Seeberger, Peter H. - Max Planck Institute of Colloids and Interfaces

个人简介

Peter H. Seeberger received his Vordiplom in 1989 from the Universität Erlangen-Nürnberg, where he studied chemistry as a Bavarian government fellow. In 1990 he moved as a Fulbright scholar to the University of Colorado where he earned his Ph.D. in biochemistry under the guidance of Marvin H. Caruthers in 1995. After a postdoctoral fellowship with Samuel J. Danishefsky at the Sloan-Kettering Institute for Cancer Research in New York City he became Assistant Professor at the Massachusetts Institute of Technology in January 1998 and was promoted to Firmenich Associate Professor of Chemistry with tenure in 2002. From June 2003 until January 2009 held the position of Professor for Organic Chemistry at the Swiss Federal Institute of Technology (ETH) in Zurich, Switzerland where he served as chair of the laboratory in 2008. In 2009 he assumed positions as Director at the Max-Planck Institute for Colloids and Surfaces in Potsdam and Professor at the Free University of Berlin. Since 2003 he serves as an Affiliate Professor at the Burnham Institute in La Jolla, CA. Peter H. Seeberger is the Editor of the Journal of Carbohydrate Chemistry and serves on the editorial advisory boards of eleven other journals. He is a founding member of the board of the Tesfa-Ilg "Hope for Africa" Foundation that aims at improving health care in Ethiopia in particular by providing access to malaria vaccines and HIV treatments. He is a consultant and serves on the scientific advisory board of several companies. In 2006 he served as president of the Swiss Academy of Natural Sciences. The research in professor Seeberger’s laboratory has resulted in two spin-off company: Ancora Pharmaceuticals (founded in 2002, Medford, USA) that is currently developing a promising malaria vaccine candidate in late preclinical trials as well as several other therapeutics based on carbohydrates and i2chem that is commercializing microreactors for chemical applications.

研究领域

Automated Glycan Assembly Biomolecular Systems Glycobiology and Vaccine Development Glycobiology of infections diseases Glycosaminoglycans Synthetic Vaccines

近期论文

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Fittolani, G.; Seeberger, P. H.; Delbianco, M.: Helical polysaccharides. Peptide Science (accepted) Le Mai Hoang, K.; Pardo-Vargas, A.; Zhu, Y.; Yu, Y.; Loria, M.; Delbianco, M.; Seeberger, P. H.: Traceless photolabile linker expedites chemical synthesis of complex oligosaccharides by automated glycan assembly. Journal of the American Chemical Society (2019) Gim, S.; Zhu, Y.; Seeberger, P. H.; Delbianco, M.: Carbohydrate‐based nanomaterials for biomedical applications. Wiley interdisciplinary reviews: nanomedicine and nanonbiotechnology (2019) Pieber, B.; Malik, J.; Cavedon, C.; Gisbertz, S.; Savateev, A.; Cruz, D.; Heil, T.; Zhang, G.; Seeberger, P. H.: Semi‐heterogeneous dual nickel/photo‐catalysis using carbon nitrides: esterification of carboxylic acids with aryl halides. Angewandte Chemie International Edition (2019) Chatterjee, S.; Moon, S.-Y.; Rowlands, A.; Chin, F.; Seeberger, P. H.; Merbouh, N.; Gilmore, K.: Click, Zoom, Explore: Interactive 3D (i-3D) Figures in Standard Manuscript PDFs. ChemRxiv (2019) Geißner, A.; Reinhardt, A.; Rademacher, C.; Johannssen, T.; Monteiro, J.; Lepenies, B.; Thépaut, M.; Fieschi, F.; Mrázková, J.; Wimmerova, M. et al.: Microbe-focused glycan array screening platform. Proceedings of the National Academy of Sciences of the United States of America 116 (6), pp. 1958 - 1967 (2019) Guberman, M.; Seeberger, P. H.: Automated Glycan Assembly: A Perspective. Journal of the American Chemical Society 141 (14), pp. 5581 - 5592 (2019) Jaenisch, T.; Heiss, K.; Fischer, N.; Geiger, C.; Bischoff, F. R.; Moldenhauer, G.; Rychlewski, L.; Sié, A.; Coulibaly, B.; Seeberger, P. H. et al.: High-density peptide arrays help to identify linear immunogenic B cell epitopes in individuals naturally exposed to malaria infection. Molecular and Cellular Proteomics 18 (4), pp. 642 - 656 (2019) Yu, Y.; Gim, S.; Kim, D.; Arnon, Z. A.; Gazit, E.; Seeberger, P. H.; Delbianco, M.: Oligosaccharides self-assemble and show intrinsic optical properties. Journal of the American Chemical Society 141 (12), pp. 4833 - 4838 (2019) Hu, J.; Wei, P.; Seeberger, P. H.; Yin, J.: Mannose-functionalized Nanoscaffolds for Targeted Delivery in Biomedical Applications. Chemistry – An Asian Journal 13 (22), pp. 3448 - 3459 (2018) Mucha, E.; Marianski, M.; Xu, F.-F.; Thomas, D. A.; Meijer, G.; von Helden, G.; Seeberger, P. H.; Pagel, K.: Unravelling the structure of glycosyl cations via cold-ion infrared spectroscopy. Nature Communications 9, 4174 (2018) Riggs, D. L.; Hofmann, J.; Hahm, H. S.; Seeberger, P. H.; Pagel, K.; Julian, R. R.: Glycan Isomer Identification Using Ultraviolet Photodissociation Initiated Radical Chemistry. Analytical Chemistry 90 (19), pp. 11581 - 11588 (2018) Pardo-Vargas, A.; Delbianco, M.; Seeberger, P. H.: Automated glycan assembly as an enabling technology. Current Opinion in Chemical Biology 46, pp. 48 - 55 (2018) Chatterjee, S.; Moon, S.; Hentschel, F.; Gilmore, K.; Seeberger, P. H.: An Empirical Understanding of the Glycosylation Reaction. Journal of the American Chemical Society 140 (38), pp. 11942 - 11953 (2018) Pieber, B.; Shalom, M.; Antonietti, M.; Seeberger, P. H.; Gilmore, K.: Continuous Heterogeneous Photocatalysis in Serial Micro-Batch Reactors. Angewandte Chemie International Edition 130 (31), pp. 10127 - 10131 (2018) Mucha, E.; Lettow, M.; Marianski, M.; Thomas, D. A.; Struwe, W. B.; Harvey, D. J.; Meijer, G.; Seeberger, P. H.; von Helden, G.; Pagel, K.: Fucose Migration in Intact Protonated Glycan Ions: A Universal Phenomenon in Mass Spectrometry. Angewandte Chemie International Edition 57 (25), pp. 7440 - 7443 (2018) Bröcker, F.; Götze, S.; Hudon, J.; Rathwell, D. C. K.; Pereira, C. L.; Stallforth, P.; Chakkumkal, A.; Seeberger, P. H.: Synthesis, Liposomal Formulation, and Immunological Evaluation of a Minimalistic Carbohydrate-α-GalCer Vaccine Candidate. Journal of Medicinal Chemistry 61 (11), pp. 4918 - 4927 (2018) Ota, F.; Hirayama, T.; Kizuka, Y.; Yamaguchi, Y.; Fujinawa, R.; Nagata, M.; Ismanto, H. S.; Lepenies, B.; Aretz, J.; Rademacher, C. et al.: High affinity sugar ligands of C-type lectin receptor langerin. Biochimica et Biophysica Acta (BBA) - General Subjects 1862 (7), pp. 1592 - 1601 (2018) Giglio, V.; Varela-Aramburu, S.; Travaglini, L.; Fiorini, F.; Seeberger, P. H.; Maggini, L.; Cola, L. D.: Reshaping Silica Particles: Mesoporous Nanodiscs for Bimodal Delivery and Improved Cellular Uptake. Chemical Engineering Journal 340, pp. 148 - 154 (2018) Triemer, S.; Gilmore, K.; Vu, G. T.; Seeberger, P. H.; Seidel-Morgenstern, A.: Literally green chemical synthesis of artemisinin from plant extracts. Angewandte Chemie International Edition 57 (19), pp. 5525 - 5528 (2018)