贾彦兴 - 北京大学

个人简介

学习经历 1993-1997 理学学士，兰州大学化学系应用化学专业 1997-2002 理学博士，兰州大学化学系有机化学专业（导师：涂永强院士） 2002-2007 博士后，法国国家科学研究中心，天然产物化学研究所（导师：祝介平）任职 2007.8 副教授，北京大学，课题组长 2011.8 教授，北京大学

研究领域

1.具有重要生物活性天然产物的全合成及仿生合成 2.药物合成及构效关系研究 3.有机合成新方法、新策略的研究 4.基于天然产物小分子探针的发现

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Total Synthesis of (-)-Glaucocalyxin A, Jiuzhou Guo, Bo Li, Weihao Ma, Mallesham Pitchakuntla, Yanxing Jia, Angew. Chem. Int. Ed. 2020, 59, 1 – 5 Y. Wang, K. Liu, Z. Yu, Y. Jia. Type-II Pauson-Khand reaction of 1,8-enyne in the attempt of building 7/5 ring of (-)-caribenol A and DFT understanding. Tetrahedron Lett. 2019, Shibin Shi, Kuo Yuan, Yanxing Jia. Seven-step total synthesis of α-cyclopiazonic acid. Chin. Chem. Lett. 2019, Xiwu Zhang Xinxian Cai Bin Huang Lei Guo Zhongrun Gao Prof. Yanxing Jia. Enantioselective Total Syntheses of Pallambins A–D. Angew. Chem. Int. Ed. 2019, 58, 13380 –13384 Weihao Ma, Zhi Huang, Yanxing Jia*. Improved synthesis of key intermediate of grayanotoxin III[J]. Chin. J. Org. Chem., 2019, 28(6): 402-407. H. Liu, L. Chen, K. Yuan, Y. Jia, A Ten‐Step Total Synthesis of Speradine C, Angew. Chem. Int. Ed. 2019, 58, 6362. L. Li, K. Yuan, Q. Jia, Y. Jia, Eight‐Step Total Synthesis of Phalarine by Bioinspired Oxidative Coupling of Indole and Phenol, Angew. Chem. Int. Ed. 2019, 58, 6074. Zhuang Chen, Mallesham Pitchakuntla and Yanxing Jia. Synthetic approaches to natural products containing 2,3-dihydrobenzofuran skeleton. Nat. Prod. Rep., 2019, 36, 666–690 Yuan Kuo, Jia Yanxing. Recent Progress in the Synthesis of 3,4-Fused Indole Alkaloids[J]. Chin. J. Org. Chem., 2018, 38(9): 2386-2399. Lei Li, Zhuang Chen, Xiwu Zhang, and Yanxing Jia. Divergent Strategy in Natural Product Total Synthesis. Chemical Reviews, 2018, 118 (7), pp 3752–3832 Lv, J.; Wang, B.; Yuan, K.; Wang, Y.; Jia, Y., Regioselective Direct C‑4 Functionalization of Indole: Total Syntheses of (−)-Agroclavine and (−)-Elymoclavine. Org. Lett. 2017, Ma, Y; Jia, Y. J. Synthetic study toward the total synthesis of fumigaclavines A–D. Chin. Pharm. Sci. 2017, 26, (7), 496–503. Liu, H.; Zhang, X.; Shan, D.; Pitchakuntla, M.; Ma, Y.; Jia, Y. Org. Lett. 2017, 19, 3323−3326. Link49. Liu, H.; Zhang, X.; Shan, D.; Pitchakuntla, M.; Ma, Y.; Jia, Y. Org. Lett. 2017, 19, 3323−3326. Shi, L.; Li, L.; Wang, J.; Huang, B.; Zeng, K.; Jin, H. Zhang, Q.; Jia, Y. Total synthesis of natural spiro-trisindole enantiomers similisines A, B and their stereoisomers. Tetrahedron Lett. 2017, 58(20), 1934-1938. Li, L.; Aibibula, P.; Jia, Q.; Jia, Y., Total Syntheses of Naucleamides A−C and E, Geissoschizine, Geissoschizol, (E)‑Isositsirikine, and 16-epi-(E)‑Isositsirikine. Org. 2017, 19, (10), 2642−2645. Liu, H.; Jia, Y., Ergot alkaloids: synthetic approaches to lysergic acid and clavine alkaloids. Nat. Prod. Rep. 2017, 34, 411-432. Huang, Z.; Lv, J.; Jia, Y., A Simple and Efficient Synthesis of Secondary Alkylamines from Nitroalkanes. ChemistrySelect 2016, 1, (18), 5892–5894. Tao, P.; Jia, Y., C–H bond activation in the total syntheses of natural products. Sci China Chem. 2016, 59, (9), 1109-1125. Tao, P.; Chen, Z.; Jia, Y., A concise gram-scale synthesis of ht-13-A via a rhodium-catalyzed intramolecular C–H activation reaction. Chem. Commun. 2016, 52, (75), 11300--1130 Aibibula, P.; Huang, Z.; Jia, Y., Asymmetric total synthesis of 3-epi-naucleamide A. J. Chin. Pharm. Sci. 2016, 25, (1), 30-36. Zhang, X.; Liu, H.; Jia, Y., A palladium-catalyzed intramolecular carbonylative annulation reaction for the synthesis of 4,5-fused tricyclic 2-quinolones. Chem. Commun. 2016, 52, (49), 7665-7667. Huang, B.; Zhang, F.; Yu, G.; Song, Y.; Wang, X.; Wang, M.; Gong, Z.; Su, R.; Jia, Y. J. Med. Chem., 2016, 59 (8), pp 3953–3963 Chen, Z.; Zhou, S.; Jia, Y., Formal Synthesis of (+)-Kopsihainanine A and Synthetic Study toward (+)-Limaspermidine. The Journal of Organic Chemistry 2015, 80, (24), 12545-12551. Zhang, F.; Guo, L.; Hu, W.; Jia, Y., Total synthesis of (−)-decursivine and analogues via cascade sequence. Tetrahedron 2015, 71, (22), 3756-3762. Huang, B.; Guo, L.; Jia, Y., Protecting-Group-Free Enantioselective Synthesis of (−)-Pallavicinin and (+)-Neopallavicinin. Angewandte Chemie International Edition 2015, 54, (46), 13599-13603. Li, L.; Yang, Q.; Wang, Y.; Jia, Y., Catalytic Asymmetric Total Synthesis of (−)-Galanthamine and (−)-Lycoramine. Angewandte Chemie International Edition 2015, 54, (21), 6255-6259. Guo, Y.; Liu, Q.; Jia, Y.,Concise synthesis of the tricyclic skeleton of crotobarin and crotogoudin via a gold-catalyzed cycloisomerization reaction. Chem. Commun. 2015, 51, (5), 889-891. Zhang, F.; Wang, B.; Prasad, P.; Capon, R. J.; Jia, Y., Asymmetric Total Synthesis of (+)-Dragmacidin D Reveals Unexpected Stereocomplexity.Organic Letters 2015, 17, (6), 1529-1532. Guo, L.; Zhang, F.; Hu, W.; Li, L.; Jia, Y. Chemical Communications 2014, 50, 3299. Link33. Guo, L.; Zhang, F.; Hu, W.; Li, L.; Jia, Y. Chemical Communications 2014, 50, 3299. Tao, P.; Liang, J.; Jia, Y., Total Synthesis of Dictyodendrins B and E, and Formal Synthesis of Dictyodendrin C. European Journal of Organic Chemistry 2014, 2014, (26), 5735-5748. Tao, P.; Jia, Y., Rhodium-catalyzed intramolecular annulation via C–H activation leading to fused tricyclic indole scaffolds. Chemical Communications 2014, 50, (55), 7367. Zhou, S.; Jia, Y., Total Synthesis of (−)-Goniomitine. Organic Letters 2014, 16, (12), 3416-3418. Link30. Zhou, S.; Jia, Y., Total Synthesis of (−)-Goniomitine. Organic Letters 2014, 16, (12), 3416-3418. Gao, Y.; Shan, D.; Jia, Y., Intramolecular Larock indole synthesis for the preparation of tricyclic indoles and its application in the synthesis of tetrahydropyrroloquinoline and fargesine. Tetrahedron 2014, 70, (34), 5136-5141. Li, L.; Hu, W.; Jia, Y., Synthetic studies of cyclic peptides stephanotic acid methyl ester, celogentin C, and moroidin. Tetrahedron 2014, 70, (42), 7753-7762. Bin Wang, H. Q. F. Z., Synthesis of the cycloheptannelated indole fragment of dragmacidin E. Tetrahedron Letters 2014, 55, (9), 1561-1563. Shan, D.; Gao, Y.; Jia, Y., Intramolecular Larock Indole Synthesis: Preparation of 3,4-Fused Tricyclic Indoles and Total Synthesis of Fargesine. Angewandte Chemie International Edition 2013, 52, (18), 4902-4905. Total Synthesis of (+)- and (−)-Decursivine and (±)-Serotobenine through a Cascade Witkop Photocyclization/Elimination/Addition Sequence: Scope and Mechanistic Insights. Chemistry - A European Journal 2013, 19, (9), 3139-3147. Liang, J.; Hu, W.; Tao, P.; Jia, Y., Total Synthesis of Dictyodendrins B and E. The Journal of Organic Chemistry 2013, 78, (11), 5810-5815. Zhang, Y.; Liu, Q.; Wang, C.; Jia, Y., Total Synthesis of Rugulovasine A. Organic Letters 2013, 15, (14), 3662-3665. Liu, Q.; Li, Q.; Ma, Y.; Jia, Y., Direct Olefination at the C-4 Position of Tryptophan via C–H Activation: Application to Biomimetic Synthesis of Clavicipitic Acid. Organic Letters 2013, 15, (17), 4528-4531.