马骁驰 - 大连医科大学

个人简介

马骁驰教授，博士生导师，国家优青，辽宁省特聘教授，百人层次。在中药化学与代谢以及中西医结合研究领域，以第一或通讯作者发表 SCI 论文 55 篇,其中影响因子(IF)>10, 2篇; IF>5 (18篇); IF>4 (6篇); IF>3 (20篇), 包括J Pineal Res., Catal. Sci. Technol.; Sci. Rep.; Biochem. Pharmacol.; British J. Pharm.; Chem. Commun.; Pharm. Res., J. Lipid Res.; Mol. Cancer; Drug Metab. Dispos.; J. Nat. Prod.等本领域权威期刊，总引用 1000 余次，两篇入选 ESI 高被引论文。主持国家自然科学基金项目 5 项 (优秀青年基金 1项，面上项目 3项，青年基金 1项), 国家重点实验室课题 1项，主持完成省市级课题 10项。主持横向课题近 10 项。入选国家自然科学基金优青、辽宁省特聘教授、省百人层次、高校优秀人才计划; 获教育部科技进步二等奖1项; 辽宁省科技进步二等奖2项，辽宁省优秀学术成果二、三等奖各 1 项, 辽宁省青年科技奖，大连市杰出青年, 大连市优秀专家。第一发明人申请专利6 项，授权2项。编写教材/著作11部 (副主编3部)。担任国家自然基金二审专家、国家自然科学基金、教育部博士后基金通讯评审专家；中科院“药物研究 ADME 技术”培训专家；世界中医药联合会-中药分析、中药化学、中药鉴定委员会理事；担任J. Chromatogr. A, Oncotarget, RSC Adv., J. Chromatogr. B, Toxicol. Appl. Pharm., Carbonhyd. Polym, Food Chem. Artificial Cells, Nanomedicine and Biotechnology等期刊审稿人。

研究领域

1. 中药及其复方的体内药效物质与作用机制研究 2. 代谢靶点的表征与调控 3. 中药代谢与合理用药

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Xiangge Tian, Sicheng Liang, Chao Wang, Baojian Wu, Guangbo Ge, Sa Deng, Kexin Liu, Ling Yang and Xiaochi Ma*. Regioselective Glucuronidation of Andrographolide and Its Major Derivatives: Metabolite Identification, Isozyme Contribution, and Species Differences. The AAPS Journal. 2015, 17(1), 156-166 (SCI, 3.91) Zhenlong Yu, Wei Guo, Xiaochi Ma*, Baojing Zhang, Peipei Dong, Lin Huang, Xiuli Wang, Chao Wang, Xiaokui Huo, Wendan Yu, Canhui Yi, Yao Xiao, Wenjing Yang, Yu Qin, Yuhui Yuan, Songshu Meng, Quentin Liu, Wuguo Deng*. Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKbeta/NF-kappaB signaling pathway in lung cancer cells. Molecular Cancer. 2014, 13: 203. (SCI, 5.41) Xia Lv, Dan Liu, Jie Hou, Peipei Dong, Libin Zhan, Li Wang, Sa Deng, Changyuan Wang, Jihou Yao, Xiaohong Shu, Kexin Liu, Xiaochi Ma*. Biotransformation of imperatorin by Penicillium janthinellum. Anti-osteoporosis activities of its metabolites. Food Chemistry. 138 (2013) 2260–2266. (SCI, 3.4) Yan Sun, Dan Liu, RongGang Xi, Xiaobo Wang, Yan Wang, Jie Hou, Baojing Zhang, Changyuan Wang, Kexin Liu, Xiaochi Ma*. Microbial transformation of acetyl-11-keto-β-boswellic acid and their inhibitory activity on LPS-induced NO production. Bioorg Med Chem Lett. 2013, 23(5), 1338-42. (SCI, 2.34) X. Lv, C.-Y. Wang, J. Hou, B.-J. Zhang, S. Deng, Y. Tian, S.-S. Huang, H.-L. Zhang, X.-H. Shu, Y.-H. Zhen, K.-X. Liu, J.-H. Yao, and Xiaochi Ma*. Isolation and identification of metabolites of osthole in rats. Xenobiotica. 2012, 42(11), 1120-7. (SCI, 2.8) Sa Deng, Bao Jing Zhang, Chang Yuan Wang, Yan Tian, Ji Hong Yao, Lei An, Shan Shan Huang, Jin Yong Peng, Ke Xin Liu, Xiaochi Ma*. Microbial transformation of deoxyandrographolide and their inhibitory activity on LPS-induced NO production in RAW 264.7 macrophages. Bioorg Med Chem Lett. 2012, 22(4), 1615-8. (SCI, 2.7) Xiao-Chi Ma, Jing Ning, Guang-Bo Ge, Si-Cheng Liang, Xiu-Li Wang, Bao-Jing Zhang, Shan-Shan Huang, Jing-Kui Li, and Ling Yang*. Comparative Metabolism of Cinobufagin in Liver Microsomes from Mouse, Rat, Dog, Pig, Monkey and Human. Drug Metabolism and Disposition. 2011. 39(4): 675-682 (SCI, 3.73) J. Ning T.-H. Wu, Y. Tian, C.-Y. Wang, G. Tian, B.-J. Zhang, K.-X. Liu, and Xiaochi Ma*. Identification of cinobufagin metabolites in the bile of rats. Xenobiotica. 2010, 40(1), 48-54. (SCI, 2.8) Jingkui Li, Xiaochi Ma*, Fengyun Li, Jingkui Wang, Huirong Chen, Gang Wang, Xia Lv, Changkai Sun, Jingming Jia. Preparative separation and purification of bufadienolides from Chinese traditional medicine of ChanSu using high-speed counter-current chromatography. J Sep Sci. 2010, 33(9), 1325-30. (SCI, 2.63) Feng-Yun Li, Zhan-Ping Gou, Xiaochi Ma*, Yan Tian, Ge Tian, Chang-Yuan Wang, Dong-Hai Su, Ke Xin Liu, Xiu-Lan Xin*. Preparative Isolation and Purification of Two Phenylpropanoids from Daphne giraldii Nitsche by HSCCC. Chromatographia. 2010, 71, 481-485. (SCI, 1.1)