袁权 - 厦门大学 - 公共卫生学院

个人简介

主要学习经历： 2001-2005, 厦门大学, 生物科学, 理学学士 2005-2012, 厦门大学, 生物化学与分子生物学, 理学博士科研工作经历： 2009-至今, 厦门大学NIDVD, 病毒性肝炎研究组, 组长 2012-2015, 厦门大学公共卫生学院, 助理教授 2016-至今, 厦门大学公共卫生学院, 副教授

研究领域

1.乙型肝炎病毒治疗新药物的发展及转化医学研究 2.新型治疗性抗体发展及相关免疫学机制研究 3.乙型肝炎病毒免疫致病机制、分子流行特征与病毒进化规律研究 4.以精准医疗为目标的新型诊断试剂发展及转化医学研究 5.肝脏病原相关细胞及动物模型研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Zhang TY†, Yuan Q†*, Zhao JH, Zhang YL, Yuan LZ, Lan Y, Lo YC, Sun CP, Wu CR, Zhang JF, Zhang Y, Cao JL, Guo XR, Liu X, Mo XB, Luo LW, Cheng T, Chen YX, Tao MH, Shih, JWK, Zhao QJ, Zhang J, Chen PJ, Yuan YA*, Xia NS*. Prolonged suppression of hepatitis B virus in mice by a novel antibody that targets a unique epitope on HBsAg. Gut. 2015 Sep 30. pii: gutjnl-2014-308964. (Co-Corresponding/Co-First author) 2. Song LW, Wang YB, Fang LL, Wu Y, Yang L, Chen JY, Ge SX, Zhang J, Xiong YZ, Deng XM, Min XP, Zhang J, Chen PJ, Yuan Q*, Xia NS*.Rapid fluorescent lateral-flow immunoassay for hepatitis B virus genotyping. Anal Chem. 2015 May 19;87(10):5173-80. (*Co-Corresponding author) 3. Yuan Q†, Song LW†, Cavallone D, Moriconi F, Cherubini B, Colombatto P, Oliveri F, Coco BA, Ricco G, Bonino F, Shih JW, Xia NS, Brunetto MR. Total Hepatitis B Core Antigen Antibody, a Quantitative Non-Invasive Marker of Hepatitis B Virus Induced Liver Disease. PLoS One. 2015 Jun 26;10(6):e0130209. († Co-First Author) 4. Hou FQ, Song LW, Yuan Q, Fang LL, Ge SX, Zhang J, Sheng JF, Xie DY, Shang J, Wu SH, Sun YT, Wei SF, Wang MR, Wan MB, Jia JD, Luo GH, Tang H, Li SC, Niu JQ, Zhou WD, Sun L, Xia NS, Wang GQ. Quantitative hepatitis B core antibody level is a new predictor for treatment response in HBeAg-positive chronic hepatitis B patients receiving peginterferon. Theranostics. 2015 Jan 1;5(3):218-26. 5. Song LW, Liu PG, Liu CJ, Zhang TY, Cheng XD, Wu HL, Yang HC, Hao XK, Yuan Q*, Zhang J, Kao JH, Chen DS, Chen PJ*, Xia NS*. Quantitative hepatitis B core antibody levels in the natural history of hepatitis B virus infection. Clin Microbiol Infect. 2015 Feb;21(2):197-203. (*Co-Corresponding author) 6. Fan R†, Sun J†, Yuan Q†, Xie Q, Bai X, Ning Q, Cheng J, Yu Y, Niu J, Shi G, Wang H, Tan D, Wan M, Chen S, Xu M, Chen X, Tang H, Sheng J, Lu F, Jia J, Zhuang H, Xia N, Hou J. Baseline quantitative hepatitis B core antibody titre alone strongly predicts HBeAg seroconversion across chronic hepatitis B patients treated with peginterferon or nucleos(t)ide analogues. Gut. 2015 Jan 13. pii: gutjnl-2014-308546. († Co-First Author) 7. Yang H, Chen YZ, Zhang Y, Wang X, Zhao X, Godfroy JI, Liang Q, Zhang M, Zhang T, Yuan Q, Ann Royal M, Driscoll M, Xia NS, Yin H, Xue D. A lysine-rich motif in the phosphatidylserine receptor PSR-1 mediates recognition and removal of apoptotic cells. Nat Commun. 2015 Jan 7;6:5717. 8. Yuan Q, Song LW, Liu CJ, Li Z, Liu PG, Huang CH, Yan Y, Ge SX, Wang YB, Peng CY, Zhang J*, Kao JH, Chen DS, Chen PJ*, Xia NS*. Quantitative hepatitis B core antibody level may help predict treatment response in chronic hepatitis B patients. Gut. 2013 Jan;62(1):182-4. 9. Huang CH†, Yuan Q†, Chen PJ, Zhang YL, Chen CR, Zheng QB, Yeh SH, Yu H, Xue Y, Chen YX, Liu PG, Ge SX, Zhang J, Xia NS. Influence of mutations in hepatitis B virus surface protein on viral antigenicity and phenotype in occult HBV strains from blood donors. J Hepatol. 2012 Oct;57(4):720-9. († Co-First Author) 10. Geng X, Huang C, Qin Y, McCombs JE, Yuan Q, Harry BL, Palmer AE, Xia NS*, Xue D*. Hepatitis B virus X protein targets Bcl-2 proteins to increase intracellular calcium, required for virus replication and cell death induction. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18471-6. 11. Wang SH, Yeh SH*, Lin WH, Yeh KH, Yuan Q, Xia NS, Chen DS, Chen PJ. Estrogen Receptor-α Represses Transcription of HBV Genes via Interaction with Hepatocyte Nuclear Factor 4α. Gastroenterology. 2012 Apr;142(4):989-998.e4 12. Yuan Q, Cheng XD, Yang BC, Zheng QB, Chen YX, Chen QR, Zeng F, Zhang R, Ge SX, Hao XK, Chen H, Zhang J, Xia NS*. Differential diagnosis of pandemic (H1N1) 2009 infection by detection of haemagglutinin with an enzyme-linked immunoassay. Clin Microbiol Infect. 2011 Oct;17(10):1574-80. 13. Yu H†, Yuan Q†, Ge SX, Wang HY, Zhang YL, et al. Yu H, Yuan Q, Ge SX, Wang HY, Zhang YL, Chen QR, Zhang J*, Chen PJ, Xia NS. PLoS One. 2010 Feb 19;5(2):e9297.(†Co-First Author) 14. Yuan Q†, Ou SH†, Chen CR*, Ge SX, Pei B, Chen QR, Yan Q, Lin YC, Ni HY, Huang CH, Yeo AE, Shih JW, Zhang J*, Xia NS. Molecular Characteristics of Occult Hepatitis B virus from Blood donors in the southeast China. J. Clin. Microbiol. Feb. 2010, p. 357–362. († Co-First Author)