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个人简介

2016-2017 Managing Director of the Max-Planck-Institut für Kohlenforschung 2009-2011 Managing Director of the Max-Planck-Institut für Kohlenforschung since 1998 Director at the Max-Planck-Institut für Kohlenforschung and Professor at the Technical University of Dortmund 1993-1998 Group leader at the Max-Planck-Institut für Kohlenforschung and Lecturer at the University of Dortmund 1992 “Habilitation” in Organic Chemistry at the Technical University Graz, Austria 1990-1991 Postdoctoral fellow at the University of Geneva, Switzerland (W. Oppolzer) 1987 PhD at the Technical University Graz, Austria (H. Weidmann) 1962 born in Bruck/Mur (Austria)

研究领域

The research in the Department of Organometallic Chemistry is focused on the development and understanding of organometallic reagents and catalysts, as well as on their application to the synthesis of structurally complex targets of biological significance. Particular attention is paid to the development and validation of catalytic methods for C-C-bond formation. Long term projects of current interest concern alkene and alkyne metathesis, the development and use of pi-acids (platinum, gold etc.), iron catalysis and cross coupling in general. Moreover, the group is engaged in the development of novel donor ligands, including carbenes and compounds containing formally "zerovalent" carbon atoms. All methods are scrutinized by applications to the total synthesis and "diverted total synthesis" of natural products and pharmaceutically active compounds.

近期论文

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Buchsteiner, M., Martinez-Rodriguez, L., Jerabek, P., Pozo, I., Patzer, M., Nöthling, N., Lehmann, C. W., & Fürstner, A. (2020). Catalytic Asymmetric Fluorination of Copper Carbene Complexes: Preparative Advances and a Mechanistic Rationale. Chemistry – A European Journal, 26(11), 2509-2515. doi:10.1002/chem.202000081. Heinrich, M., Murphy, J. J., Ilg, M. K., Letort, A., Flasz, J. T., Philipps, P., & Fürstner, A. (2020). Chagosensine: A Riddle Wrapped in a Mystery Inside an Enigma. Journal of the American Chemical Society, 142(13), 6409-6422. doi:10.1021/jacs.0c01700. Fürstner, A., List, B., Ritter, T., Schüth, F., & Neese, F. (2020). Walter Thiel (1949–2019). Angewandte Chemie International Edition, 59(4), 1382-1383. doi:10.1002/anie.201915463. Hillenbrand, J., Leutzsch, M., Yiannakas, E., Gordon, C. P., Wille, C., Nöthling, N., Copéret, C., & Fürstner, A. (2020). “Canopy Catalysts” for Alkyne Metathesis: Molybdenum Alkylidyne Complexes with a Tripodal Ligand Framework. Journal of the American Chemical Society, 142(25), 11279-11294. doi:10.1021/jacs.0c04742. Meng, Z., & Fürstner, A. (2020). Total Synthesis Provides Strong Evidence: Xestocyclamine A is the Enantiomer of Ingenamine. Journal of the American Chemical Society, 142(27), 11703-11708. doi:10.1021/jacs.0c05347. Karier, P., Ungeheuer, F., Ahlers, A., Anderl, F., Wille, C., & Fürstner, A. (2019). Metathesis at an Implausible Site: A Formal Total Synthesis of Rhizoxin D. Angewandte Chemie International Edition, 58(1), 248-253. doi:10.1002/anie.201812096. Mata, G., Wölfl, B., & Fürstner, A. (2019). Synthesis and Molecular Editing of Callyspongiolide, Part 1: The Alkyne Metathesis / trans‐Reduction Strategy. Chemistry – A European Journal, 25(1), 246-254. doi:10.1002/chem.201804987. Meng, Z., & Fürstner, A. (2019). Total Synthesis of (−)-Sinulariadiolide. A Transannular Approach. Journal of the American Chemical Society, 141(2), 805-809. doi:10.1021/jacs.8b12185. Wölfl, B., Mata, G., & Fürstner, A. (2019). Total Synthesis of Callyspongiolide, Part 2: The Ynoate Metathesis / cis‐Reduction Strategy. Chemistry – A European Journal, 25(1), 255-259. doi:10.1002/chem.201804988. Fürstner, A. (2019). trans-Hydrogenation, gem-Hydrogenation, and trans-Hydrometalation of Alkynes: An Interim Report on an Unorthodox Reactivity Paradigm. Journal of the American Chemical Society, 141(1), 11-24. doi:10.1021/jacs.8b09782. Collins, L. R., Auris, S., Goddard, R., & Fürstner, A. (2019). Chiral Heterobimetallic Bismuth‐Rhodium Paddlewheel Catalysts: A Conceptually New Approach to Asymmetric Cyclopropanation. Angewandte Chemie International Edition, 58(11), 3557-3561. doi:10.1002/anie.201900265. Tskhovrebov, A. G., Lingnau, J., & Fürstner, A. (2019). Gold Difluorocarbenoid Complexes: Spectroscopic and Chemical Profiling. Angewandte Chemie International Edition, 58(26), 8834-8838. doi:10.1002/anie.201903957. Jin, H., & Fürstner, A. (2019). Regioselective trans-Carboboration of Propargyl Alcohols. Organic Letters, 21(9), 3446-3450. doi:10.1021/acs.orglett.9b01225. Peil, S., Guthertz, A., Biberger, T., & Fürstner, A. (2019). Hydrogenative Cyclopropanation and Hydrogenative Metathesis. Angewandte Chemie International Edition, 58(26), 8851-8856. doi:10.1002/anie.201904256. Fürstner, A. (2019). Discussion Addendum for: 4-Nonylbenzoic Acid. In J. L. Wood (Ed.), Organic Syntheses (pp. 1-15). Hoboken: John Wiley & Sons. doi:10.15227/orgsyn.096.0001. Biberger, T., Gordon, C., Leutzsch, M., Peil, S., Guthertz, A., Copéret, C., & Fürstner, A. (2019). Alkyne gem‐Hydrogenation: Formation of Pianostool Ruthenium Carbene Complexes and Analysis of Their Chemical Character. Angewandte Chemie International Edition, 58(26), 8845-8850. doi:10.1002/anie.201904255. Longobardi, L. E., & Fürstner, A. (2019). trans‐Hydroboration of Propargyl Alcohol Derivatives and Related Substrates. Chemistry – A European Journal, 25(43), 10063-10068. doi:10.1002/chem.201902228. Hillenbrand, J., Leutzsch, M., & Fürstner, A. (2019). Molybdenum Alkylidyne Complexes with Tripodal Silanolate Ligands: The Next Generation of Alkyne Metathesis Catalysts. Angewandte Chemie, International Edition, 58(44), 15690-15696. doi:10.1002/anie.201908571. Huang, L., Gu, Y., & Fürstner, A. (2019). Iron-Catalyzed Reactions of 2‐Pyridone Derivatives: 1,6‐Addition and Formal Ring Opening/Cross Coupling. Chemistry – An Asian Journal, 14(22), 4017-4023. doi:10.1002/asia.201900865. Peil, S., & Fürstner, A. (2019). Mechanistic Divergence in the Hydrogenative Synthesis of Furans and Butenolides: Ruthenium Carbenes Formed by gem‐Hydrogenation or through Carbophilic Activation of Alkynes. Angewandte Chemie, International Edition, 58(51), 18476-18481. doi:10.1002/anie.201912161.

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