近期论文
查看导师新发文章
(温馨提示:请注意重名现象,建议点开原文通过作者单位确认)
Zhu, H. J.; Zhang, B.; Wang, L.; Wang, W.; Liu, S. H.; Igarashi, Y.; Bashiri, G.; Tan, R. X.;* Ge, H. M.*, Redox Modifications in the Biosynthesis of Alchivemycin A Enable the Formation of Its Key Pharmacophore. J Am Chem Soc 2021, 143 (12), 4751-4757.
Wang, K. B.; Wang, W.; Zhang, B.; Wang, X.; Chen, Y.; Zhu, H. J.; Liang, Y.; Tan, R. X.;* Ge, H. M., A 6+4 -cycloaddition adduct is the biosynthetic intermediate in streptoseomycin biosynthesis. Nat Commun 2021, 12 (1), 2092.
Shi, J.; Xu, X.; Liu, P. Y.; Hu, Y. L.; Zhang, B.; Jiao, R. H.; Bashiri, G.; Tan, R. X.;* Ge, H. M.,* Discovery and biosynthesis of guanipiperazine from a NRPS-like pathway. Chem Sci 2021, 12 (8), 2925-2930.
Liu, S. H.; Wei, Y. Y.; Xing, Y. N.; Chen, Y.; Wang, W.; Wang, K. B.; Liang, Y.; Jiao, R. H.; Zhang, B.;* Ge, H. M.*, A BBE-like Oxidase, AsmF, Dictates the Formation of Naphthalenic Hydroxyl Groups in Ansaseomycin Biosynthesis. Org Lett 2021, 23(9), 3724-3728.
Li, W.; Wei, L.; Chen, D.-Y.; Wang, M.-J.; Sun, Y.; Jiao, F.-W.; Jiao, R.-H.; Tan, R.-X.;* Ge, H.-M.,* Study on the secondary metabolites of grasshopper-derived fungi Arthrinium sp. NF2410. Chinese Journal of Natural Medicines 2020, 18 (12), 957-960.
Xu, Z. F.; Bo, S. T.; Wang, M. J.; Shi, J.; Jiao, R. H.; Sun, Y.; Xu, Q.; Tan, R. X.; Ge, H.-M.,* Discovery and biosynthesis of bosamycins from Streptomyces sp. 120454. Chem Sci 2020,11 (34), 9237-9245.
Yang, C. L.; Zhang, B.; Xue, W. W.; Li, W.; Xu, Z. F.; Shi, J.; Shen, Y.; Jiao, R. H.; Tan, R. X.; Ge, H. M., Discovery, Biosynthesis, and Heterologous Production of Loonamycin, a Potent Anticancer Indolocarbazole Alkaloid. Org Lett 2020,22 (12), 4665-4669.
Dai, G. Z.; Han, W. B.; Mei, Y. N.; Xu, K.; Jiao, R. H.; Ge, H. M.; Tan, R. X., Pyridoxal-5 '-phosphate dependent bifunctional enzyme catalyzed biosynthesis of indolizidine alkaloids in fungi. Proceedings of the National Academy of Sciences of the United States of America 2020,117 (2), 1174-1180.
Fan, M.; Chen, J.; Gao, J.; Xue, W.; Wang, Y.; Li, W.; Zhou, L.; Li, X.; Jiang, C.; Sun, Y.; Wu, X.; Wu, X.; Ge, H.; Shen, Y.; Xu, Q., Triggering a switch from basal- to luminal-like breast cancer subtype by the small-molecule diptoindonesin G via induction of GABARAPL1. Cell Death & Disease 2020,11 (8).
Tan, Y.; Guo, Z.; Zhu, M.; Shi, J.; Li, W.; Jiao, R.; Tan, R.; Ge, H.*, Anti-inflammatory spirobisnaphthalene natural products from a plant-derived endophytic fungus Edenia gomezpompae. Chinese Chemical Letters 2020,31 (6), 1406-1409.
Xu, K.; Zhang, X.; Chen, J. W.; Shen, Y.; Jiang, N.; Tan, R. X.; Jiao, R. H.; Ge, H. M.*, Anti-inflammatory diterpenoids from an endophytic fungus Phomopsis sp. S12. Tetrahedron Lett 2019,60 (38).
Cheng, P.; Xu, K.; Chen, Y. C.; Wang, T. T.; Chen, Y.; Yang, C. L.; Ma, S. Y.; Liang, Y.; Ge, H. M.*; Jiao, R. H.*, Cytotoxic aromatic polyketides from an insect derived Streptomyces sp. NA4286. Tetrahedron Lett 2019,60 (26), 1706-1709.
Dai, G. Z.; Han, W. B.; Mei, Y. N.; Xu, K.; Jiao, R. H.; Ge, H. M.; Tan, R. X.*, Pyridoxal-5 '-phosphate dependent bifunctional enzyme catalyzed biosynthesis of indolizidine alkaloids in fungi. Proceedings of the National Academy of Sciences of the United States of America 2020,117 (2), 1174-1180.
Shi, J.; Xu, X.; Zhao, E. J.; Zhang, B.; Li, W.; Zhao, Y.; Jiao, R. H.*; Tan, R. X.; Ge, H. M.*, Genome Mining and Enzymatic Total Biosynthesis of Purincyclamide. Org Lett 2019,21 (17), 6825-6829.
Zhou, Z.-Z.; Zhu, H.-J.; Yang, C.-L.; Liu, Y.-J.; Jiang, N.; Xiao, Y.-S.; Shi, L.-Y.; Jiao, R.-H.; Ge, H.-M.; Tan, R.-X*., Dalestones A and B, two anti-inflammatory cyclopentenones from Daldinia eschscholzii with an edited strong promoter for the global regulator LaeA-like gene. Chinese Journal of Natural Medicines 2019,17 (5), 387-393.
Han, H.; Guo, Z.-K.; Zhang, B.; Zhang, M.; Shi, J.; Li, W.; Jiao, R.-H.; Tan, R.-X.; Ge, H.-M.*, Bioactive phenazines from an earwig-associated Streptomyces sp. Chinese Journal of Natural Medicines 2019,17 (6), 475-480.
Liu, S. H.; Wang, W.; Wang, K. B.; Zhang, B.; Li, W.; Shi, J.; Jiao, R. H.; Tan, R. X.; Ge, H. M., Heterologous Expression of a Cryptic Giant Type I PKS Gene Cluster Leads to the Production of Ansaseomycin. Org Lett 2019, 21 (10), 3785-3788.
Shi, J.; Liu, C. L.; Zhang, B.; Guo, W. J.; Zhu, J. P.; Chang, C. Y.; Zhao, E. J., Jiao, R. H.; Tan. R. X.; Ge, H. M.* Genome mining and biosynthesis of kitacinnamycins as a STING activator. Chem. Sci., 2019, 4839-4846.
Zhang, B.;† Wang, K. B.;† Wang, W.;† Wang, X.;† Liu, F.; Zhu, J.P.; Shi, J.; Li L. Y.; Han, H.; Xu, K.; Qiao, H. Y.; Zhang, X.; Jiao, R. H.; Houk, K. N.;* Liang, Y.;* Tan, R. X.;* Ge, H. M.* Enzyme-catalysed [6+4] cycloadditions in the biosynthesis of natural products. Nature2019, 568, 122-126.
Shi, J.; Zeng, Y. J.; Zhang, B.; Shao, F. L.; Chen, Y. C.; Xu, X.; Sun, Y.; Xu, Q.; Tan, R. X.*; Ge, H. M.* Comparative genome mining and heterologous expression of an orphan NRPS gene cluster direct the production of ashimides. Chem. Sci., 2019, 10, 3042-3048.