the etching process of water-soluble Au25 nanoclusters at the molecular level Cao, Y.; Liu, T.; Chen, T.; Zhang, B.; Jiang, D. -e.; Xie, J.* Nature Communications2021, 12, 3212. Electrocatalysis of gold-based nanoparticles and nanoclusters Li, C.; Chai, O. J. H.; Yao, Q.; Liu, Z.; Wang, L.;* Wang, H.;* Xie, J.* Materials Horizons 2021, 8, 1657. Confined unimolecular micelles for precisely controlled in-situ synthesis of stable ultra-small metal nanoclusters assemblies Zhang, W.; Kong, H.; Wu, Z.; Yao, Q.; Wang, L.; Qiao, L.; He, Y.; Qiao, X.;* Pang, X.;* Xie, J.* Chemistry of Materials 2021, Traceable nanocluster-prodrug conjugate for chemo-photodynamic combinatorial therapy of non-small cell lung cancer Srinivasulu, Y. G.; Mozhi, A.; Goswami, N.; Yao, Q.; Xie, J.* ACS Appl. Bio Mater. 2021, 4, 4, 3232–3245. High-Yield Synthesis of AIE-Type Au22(SG)18 Nanoclusters through Precursor Engineering and Its pH-Dependent Size Transformation. Srinivasulu, Y. G.; Goswami, N.; Yao, Q.; Xie, J.* The Journal of Physical Chemistry C 2021, 125, 4066. Multi-scale assembly of [AgS4] tetrahedrons into hierarchical Ag-S networks for robust photonic water Wu, Z.; Yao, Q.; Liu, Z.; Xu, H.;* Guo, P.; Liu, L.; Han, Y.; Zhang, K.; Lu, Z.; Li, X.; Zhang, J.; Xie, J.* Advanced Materials 2021, 33, 2006459 Ultra-stable hydrophilic gold nanoclusters protected by sulfonic thiolate ligands Zhang, B.; Wu, Z.; Cao, Y.; Yao, Q.; Xie, J.* Journal of Physical Chemistry C2021, 125, 489. Luminescent metal nanoclusters: biosensing strategies and bioimaging applications Xiao, Y.; Wu, Z.; Yao, Q.;* Xie, J.* Aggregate 2021, 2, 114. Correlations between the fundamentals and applications of ultrasmall metal nanoclusters: recent advances in catalysis and biomedical applications Liu, Z.; Wu, Z.; Yao, Q.; Cao, Y.; Chai, O. J. H.; Xie, J.* Nano Today 2021, 36, 101053 Ligand design in ligand-protected gold nanoclusters. Zhang, B.; Chen, J.; Cao, Y.; Chai, O. J. H.; Xie, J.* Small 2021, 2004381.