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个人简介

现为江南大学生物工程学院教授、博士生导师、教育部教授。2003年和2006年分别在江南大学发酵工程专业获硕士和博士学位。是北京大学、苏州大学兼职教授。在Nat Cata,Nat Comm,Chem Rev,ACS Cata,Metab Eng,Biotech Bioeng,微生物学报,生物工程学报等国内外生物工程类主流学术期刊上以第一或责任作者身份发表学术论文150余篇,其中SCI论文120余篇。出版科技著作3部。获得授权发明专利58项,申请或公开发明专利20余项。研究成果近5年来获国家技术发明二等奖、教育部科技进步一等奖、中国石油与化学工业联合会科技进步一等奖等5项科技奖励。其指导和培养的学生中,目前已有7人获江苏省优秀博士、硕士论文等奖励。 人才称号 2004年江苏省优秀硕士论文获得者 2005年江苏省"十佳"青年学生 2007年江苏省优秀博士学位论文获得者 2008年全国优秀博士学位论文获得者 2009年入选霍英东教育基金会高等院校青年教师基金获得者 2010年入选教育部新世纪优秀人才计划 2011年入选江苏省"六大人才高峰"高层次人才项目 2012年江苏省杰出青年基金获得者 2013年入选中组部首批"青年拔尖人才"支持计划 2014年国家自然科学基金优秀青年基金获得者 2016年江苏省333工程第二层次人选 2016年第十五届江苏省青年科技奖获得者 2017年教育部高层次人才 2017年科技创新领军人才

研究领域

研究方向为微生物制造工程。致力于解析生物加工过程中生物体(微生物/酶)的生理特性和调控机制,发展强化生产性能的新技术和新方法,以创建新一代工业菌株和性能先进的酶制剂,提升生物制造过程的效能,实现生物技术产品的低成本制造 主要研究内容包括 (1)新一代工业生产菌株改造与创制 (2)新型生物催化剂设计与催化过程创建 (3)工业发酵过程优化与放大

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Dengke Gao(高登科), Wei Song, Jing Wu, Liang Guo, Cong Gao, Jia Liu, Xiulai Chen, Liming Liu*. Efficient Production of L-homophenylalanine by Enzymatic–Chemical Cascade Catalysis[J]. Angewandte Chemie International Edition, 2022, accept. Kuo Zhao(赵阔), Jianmin Liu, Cong Gao, Jia Liu, Xiulai Chen, Liming Liu, Liang Guo*. Advances in microbial production of feed amino acid[J]. Advances in Applied Microbiology, 2022, accept. Jie Liu(刘洁), Jianmin Liu, Liang Guo , Jia Liu, Xiulai Chen, Liming Liu, Cong Gao*. Advances in microbial synthesis of bioplastic monomers[J]. Advances in Applied Microbiology, 2022, accept. Xin Meng(孟欣), Liming Liu, Xiulai Chen*. Bacterial photosynthesis: state-of-the-art in light-driven carbon fixation in engineered bacteria[J]. Current Opinion in Microbiology, 2022, 69:102174. Yu Yan(燕宇), Jing Wu, Guipeng Hu, Cong Gao, Liang Guo, Xiulai Chen, Liming Liu, Wei Song*. Current state and future perspectives of cytochrome P450 enzymes for C-H and C=C oxygenation[J]. Synthetic and Systems Biotechnology, 2022, 7(3): 887-899. Na Qi(齐娜), Jianmin Liu, Wei Song, Jia Liu, Cong Gao, Xiulai Chen, Liang Guo, Liming Liu, Jing Wu*. Rational design of phospholipase D to improve the transphosphatidylation activity for phosphatidylserine synthesis[J]. Journal of Agricultural and Food Chemistry, 2022, 70(22): 6709-6718. Cong Gao(高聪), Liang Guo, Wei Song, Jing Wu, Xiulai Chen, Liming Liu*. Advances in microbial engineering for the production of value-added products in a biorefinery[J]. Systems Microbiology and Biomanufacturing, 2022, accept. Zuwei Xu(徐祖伟), Lihao Ji, Wenxiu Tang, Liang Guo, Cong Gao, Xiulai Chen, Jia Liu, Guipeng Hu, Liming Liu*. Recent advances in strategies for improvement of natural products production efficiency in Streptomyces[J]. Engineering Microbiology, 2022. accept Yanli Qi(齐艳利), Nan Xu, Zehong Li, Jiaping Wang, Xin Meng, Cong Gao, Jian Chen, Wei Chen, Xiulai Chen, Liming Liu*. Mediator engineering of Saccharomyces cerevisiae to improve multidimensional stress tolerance[J]. Applied and Environmental Microbiology, accept Hui Liu(刘晖), Pei Zhou, Mengya Qi, Liang Guo, Cong Gao, Guipeng Hu, Wei Song, Jing Wu, Xiulai Chen, Jian Chen, Wei Chen, Liming Liu*. Enhancing biofuels production by engineering the actin cytoskeleton in Saccharomyces cerevisiae[J]. Nature Communications, accept. Irene Komera, Cong Gao, Liang Guo, Guipeng Hu, Xiulai Chen, Liming Liu*.Bifunctional optogenetic switch for improving shikimic acid production in E. coli[J]. Biotechnology for Biofuels and Bioproducts, 2022, 15(1): 13. Wei Song(宋伟), Kai Zheng, Xin Xu, Cong Gao, Liang Guo, Jia Liu, Xiulai Chen, Liming Liu, Guipeng Hu, and Jing Wu*. Enzymatic production of ascorbic acid-2-Phosphate by engineered Pseudomonas aeruginosa acid phosphatase[J]. Journal of Agricultural and Food Chemistry, 2021, 69(47):14215-14221. Qiang Ding(丁强), Yadi Liu; Guipeng Hu; Liang Guo; Cong Gao; Xiulai Chen; Wei Chen; Jian Chen; Liming Liu*. Engineering Escherichia coli biofilm to increase contact surface for shikimate and L-malate production[J]. Bioresources and Bioprocessing, 2021, 8(1):118. Liang Guo(郭亮), Shuang Ding, Yadi Liu, Cong Gao, Guipeng Hu, Wei Song, Jia Liu, Xiulai Chen, Liming Liu*. Enhancing tryptophan production by balancing precursors in Escherichia coli[J]. Biotechnology and Bioengineering, 2021, 119(3): 983-993. Cong Gao(高聪), Wenxiu Tang, Liang Guo, Guipeng Hu, Jia Liu, Liming Liu, Xiulai Chen*. Improving succinate production by engineering oxygen‑dependent dynamic pathway regulation in Escherichia coli[J]. Systems Microbiology and Biomanufacturing, 2021, accept. Hui Liu (刘晖), Weijia Yuan, Pei Zhou, Guangjie Liang, Cong Gao, Liang Guo, Guipeng Hu, Wei Song, Jing Wu, Xiulai Chen, Liming Liu*. Engineering membrane asymmetry to increase medium-chain fatty acid tolerance in Saccharomyces cerevisiae[J]. Biotechnology and Bioengineering, 2021, 119(1): 277-286. Wenwen Diao(刁文文), Liang Guo, Qiang Ding, Cong Gao, Guipeng Hu, Xiulai Chen, Yang Li, Linpei Zhang, Wei Chen, Jian Chen, Liming Liu*. Reprogramming microbial populations using a programmed lysis system to improve chemical production[J]. Nature Communications, 2021, 12(1): 6886. Cong Gao(高聪), Jiaping Wang, Liang Guo, Guipeng Hu, Jia Liu, Wei Song, Liming Liu, Xiulai Chen*. Immobilization of microbial consortium for glutaric acid production from lysine[J]. ChemCatChem, 2021, 13(23): 5047-5055. Xin Xu (徐歆), Shengheng Yan, Xiaodong Hou, Wei Song, Lei Wang, Tianfu Wu, Mengya Qi, Jing Wu, Yijian Rao*, Binju Wang*, Liming Liu*. Local electric field modulated reactivity of Pseudomonas aeruginosa acid phosphatase for enhancing phosphorylation of L-ascorbic acid[J]. ACS Catalysis, 2021, 11(21), 13397-13407 Tian Tong(童天), Xiulai Chen, Guipeng Hu, Xiao-Ling Wang, Gao-Qiang Liu* and Liming Liu*. Engineering microbial metabolic energy homeostasis for improved bioproduction[J]. Biotechnology Advances, 2021, 53: 107841. Cong Gao(高聪), Liang Guo, Guipeng Hu, Jia Liu, Xiulai Chen, Xiaoxia Xia, Liming Liu*. Engineering a CRISPRi circuit for autonomous control of metabolic flux in Escherichia coli[J]. ACS Synthetic Biology, 2021, 10(10): 2661-2671.

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