李中军 - 北京大学

个人简介

1982~1987年就读于北京医科大学药学院化学专业获理学学士学位，1987-1992年就读于北京医科大学药学院药物化学专业获药物化学博士学位，后留校任教从事教学和科研工作。1999年被聘为教授，2001年被聘为博士生导师。长期以来从事糖化学、糖化学生物学及相关创新药物的研究。先后获得了国家自然科学基金重大研究计划、重点课题、面上项目、科技部“973”、科技部创新药物重大专项、国家新药研究基金、卫生部科研基金、教育部创新团队等40余项基金的支持。已发表学术论文150余篇和专著一部，获批中国发明专利及国际专利20余项。担任中国药学会药物化学专业委员会委员，北京药学会药物化学专业委员会主任委员；为Chinese Chemical Letter、中国药物化学杂志、中国药学（英）等杂志编委。已指导研究生80余人获得学位。曾获国家教委科技进步三等奖及中国药学会-Servier青年药物化学奖。目前承担的课程有“有机合成”(药学院本科)、糖化学(药学院研究生)。先后获得北京大学“十佳教师”、“优秀教师”及医学部 “十佳教师”、研究生“良师益友”及“我身边的好老师”等称号。

研究领域

寡糖合成方法学及快速组装策略研究糖为手性源的天然产物和合成与活性研究基于糖的化学生物学研究创新药物研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Xiao Zhang, Huiying Liu, Lisha Lin, Wang Yao, Jinhua Zhao, Mingyi Wu*, Zhongjun Li*, Synthesis of Fucosylated Chondroitin Sulfate Nonasaccharide as a Novel Anticoagulant Targeting Intrinsic Factor Xase Complex. Angew. Chem. Int. Ed., 2018, 57, 12880. 2. Wei Li, Yu Gao, Qing Li, Zhongjun Li*, Ionic-liquid supported rapid synthesis of an N-glycan core pentasaccharide on a 10 g scale. Org. Biomol. Chem., 2018, 16, 4720. 3. Yanbo Liu, Wang Yao, Shuai Meng, Xiangbao Meng, Zhongjun Li*, Qinghua Lou*, A novel cobalt(0) alkyne complex assisted “capture and release” strategy for oligosaccharide rapid assembly. Org. Chem. Front. 2018, 5, 2098. 4. Xiao Zhang, Wang Yao, Xiaojiang Xu, MingYi Wu, Zhongjun Li*, Synthesis of fucosylated chondroitin sulfate glycoclusters: a robust route to novel anticoagulant agents. Chem. Eur. J., 2018, 24, 1694. 5. Yuan Guo, Inga Nehlmeier, Emma Poole, Chadams Sakonsinsiri, Nicole Hondow, Andy Brown, Qing Li, Shuang Li, Jessie Whitworth, Zhongjun Li, Anchi Yu, Rik Brydson, W. Bruce Turnbull, Stefan P？hlmann, Dejian Zhou. Dissecting Multivalent Lectin-Carbohydrate Recognition Using Polyvalent Multifunctional Glycan-Quantum Dots. J. Am. Chem. Soc., 2017, 139, 11833. 6. Shuai Meng, Tian Tian, Yunhe Wang, Xiangbao Meng, Zhongjun Li*, Convergent synthesis of oligosaccharides on the gram-scale using cetyl thioglycoside based on a hydrophobically assisted switching phase method. Org. Biomol. Chem., 2016, 14, 7722. 7. Shuai Meng, Tian Tian, Dong Han, Li-Na Wang, Shao-Geng Tang, Xiangbao Meng, Zhongjun Li*, Efficient assembly of oligomannosides using the hydrophobically assisted switching phase method. Org. Biomol. Chem., 2015, 13, 6711. 8. Wang Yao, Mengjie. Xia, Xiangbao Meng, Qing. Li*, Zhongjun Li*, Adaptable synthesis of C-lactosyl glycoclusters and its binding affinity with galectin-3, Org. Biomol. Chem., 2014, 11, 8180. 9. Xiaochao Xue, Zhaojun Yin, Xiangbao Meng, Zhongjun Li*, A Carbohydrate-Based Approach for the Total Synthesis of (-)-Dinemasone B,(+)-4a-epi-Dinemasone B,(-)-7-epi-Dinemasone B, and (+)-4a,7-Di-epi-dinemasone B. J. Org. Chem., 2013, 78, 9354.