个人简介
教育与科研经历
2011/01-至今 中国科学技术大学生命科学学院，副教授
2010/02-2010/12
英国Beatson研究所药物研发，副研究员
2008/05-2010/02 美国辉瑞公司博士后
2002/09–2008/05 约翰霍普金斯大学，博士
1999/09–2002/07 北京大学化学与分子工程学院，硕士
1995/09–1999/07 北京大学化学与分子工程学院，学士
研究领域
基于片段的药物先导化合物发现，核磁新方法的发展与应用。
近期论文
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1. Jia Gao#, E Liang#, Rongsheng Ma, Fudong Li, Yixiang Liu, Jiuyang Liu, Ling Jiang, Conggang Li, Haiming Dai, Jihui Wu, Xuncheng Su, Wei He, Ke Ruan*, Fluorine Pseudocontact Shifts Used for Characterizing the protein-Ligand Interaction Mode in the Limit of NMR Intermediate Exchange, Angew. Chem. Int. Ed., 2017, 56(42): 12982-12986
2. Difei Xu#, Rongsheng Ma, Jiahai Zhang, Zhijun Liu, Bo Wu, Junhui Peng, Yanan Zhai, Qingguo Gong, Yunyu Shi, Jihui Wu, Qiang Wu, Zhiyong Zhang*, Ke Ruan*, Dynamic Nature of CTCF Tandem 11 Zinc Fingers in Multivalent Recognition of DNA As Revealed by NMR Spectroscopy, J. Phys. Chem. Lett., 2018 9(14): 4020-4028
3. Difei Xu#, Bin Li#, Jia Gao#, Zhijun Liu, Xiaogang Niu, Gilbert Nshogoza, Jiahai Zhang, Jihui Wu, Xun-Cheng Su, Wei He, Rongsheng Ma*, Daiwen Yang*, Ke Ruan*, Ligand Proton Pseudocontact Shifts Determined from Paramagnetic Relaxation Dispersion in the Limit of NMR Intermediate Exchange, J. Phys. Chem. Lett., 2018, 9(12): 3361-3367
4. Jiuyang Liu#, Shuya Zhang#, Mingqing Liu, Yaqian Liu, Gilbert Nshogoza, Jia Gao, Rongsheng Ma, Yang Yang, Jihui Wu, Jiahai Zhang*, Fudong Li*, Ke Ruan*, Structural plasticity of the TDRD3 Tudor domain probed by a fragment screening hit, FEBS J. 2018, 285(11): 2091-2103
5. Rongsheng Ma#, Qingfeng Li, Aidong Wang, Jiahai Zhang, Zhijun Liu, Jihui Wu, Xuncheng Su*, Ke Ruan*, Determination of pseudocontact shifts of low-populated excited states by NMR chemical exchange saturation transfer, Phys. Chem. Chem. Phys. 2016, 18(20): 13794-13798
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