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个人简介

教育情况 2011/04-2011/08美国加州大学圣塔-芭芭拉化学与生物化学系,访问学者,合作导师:R. Daniel Little 2001/10-2003/04以色列Ben-Gurion大学化学系,博士后,合作导师:James Y. Becker 1998/09-2001/07中国科学院化学研究所,博士研究生,导师:黄志镗院士 1995/09-1998/07华中师范大学有机合成研究所,硕士研究生,导师:刘钊杰教授 1988/09-1991/06江西吉安师范专科学校化学系,学生 工作经历 2012/01-现在北京工业大学生命学院,教授,博士生导师 2011/04-2011/08美国加州大学圣塔-芭芭拉化学与生物化学系,访问学者 2011/01-现在北京工业大学生命学院,教授 2004/01-2010/12北京工业大学生命学院,副研究员,硕士生导师 2003/08-2003/12北京工业大学生命学院,教师

研究领域

1.有机电化学合成基础与工业电化学 2.HIV-1整合酶抑制剂的设计与合成。

近期论文

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Jie Chen, Wei-Qing Yan, Chiu Marco Lam, Cheng-Chu Zeng,* Li-Ming Hu, and R. Daniel Little*, Electrocatalytic aziridination of alkenes mediated by n-Bu4NI: a radical pathway Org. Lett. 2015, 17, 986-989. Sen Liang, Cheng-Chu Zeng,* Xu-Gang Luo, Fa-zheng Ren, Hong-Yu Tian, Bao-Guo Sun* and R. Daniel Little Electrochemically catalyzed amino-oxygenation of styrenes: a n-Bu4NI induced C-N followed by C-O bond formation cascade for the synthesis of indolines Green Chemistry, 2015, DOI: 10.1039/C5GC02626A Long-Ji Li, Yang-Ye Jiang, Chiu Marco Lam, Cheng-Chu Zeng, * Li-Ming Hu and R. Daniel Little, * Aromatic C-H bond functionalization induced by electrochemically in situ generated tris(p-bromophenyl)aminium (TBPA) radical cation: cationic chain reactions of electron-rich aromatics with enamides J. Org. Chem., 2015, 80, 11021-11030. Jie Chen, Cheng-Fu Liu, Cheng-Wen Yang, Cheng-Chu Zeng*, Wei Liu, Li-Ming Hu, Design and synthesis of 5-chloro-2-hydroxy-3-triazolylbenzoic acids as HIV integrase inhibitors Med. Chem. Res. 2015, 24, 2950-2959. Seung Joon Yoo, Long-Ji Li, Cheng-Chu Zeng, R. Daniel Little* Polymeric Ionic Liquid and Carbon Black Composite as a Reusable Supporting Electrolyte: Modification of the Electrode Surface Angew. Chem. Int. Ed. 2015, 54, 3744-3747. Nan-ning Lu, Ni-tao Zhang, Cheng-Chu Zeng,* Li-Ming Hu, Seung Joon Yoo, R. Daniel Little* Electrochemically induced ring-opening/Friedel-Crafts arylation of chalcone epoxides catalyzed by a triarylimidazole redox mediator J. Org. Chem., 2015, 80, 781-789. Yue-Xia Bai, Long ji Li, Xiao-Li Wang, Cheng-Chu Zeng*, Li-Ming Hu, Design and synthesis of N-hydroxy-triazole-4-carboxamides as HIV integrase inhibitors Med. Chem. Res. 2015, 24, 423-429. Nan-ning Lu, Seung Joon Yoo, Long-Jie Li, Cheng-Chu Zeng, * R. Daniel Little * A comparative study of organic electron transfer redox mediators: electron transfer kinetics for triarylimidazole and triarylamine mediators in the oxidation of 4-methoxybenzyl alcohol Electrochim. Acta, 2014. 142, 254-260. Wei-Jing Gao, Wei-Cui Li, Cheng-Chu Zeng,* Hong-Yu Tian, Li-Ming Hu, R. Daniel Little* Electrochemically initiated oxidative amination of benzoxazoles using tetraalkylammonium halides as redox catalysts J. Org. Chem. 2014, 79,9613-9618. Huan-Lan Xiao, Cheng-Chu Zeng,* Hong-Yu Tian, Li-Ming Hu, R. Daniel Little Electrochemical synthesis of 3,5-disubstituted isoxazoles J. Electroanal. Chem. 2014, 727, 120-124. Yong Dong Liu,* Meric Selbes, Chengchu Zeng, Rugang Zhong, Tanju Karanfil Formation Mechanism of NDMA from Ranitidine, Trimethylamine and Other Tertiary Amines during Chloramination: A Computational Study Environ. Sci. Technol. 2014, 48, 8653−8663. Wei-Cui Li, Zheng-Zheng Zhang, Cheng-Chu Zeng,* Li-Ming Hu, Hong-Yu Tian Electrogenerated Base Induced Dehydrodimerization and Dehydrotrimerization of Pyrazolones Curr. Org. Synth. 2014, 11, 454-460. Xiao-Guang Gao, Ni-Tao Zhang, Cheng-Chu Zeng *, Yong-Dong Liu, Li-Ming Hu, Hong-Yu Tian Electrochemical Synthesis of Polyfunctionalized Indoles in Aqueous Medium from Catechols and Ketene N,S-acetals Curr. Org. Synth. 2014, 11, 141-148. Wei-Cui Li, Cheng-Chu Zeng,* Li-Ming Hu, Hong-Yu Tian, R. Daniel Little Efficient indirect electrochemical synthesis of 2-substituted benzoxazoles using NaI as a mediator Adv. Synth. Cat. 2013, 355, 2884-2890. Chao Li, Cheng-Chu Zeng,* Li-Ming Hu, Feng-Lin Yang, Seung Joon Yoo, R. Daniel Little Electrochemically induced C-H functionalization using bromide ion/TEMPO dual redox catalysts in a two-phase electrolytic system Electrochimica Acta 2013, 114,560-566. Huan-Lan Xiao, Cheng-Wen Yang, Ni-Tao Zhang, Cheng-Chu Zeng*, Li-Ming Hu, Hong-Yu Tian, R. Daniel Little Electrochemical oxidation of aminophenols in the presence of benzenesulfinate Tetrahedron, 2013, 69, 658-663. Ni-tao Zhang, Cheng-chu Zeng,* Chiu Marco Lam, Randi K. Gbur, R. Daniel Little* Triarylimidazole Redox Catalysts: Electrochemical Analysis and Empirical Correlations J. Org. Chem. 2013, 78, 2104-2110. Efrat Korin, Beny Cohen, * Yong-Dong Liu, Cheng-Chu Zeng, * Alexander I. Shames, James Y. Becker* Examining the binding mechanism of 3,4-dihydro-3-(2-oxo-2-phenylethylidene)-quinoxalin-2(1H)-one and its fragments to Cu2+ J. Coord. Chem. 2013, 66, 2351-2366. Zeng, Cheng-Chu*; Zhang Ni-tao; Lam, C. M.; Little, R. D.* Novel triarylimidazole redox catalysts: synthesis, electrochemical properties and applicability to electrooxidative C-H activation Org. Lett. 2012, 14, 1314-1317. Cheng-Wen Yang, Yue-Xia Bai, Ni-Tao Zhang, Cheng-Chu Zeng*, Li-Ming Hu, Hong-Yu Tian One-pot sequential combination of multi-component and multi-catalyst: synthesis of 5-aminobenzofurans from aminophenol and ketene acetals Tetrahedron 2012, 68, 10201-10208.

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