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个人简介

1963年4月出生于浙江黄岩。1985年毕业于中国药科大学,获学士学位;1988年至1989年在日本富山医科药科大学和汉药研究所学习;1990年7月在中国药科大学获得博士学位;1990年9月进入北京医科大学药学院进行博士后研究,1992年12月博士后出站后留校工作至今。1993年被聘为副教授,1997年被聘为教授,1999年被评为博士生导师

研究领域

(1)中药活性成分与新药研究 (2)天然活性成分结构改造与构效关系研究 (3)中药质量分析

近期论文

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Cunqin Jia, Haiming Shi, Wei Jin, Ke Zhang, Yong Jiang, Mingbo Zhao, and Pengfei Tu*. Metabolism of Echinacoside, a Good Antioxidant, in Rats: Isolation and Identification of Its Biliary Metabolites. Drug Metabolism and Disposition, 2009, 37:431–438 Zheng-Ren Xu, Xing-Yun Chai, Chang-Cai Bai, Hong-Yan Ren, Ya-Nan Lu, Hai-Ming Shi, Peng-Fei Tu*. Xylocosides A-G, phenolic Glucosides from the Stems of Xylosma controversum, Helvetica Chimica Acta, 2008(91): 1346-1354 Xing Yun Chai, Yue Lin Song, Zheng Ren Xu, Hai Ming Shi, Chang Cai Bai, Dan Bi, Jing Wen, Fei Fei Li, and Peng Fei Tu*. Itosides J-N from Itoa orientalis and structure - Anti-COX-2 activity relationship of phenolic glycosides , Journal of Natural Products, 2008( 5) : 814-819 Xing-Yun Chai, Chang-Cai Bai, Hai-Ming Shi, Zheng-Ren Xu, Hong-Yan Ren, Fei-Fei Li,Ya-Nan Lu, Yue-Lin Song, Peng-Fei Tu * . Six insecticidal isoryanodane diterpenoids from the bark and twigs of Itoa Orientalis , Tetrahedron , 2008 (64): 5743–5747 Lei Liu, An-Liang Li, Ming-Bo Zhao, Peng-Fei Tu. Tetralones and Flavonoids from Pyrola calliantha. Chemistry & Biodiversity. 2007, 4:2932-2937 Wei Jin, Ying-Feng Wang, Ri-Li Ge, Hai-Ming Shi, Cun-Qin Jia and Peng-Fei Tu*. Simultaneous analysis of multiple bioactive contituentes in Rheum tanguticum Maxim. Ex Balf. By high-performance liquid chromatography coupled to tandem mass spectrometry. Rapid Communications in Mass Spectrometry, 2007, 21:2351-2360 Guang-bo Xie, Lian-di Lei, Peng-fei Tu*.Complete assignments of 1H and 13C NMR spectroscopic data for two new triterpenoid saponins from Ilex pernyi, Magnetic Resonance in Chemistry, 2007, 45:997-1000 Shepo Shi, Dan Jiang, Mingbo Zhao, Pengfei Tu*. Preparative isolation and purification of triterpene saponins from Clematis mandshurica by high-speed counter-current chromatography coupled with evaporative light scattering detection, Journal of Chromatography B. 2007, 852:679-683 Y. Jiang , P. Li , S. P. Li , Y.T.Wang , P. F. Tu*. Optimization of pressurized liquid extraction of five major flavanoids from Lysimachina clethroide . Journal of Pharmaceutical and Biomedical Analysis , 2007, 43:341-345 Cunqin Jia, Haiming Shi, Xiangmei Wu, Yinzeng Li, Jingjing Chen, Pengfei Tu*. Determination of echinacoside in rat serum by reversed-phase high-performance liquid chromatography with ultraviolet detection and its application to pharmacokinetics and bioavailability. Journal of Chromatography B . 2006, 844: 308-313 Jiang D, Gao QP, Shi SP, Tu PF*. Triterpenoid saponins from the fruits of Akebiae quinata. Chemical & Pharmaceutical Bulletin . 2006, 54 (5): 595-597 Wu XM, Dai H, Huang LX, Tu Pengfei*. A fructan, from radix ophiopogonis, stimulates the proliferation of cultured lymphocytes: Structural and functional analyses. Journal of Natural Products. 2006, 69 (9): 1257-1260 Shi SP, Jiang D, Dong CX, Pengfei Tu* . Triterpene Saponins from Clematis mandshurica. Journal of Natural Products. 2006, 69 (11): 1591-1595 Hai-Ming Shi, Jing Wen, Cun-Qin Jia, Wei Jin, Xiu-Feng Zhang, Zhi-Rong Yao, Peng-Fei Tu *. Two new phenolic glycosides from the barks of Hydnocarpus annamensis and their Anti-inflammatory and Anti-Oxidation Activities, Planta Medica, 2006, 72 (10) :948-950 Wei Jin, Ri-Li Ge, Quan-Jia Wei, Tian-You Bao, Hai-Ming Shi, Peng-Fei Tu*. Developmeng of high-performance liquid chromatographic fingerprint for the quality control of Rheum tanguticum Maxin. ex Balf. Journal of chromatography A , 2006, 1132:320-324 Pengfei Tu*, Zhihong Song, Haiming Shi, Yong Jiang, Yuying Zhao. Arylethyl ( ="Phenylethanoid" ) Glycosides and Oligosaccharide from the Stem of Cistanche tubulosa , Helvetica Chimica Acta, 2006, 89 : 927~935 Y. Jiang, S. P. Li, H. T. Chang, Y. T. Wang, P. F. Tu*, Pressurized liquid extraction followed by high-performance liquid chromatography for determination of seven active compounds in Cortex Dictamni, Journal of Chromatography A , 2006 , 1108: 268-272 Xiang Mei Wu, Xiao Ming Gao, Karl W.K. Tsim and Peng Fei Tu*, An arabinogalactan isolated from the stems of Cistanche deserticola induces the proliferation of cultured lymphocytes , International Journal of Biological Macromolecules, 2005, 37:278-282 Jun Li , Yong Jiang, and Pengfei Tu*, Xanthone O-Glycosides and Benzophenone O-Glycosides from the Roots of polygala tricornis, Journal of Natural Products, 2005, 68:1802-1804 Yong Jiang, Wei Zhang , Pengfei Tu*, Xiaojie Xu. Xanthone Glycosides from Polygala tenuifolia and Their Conformational Analyses , Journal of Natural Products, 2005, 68: 875-879

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