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Analytical Chemistry/Inorganic Chemistry/Organic Chemistry/Physical Chemistry/Biological Chemistry/Chemical Education/Computational/Theoretical Chemistry/Environmental/Atmospheric Chemistry/Materials Chemistry and Nanoscience

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Qian, K. and Zheng, Y. G. (2014) Labeling: Palladium brings proteins to life. Nature Chem Biol. 10, 328-330. Yan, L., Yan, C., Su, H., Qian, K., Wofford, S., Lee, W., Zhao, X., Ho, M., Ivanov, I. and Zheng, Y. G. (2014) Diamidine Compounds for Selective Inhibition of Protein Arginine Methyltransferases. J Med Chem, 57, 2611-2622. Yang, C., Ngo, L., Zheng, Y. G. (2014) Rational Design of Substrate-Based Multivalent Inhibitors of Histone Acetyltransferases. ChemMedChem. 9, 537-541. Zhang, R., Li, X., Liang, Z., Zhu, K., Lu, J., Kong, X., Ouyang, S., Li, L., Zheng, Y. G. and Luo, C. (2013) Theoretical insights into catalytic mechanism of protein arginine methyltransferase 1. PLoS One. 8, e72424. Xu, J., Liu, J., Wang, A. H., Oses-Prieto, J., Makhijani, K., Pei, M., Kastuno, Y., Leilei, Y., Zheng, Y. G., Burlingame, A., Brückner, K., Derynck, R. (2013) Arginine methylation initiates BMP-induced Smad signaling. Mol Cell. 51, 5-19. Yang, C., Mi, J., Feng, Y., Ngo, L., Gao, T., Yan, L. and Zheng, Y. G. (2013) Labeling lysine acetyltransferase substrates with engineered enzymes and functionalized cofactor surrogates. J Am Chem Soc. 135, 7791-7794. Gao, T. Yang, C., and Zheng, Y. G. (2013) Comparative studies of thiol-sensitive fluorogenic probes for HAT inhibitor screening. Anal Chem Biochem. 405, 1361-1371. Yang, C., Wu, J., Sinha, S., Neveu, J. M. and Zheng, Y. G. (2012) Autoacetylation of the MYST Lysine Acetyltransferase MOF. J Biol Chem. 287, 34917-34926. Wang, J., Chen, L., Sinha, S. H., Liangb, Z., Cai, H., Muniyanf, S., Chou, Y., Yang, C., Li, K., Lin, M., Jiang, H., Zheng, Y. G. and Luo, C. (2012) Pharmacophore-Based Virtual Screening and Biological Evaluation of Small Molecule Inhibitors for Histone Arginine Methyltransferases. J Med Chem. 55, 7978–7987. Sinha, S. H., Owens, E., Feng, Y., Yang, Y., Xie, Y., Tu, Y., Henary, M.* and Zheng, Y. G. (2012) Synthesis and evaluation of carbocyanine dyes as PRMT inhibitors and imaging agents. Eur J Med Chem. 54, 647-659. Ni, T., Laughlin, S., Wang, Y., Feng, Y., Zheng, Y. G. and Wang, B. (2012) Probing the general time scale question of boronic acid binding with sugars in aqueous solution at physiological pH. Bioorgan Med Chem. 20, 2957-2961. Yang, C. Wu, J. and Zheng, Y. G. (2012) Function of the Active Site Lysine Autoacetylation in Tip60 in Catalysis. PLoS ONE. 7, e32886. Gao, T. and Zheng, Y. G. (2012) The fluorescence-based acetylation assay using thiol-sensitive probes. Methods Mol Biol. 981, 229-38. Ghizzoni, M., Wu, J., Gao T., Haisma, H. J., Dekker, F. J. and Zheng, Y. G. (2012) 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. Eur J Med Chem. 47, 337–344. Yuan, H., Rossetto, D., Mellet, H., Dang, W., Srinivasan, M. Johnson, J., Hodawadekar, S., Ding, E. C., Speicher, K., Abshiru, N., Perry, R., Yang, C., Wu, J., Zheng, Y. G., Speicher, D. W., Thibault, P., Verreault, A., Johnson, F. B., Berger, S. L., Sternglanz, R., McMahon, S. B., Jacques Côté, J., Marmorstein, R. (2012) MYST Protein Acetyltransferase Activity Requires Active Site Lysine Autoacetylation. EMBO J. 31, 58-70. Wu, J., Xie, N. and Zheng, Y. G. (2012) Scintillation Proximity Assay of arginine methylation. J Biomol Screen. 17, 237-244. Li, K., Luo, C., Wang, D. and Zheng, Y. G. (2012) Chemical and biochemical approaches in the study of histone methylation and demethylation. Med Res Rev. 32, 815-867 Feng, Y., Xie, N., Jin, M., Stahley, M. R., Stivers, J. T. and Zheng, Y. G. (2011) A transient kinetic analysis of PRMT1 catalysis. Biochemistry. 50, 7033–7044 Wu, J., Wang, J., Li, M., Yang, Y., Wang, B. and Zheng, Y. G. (2011) Small molecule inhibitors of histone acetyltransferase Tip60. Bioorg Chem. 39, 53-58 Feng, Y., Wang, J., Asher, S., Hoang, L., Guardiani, C., Ivanov, I. and Zheng, Y. G. (2011) Histone H4 Acetylation Differentially Modulates Arginine Methylation by an In Cis Mechanism. J Biol Chem. 286, 20323-20334 Wu, J. and Zheng, Y. G. (2010) Synthesis of H4 pantetheine adducts for histone acetyltransferase inhibition. Heterocycl Commun. 16, 231-234 Feng, Y., Li, M., Wang, B. and Zheng, Y. G. (2010) Discovery and Mechanism of a Type of new PRMT inhibitors. J Med Chem. 53, 6028-6039

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