Abbott, Nicholas L. - Cornell University - Smith School of Chemical and Biomolecular Engineering

个人简介

EDUCATION Postdoc., Chemistry, Harvard University (1993) PhD, Chemical Engineering, Massachusetts Institute of Technology (1991) B Eng (Chemical), University of Adelaide, Australia (1986)

研究领域

RESEARCH INTERESTS interfacial phenomena colloid science soft materials biomolecular interfaces polymers, liquid crystals and surfactant hydrophobic effect

近期论文

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PUBLICATIONS Wang, X.; Miller, D.S.; Bukusoglu, E.; de Pablo, J.J.; Abbott, N.L., “Topological Defects in Liquid Crystals as Templates for Molecular Self-Assembly” Nature Materials, 15, 106-112, 2016 Ma, C.D.; Wang, C.; Acevedo-Vélez, C.; Gellman, S.H.; Abbott, N.L., “Modulation of Hydrophobic Interactions by Proximally Immobilized Ions”, Nature,517 (7534), 347-443, 2015 Mushenheim, P.C.; Abbott, N.L.; “Hierarchical Organization in Liquid Crystal-in-Liquid Crystal Emulsions”, Soft Matter, 10 (43), 8627-8634, 2014 Bai, Y.; Abbasi, R.; Wang, C.; Abbott, N.L.; “Liquid Crystals Anchored on Mixed Monolayers of Chiral versus Achiral Molecules: Continuous Change in Orientation as a Function of Enantiomeric Excess”, Angewandte Chemie, Int Ed, 53(31), 8079-8083, 2014 Mushenheim, P.C.; Trivedi, R.R.; Weibel, D.B.; Abbott, N.L., “Using Liquid Crystals to Reveal How Mechanical Anisotropy Changes Interfacial Behaviors of Motile Bacteria”, Biophysical Journal, 107(1), 255-265, 2014 Miller, D.; Wang, X.; Buchen, J.; Lavrentovich, O.; Abbott, N.L., “Analysis of the Internal Configurations of Droplets of Liquid Crystal using Flow Cytometry”, Analytical Chemistry, 85(21), 10296-10303, 2013 Bai, Y.; Abbott, N.L.; “Enantiomeric Interactions between Liquid Crystals and Organized Monolayers of Tyrosine-Containing Dipeptides”, Journal of American Chemical Society, 134(1), 548-558, 2012. Abras, D.; Pranami, G.; Abbott, N.L., “The Mobilities of Micro- and Nano-Particles at Interfaces of Nematic Liquid Crystals", Soft Matter, 8, 2026-2035, 2012. Carlton, Rebecca J.; Ma, C. Derek; Gupta, Jugal K.; Abbott, N.L., “Influence of Specific Anions on the Orientational Ordering of Thermotropic Liquid Crystals at Aqueous Interfaces”, Langmuir 28(35), 12796-12805, 2012. Muller, J. P. E.; Aytar, B. S.; Kondo, Y.; Lynn, D. M.; Abbott, N. L., “Incorporation of DOPE into lipoplexes formed from a ferrocenyl lipid leads to inverse hexagonal nanostructures that allow redox-based control of transfection in high serum.” Soft Matter 8(24), 6608-6619, 2012. Lin, I-H.; Miller, D.S.; Bertics, P.J.; Murphy, C.J.; de Pablo, J.J.; Abbott, N.L.; “Endotoxin-Induced Structural Transformations in Liquid Crystalline Droplets”, Science, 332(6035), 1297-1300, 2011. Bai, Y.; Abbott, N.L.; “Recent Advances in Colloidal and Interfacial Phenomena Involving Liquid Crystals”, Langmuir, 27(10), 5719-5738, 2011. Liu, X; Abbott, N.L. “Lateral Transport of Solutes in Microfluidic Channels using Electrochemically Generated Gradients in Redox-Active Surfactants”, Analytical Chemistry, 83(8), 3033-3041, 2011. Acevedo-Vélez;, C.; Andre, G.; Dufrene, Y.; Gellman, S.; Abbott, N.L., “Single Molecule Force Spectroscopy of ß-Peptides that Display Well-Defined Three-Dimensional Chemical Nanopatterns”, Journal of American Chemical Society, 133(11), 3981-3988, 2011. Liu, X.; Abbott, N.L, “Characterization of the Nanostructure of Complexes Formed by Single- or Double-Stranded Oligonucleotides with a Cationic Surfactant”, J. Phys. Chem. B, 114 (47), 15554-15564, 2010. Kinsinger, MI; Lynn, DM; Abbott, NL “Nematic Ordering Drives the Phase Separation of Mixed Monolayers Containing Phospholipids Modified with Poly(ethylene glycol) at Aqueous-Liquid Crystal Interfaces” Soft Matter, 6(17), 4095-4104, 2010. Koenig, GM; Lin, IH; Abbott, NL “Chemoresponsive Assemblies of Microparticles at Liquid Crystalline Interfaces”, Proceedings of the National Academy of Sciences, 107 (9), 3998-4003, 2010. Ankit Agarwal, Tahlia L. Weis, Michael J. Schurr, Nancy G. Faith, Charles J. Czuprynski, Jonathan F. McAnulty, Christopher J. Murphy, and Nicholas L. Abbott, “Surfaces Modified with Nanometer-Thick Silver-Impregnated Polymeric Films that Kill Bacteria but Support Growth of Mammalian Cells”, Biomaterials, 31(4), 680-690, 2010. Koenig GM, Ong R, Cortes AD, Moreno-Razo JA, de Pablo JJ, Abbott NL., Single Nanoparticle Tracking Reveals Influence of Chemical Functionality of Nanoparticles on Local Ordering of Liquid Crystals and Nanoparticle Diffusion Coefficients, Nanoletters, 9(7), 2794-2801, 2009. Liu, XY; Abbott, NL “Electrochemical Generation of Gradients in Surfactant Concentration Across Microfluidic Channels”, Analytical Chemistry, 81 (2), 772-781, 2009. Gupta, JK; Abbott, NL “Principles for Manipulation of the Lateral Organization of Aqueous-Soluble Surface-Active Molecules at the Liquid Crystal-Aqueous Interface” Langmuir, 25 (4), 2026-2033, 2009. Lowe, A.M., P.J. Bertics, and N.L. Abbott, “Quantitative Methods Based on Twisted Nematic Liquid Crystals for Mapping Surfaces Patterned with Bio/Chemical Functionality Relevant to Bioanalytical Assays”, Analytical Chemistry, 80(8), 2637-2645, 2008. Meli, Victoria, Lin, I.-H, and Nicholas L. Abbott, “Preparation of Microscopic and Planar Oil-Water Interfaces that are Decorated with Prescribed Densities of Insoluble Amphiphiles”, Journal of American Chemical Society, 130(13), 4326-4333, 2008. Claire L. Pizzey, Christopher M. Jewell, Melissa E. Hays, David M. Lynn and Nicholas L. Abbott, Yukishige Kondo, Sharon Golan and Yeshayahu Talmon, “Characterization of the Nanostructure of Complexes Formed by a Redox-Active Cationic Lipid and DNA”, Journal of Physical Chemistry B, in press 2008. Jugal K Gupta, Maria-Victoria Meli, Sarah Teren, and Nicholas L Abbott, “Elastic Energy-Driven Phase Separation of Phospholipid Monolayers at the Nematic Liquid Crystal-Aqueous Interface”, Physical Review Letters, 100, 048301-, 2008. Melissa E. Hays, Christopher M. Jewell, Yukishige Kondo, David M. Lynn, and Nicholas L. Abbott, “Lipoplexes Formed by DNA and Ferrocenyl Lipids: Effect of Lipid Oxidation State on Size, Internal Dynamics and Zeta-Potential”, Biophysical Journal, 93, 4414-4424, 2007. Govindaraju T, Bertics PJ, Raines RT, Abbott, N.L., “Using Measurements of Anchoring Energies of Liquid Crystals on Surfaces to Quantify Proteins Captured by Immobilized Ligands”, Journal of the American Chemical Society, 129 (36): 11223-11231, 2007. Liu XY, Graham MD, Abbott NL, “Methods for Generation of Spatial Gradients in Concentration of Monomeric Surfactants and Micelles in Microfluidic Systems”, Langmuir23 (19): 9578-9585, 2007. Jang, C.-H.; Cheng, L.-L.; Olsen, C. W.; Abbott, N. L. “Anchoring of Nematic Liquid Crystals on Viruses with Different Envelope Structures” NanoLetters, 6; 1053-1058, 2006. Nathan A. Lockwood, Jeffrey C. Mohr, Lin Ji, Christopher J. Murphy, Sean P. Palecek, Juan J. de Pablo, and Nicholas L. Abbott, “Thermotropic Liquid Crystals as Substrates for Imaging the Reorganization of Matrigel by Human Embryonic Stem Cells”, Advanced Functional Materials, 16, 618-624, 2006. Nathan A. Lockwood, Katie D. Cadwell, Frank Caruso, and Nicholas L. Abbott, “Formation of Polyelectrolyte Multilayer Films at Interfaces Between Thermotropic Liquid Crystals and Aqueous Phases”, Advanced Materials, 18: 850-855, 2006. Abbott NL, Jewell CM, Hays ME, Kondo Y, Lynn DM, “Ferrocene-Containing Cationic Lipids: Influence of Redox State on Cell Transfection”, Journal of American Chemical Society, 127 (33) 11576-11577, 2005. Clare BH, Abbott NL “Orientations of Nematic Liquid Crystals on Surfaces Presenting Controlled Densities of Peptides: Amplification of Protein-Peptide Binding Events”, Langmuir, 21 (14): 6451-6461, 2005. Brake, Jeffrey; Daschner, Maren; Abbott, Nicholas L. “Biomolecular Interactions at Phospholipid-Decorated Surfaces of Thermotropic Liquid Crystals”, Science, 302, 2094-2098, 2003. Luk, Yan-Yeung; Abbott, Nicholas L. “Surface-Driven Switching of Liquid Crystals using Redox- Active Groups on Electrodes”, Science, 301(5633), 623-626, 2003. Shah, R.; Abbott, N.L., “Principles for Measurement of Chemical Exposure based on Recognition-Driven Anchoring Transitions in Liquid Crystals, Science, 293, 1296-1299, 2001. Gu YD, Abbott NL, “Observation of Saturn-Ring Defects around Solid Microspheres in Nematic Liquid Crystals”, Physical Review Letters, 85, 4719-4722, 2000. Gallardo, B.S.; Gupta, V.K.; Jong, L.I.; Shah, R.; Eagerton, F.D.; Abbott, N.L., "Electrochemical Principles for Active Control of Liquids on Submillimeter Scales", Science, 283, 57-60, 1999. Gupta, V.K.; Dubrovsky, T.B.; Abbott, N.L., "Optical Amplification of Ligand-Receptor Binding Using Liquid Crystals", Science, 279, 2077-2080, 1998. Gupta, V.K.; Abbott, N.L., "Design of Surfaces for Patterned Alignment of Liquid Crystals on Planar and Curved Substrates", Science, 276, 1533-1536, 1997,